Results 51 to 60 of about 15,420 (189)

Photodynamic therapy in the treatment of patients with mycosis fungoides

Biomedical Photonics, 2022
The review highlights the current understanding of the epidemiology, etiology, pathogenesis, existing classifications of mycosis fungoides. Methods for diagnosis and treatment of the pathology are described, among which photodynamic therapy (PDT) plays ...
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

The FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb, Dominik Hörtnagel, Chris Oostenbrink, Paul G. Furtmüller, Stefan Hofbauer   +4 more
wiley   +1 more source

Simulated daylight versus conventional PDT for mild to moderate actinic keratoses: A randomized controlled trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This single‐centre, randomized controlled trial showed that simulated daylight photodynamic therapy (SDL‐PDT, n = 785 lesions) was less effective than conventional photodynamic therapy (C‐PDT, n = 673 lesions) in treating mild to moderate actinic keratoses with 1‐year clearance rates of 71.0% for SDL‐PDT versus 85.3% for C‐PDT (p < 0.001). However, SDL‐
Alexandra Sjöholm, Eva Backman, Maja Modin, Julia Fougelberg, Magdalena Claeson, John Paoli   +5 more
wiley   +1 more source

Characteristics of Fluorescent Intraoperative Dyes Helpful in Gross Total Resection of High-Grade Gliomas—A Systematic Review

Diagnostics, 2020
Background: A very important aspect in the treatment of high-grade glioma is gross total resection to reduce the risk of tumor recurrence. One of the methods to facilitate this task is intraoperative fluorescence navigation.
Marek Mazurek, Bartłomiej Kulesza, Filip Stoma, Jacek Osuchowski, Sławomir Mańdziuk, Radosław Rola   +5 more
doaj   +1 more source

Beef‐Liver 5‐Aminolevulinic Acid Dehydratase [PDF]

European Journal of Biochemistry, 1972
Beef liver 5‐aminolevulinate dehydratase was purified 700‐fold by salt fractionation, heat treatment, gel filtration and ion‐exchange chromatography. The final product was homogeneous by electrophoretic, ultracentrifugal and immunological criteria and had a molecular weight, by the low‐speed equilibrium method, of 260000.
E L, Wilson, P E, Burger, E B, Dowdle
openaire   +2 more sources

Divergent roles of ent‐kaurene oxidase paralogs in rice momilactone biosynthesis

Journal of Integrative Plant Biology, EarlyView.
Rice contains a five‐gene tandem array of genes encoding members of the ent‐kaurene oxidase (KO) family, with OsKOL4 and OsKOL5 playing divergent roles in momilactone metabolism, but both acting in the production of antifungal and antibacterial phytoalexins, which are important for disease resistance.
Zhibiao Wang, Yiling Feng, Leiming You, Meimei Xu, Kristin Helwig, Riqing Li, Si Nian Char, Bing Yang, Reuben J. Peters   +8 more
wiley   +1 more source

Genetic factors affecting intraoperative 5-aminolevulinic acid-induced fluorescence of diffuse gliomas

Radiology and Oncology, 2017
In patients operated for malignant glioma, 5-aminolevulinic acid (5-ALA)-induced fluorescence guidance is useful. However, we occasionally experience instances of non-visible fluorescence despite a histopathological diagnosis of high-grade glioma.
Saito Kiyotaka, Hirai Toshinori, Takeshima Hideo, Kadota Yoshihito, Yamashita Shinji, Ivanova Asya, Yokogami Kiyotaka   +6 more
doaj   +1 more source

5-Aminolevulinic acid-induced severe hypotension during transurethral resection of a bladder tumor: a case report

JA Clinical Reports, 2019
Background Although 5-aminolevulinic acid (5-ALA) is used for the photodynamic diagnosis of bladder tumors, hypotension is the most commonly observed adverse effect.
Tomoaki Yatabe, Shigematsu-Locatelli Marie, Hideo Fukuhara, Takeshi Karashima, Keiji Inoue, Masataka Yokoyama   +5 more
doaj   +1 more source

Mechanisms of 5‐Aminolevulinic Acid Uptake at the Choroid Plexus [PDF]

Journal of Neurochemistry, 2000
Abstract : 5‐Aminolevulinic acid (5‐ALA) is a precursor of porphyrins and heme that has been implicated in the neuropsychiatric symptoms associated with porphyrias. It is also being used clinically to delineate malignant gliomas. The blood‐CSF barrier may be an important interface for 5‐ALA transport between blood and brain as in vivo studies ...
A, Novotny, J, Xiang, W, Stummer, N S, Teuscher, D E, Smith, R F, Keep   +5 more
openaire   +2 more sources

MdPHYB2‐MdPIF1 Module Regulates Transcription Factors to Mediate Light‐Dependent ALA‐Induced Apple Anthocyanin Biosynthesis

Plant, Cell &Environment, EarlyView.
ABSTRACT Light is a primary environmental signal that induces plant anthocyanin accumulation. The plant growth regulator 5‐aminolevulinic acid (ALA) has also been proven to effectively promote anthocyanin accumulation in apple. However, the underlying regulatory mechanisms remain unknown.
Liuzi Zhang, Yuyan An, Jianting Zhang, Liangju Wang   +3 more
wiley   +1 more source