Results 41 to 50 of about 13,836,709 (221)

Identification of risk factors associated with oral 5-aminolevulinic acid induced adverse events in photodynamic diagnosis−transurethral resection of bladder tumor

Photodiagnosis and Photodynamic Therapy
Background: Oral 5-aminolevulinic acid for transurethral resection of bladder tumor reduces bladder cancer recurrence compared with standard white-light transurethral resection of bladder tumor.
Yu Okabe, Yuichiro Fukuhara, Wataru Matsuoka, Nobuyuki Nakamura, Hiroshi Matsuzaki, Takeshi Miyazaki, Naotaka Gunge, Kosuke Tominaga, Kazuna Tsubouchi, Masahiro Tachibana, Chizuru Nakagawa, Fumihiro Yamazaki, Nobuhiro Haga   +12 more
doaj   +1 more source

Glioblastoma‐derived extracellular vesicle subpopulations following 5‐aminolevulinic acid treatment bear diagnostic implications

Journal of Extracellular Vesicles, 2022
Liquid biopsy is a minimally invasive alternative to surgical biopsy, encompassing different analytes including extracellular vesicles (EVs), circulating tumour cells (CTCs), circulating tumour DNA (ctDNA), proteins, and metabolites.
Tiffaney Hsia, Anudeep Yekula, S. Maheen Batool, Yulia B. Rosenfeld, Dong Gil You, Ralph Weissleder, Hakho Lee, Bob S. Carter, Leonora Balaj   +8 more
doaj   +1 more source

Detection of Canine Urothelial Carcinoma Cells in Urine Using 5-Aminolevulinic Acid

Animals, 2022
This study aimed to establish a method to detect canine urothelial carcinoma cells in urine using 5-aminolevulinic acid (5-ALA) and to evaluate its diagnostic accuracy.
Kenjiro Kaji, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda   +3 more
doaj   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

A case in which bladder cancer invaded the ureteral orifice and was resected via photodynamic diagnosis‐assisted transurethral resection involving orally administered 5‐aminolevulinic acid

IJU Case Reports, 2019
Introduction Transurethral resection of bladder tumor is widely used in combination with photodynamic diagnosis to treat non‐muscle invasive bladder cancer.
Keitaro Watanabe, Suguru Shirotake, Yuta Umezawa, Takayuki Takahashi, Takeshi Yamanaka, Noriaki LSanto, Takashi Okabe, Gou Kaneko, Katsuhiro Sano, Masanori Yasuda, Kent Kanao, Masafumi Oyama, Koshiro Nishimoto   +12 more
doaj   +1 more source

Comparative experimental study of 5-ALA and 5-ALA hexyl ester specific activity

Biomedical Photonics, 2018
A comparative experimental study of the specific activity of drugs based on 5-aminolevulinic acid (5-ALA) and its hexyl ester (5-ALA HE) was carried out. Their ability to induce the synthesis of photoactive protoporphyrin IX in the healthy tissues of the
R. I. Yakubovskaya, A. A. Pankratov, E. V. Filonenko, E. A. Lukyanets, V. I. Ivanova-Radkevich, A. A. Trushin, A. D. Kaprin   +6 more
doaj   +1 more source

Biopolymer‐Based Polyelectrolyte Nanoplatforms for Targeted Photodynamic Therapy of Breast Cancer

VIEW, EarlyView.
Illustration of the synthesis of 5‐aminolevulinic acid loaded chitosan‐sericin polyelectrolyte nanoparticles (CSSN/ALA NPs) using the Flash nanocomplexation (FNC) technique and their potential in photodynamic therapy (PDT) against breast cancer (BC). Abstract Nanomedicine has reshaped healthcare, especially in targeted drug delivery systems (DDSs) and ...
Athira Narayanan, Benedetta di Chiara Stanca, Daniela Pinheiro, Laura Giannotti, Fabrizio Damiano, André Ferreira Moreira, Sónia Miguel, Leonardo Lamanna, Eleonora Stanca, Maria Grazia Raucci, Gianpiero Colangelo, Luisa Siculella, Alessandro Sannino, Paula Coutinho, Christian Demitri   +14 more
wiley   +1 more source

Pretreatment with 5-aminolevulinic acid mitigates heat stress of cucumber leaves

, 2012
Cucumber seedlings were pretreated with 3 μM 5-aminolevulinic acid (ALA) followed by cultivation at normal (25/18 °C) or high (42/38 °C) day/night temperature to investigate the protective effects of ALA on heat stress in plants.
D. -M. Li, J. Zhang, J. -G. Bai, B. Yu, C. -X. Xia, Y. Gao   +5 more
core   +1 more source

Active and Higher Intracellular Uptake of 5-Aminolevulinic Acid in Tumors may be Inhibited by Glycine [PDF]

, 1999
Topical 5-aminolevulinic acid is used for the fluorescence-based diagnosis and photodynamic treatment of superficial precancerous and cancerous lesions of the skin.
Abels, Christoph, Rick, Kai, Langer, Stefan, Goetz, Alwin E., Botzlar, Andreas, Szeimies, Rolf-Markus, Pahernik, Sascha   +6 more
core   +1 more source

Photodynamic therapy of Bowen’s disease

Biomedical Photonics
Bowen’s disease is a form of non-invasive (in situ) squamous cell skin cancer localized in the non-genital area. Russian and European clinical guidelines include photodynamic therapy (PDT) in the standard of care for patients with Bowen’s disease. In the
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj   +1 more source