Results 51 to 60 of about 34,838 (281)

White-light toxicity, resulting from systemically administered 5-aminolevulinic acid, under normal operating conditions [PDF]

, 1999
This study has investigated damage to the intraperitoneal organs of the rat after systemic (intraperitoneal and intravenous) administration of low doses of 5-aminolevulinic acid (ALA) and illumination with a standard white-light operating-room (o.r ...
Aalders, M.J.A.M., Klein, M.G. (Marloes), Sterenborg, H.J.C.M. (Dick), Stewart, F.A., Vange, N.V.D. (Nine), Vijver, M.J.V.D. (Mark)   +5 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Severe hypotension and postoperative cardiac arrest caused by 5-aminolevulinic acid: a case report

Journal of Medical Case Reports
Background Although 5-aminolevulinic acid is useful for the photodynamic diagnosis of bladder tumors, it often causes severe intraoperative hypotension.
Taishi Miyazaki, Shinya Taguchi, Norihiko Obata, Satoshi Mizobuchi   +3 more
doaj   +1 more source

5-Aminolevulinic acid fermentation using engineered Saccharomyces cerevisiae

Microbial Cell Factories, 2019
Background 5′-Aminolevulinic acid (ALA) is widely used in the pharmaceutical industry, healthcare, and food production, and is a substrate for the biosynthesis of heme, which is required for respiration and photosynthesis. Enhancement of ALA biosynthesis
Kiyotaka Y. Hara, Masaru Saito, Hiroko Kato, Kana Morikawa, Hiroshi Kikukawa, Hironari Nomura, Takanori Fujimoto, Yoko Hirono-Hara, Shigeyuki Watanabe, Kengo Kanamaru, Akihiko Kondo   +10 more
doaj   +1 more source

Long-term effects of red- and blue-light emitting diodes on leaf anatomy and photosynthetic efficiency of three ornamental pot plants [PDF]

, 2017
Light quality critically affects plant development and growth. Development of light-emitting diodes (LEDs) enables the use of narrow band red and/or blue wavelengths as supplementary lighting in ornamental production.
Van Labeke, Marie-Christine, Zheng, Liang   +1 more
core   +3 more sources

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Identification of risk factors associated with oral 5-aminolevulinic acid induced adverse events in photodynamic diagnosis−transurethral resection of bladder tumor

Photodiagnosis and Photodynamic Therapy
Background: Oral 5-aminolevulinic acid for transurethral resection of bladder tumor reduces bladder cancer recurrence compared with standard white-light transurethral resection of bladder tumor.
Yu Okabe, Yuichiro Fukuhara, Wataru Matsuoka, Nobuyuki Nakamura, Hiroshi Matsuzaki, Takeshi Miyazaki, Naotaka Gunge, Kosuke Tominaga, Kazuna Tsubouchi, Masahiro Tachibana, Chizuru Nakagawa, Fumihiro Yamazaki, Nobuhiro Haga   +12 more
doaj   +1 more source

Glioblastoma‐derived extracellular vesicle subpopulations following 5‐aminolevulinic acid treatment bear diagnostic implications

Journal of Extracellular Vesicles, 2022
Liquid biopsy is a minimally invasive alternative to surgical biopsy, encompassing different analytes including extracellular vesicles (EVs), circulating tumour cells (CTCs), circulating tumour DNA (ctDNA), proteins, and metabolites.
Tiffaney Hsia, Anudeep Yekula, S. Maheen Batool, Yulia B. Rosenfeld, Dong Gil You, Ralph Weissleder, Hakho Lee, Bob S. Carter, Leonora Balaj   +8 more
doaj   +1 more source

Detection of Canine Urothelial Carcinoma Cells in Urine Using 5-Aminolevulinic Acid

Animals, 2022
This study aimed to establish a method to detect canine urothelial carcinoma cells in urine using 5-aminolevulinic acid (5-ALA) and to evaluate its diagnostic accuracy.
Kenjiro Kaji, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda   +3 more
doaj   +1 more source

5-Aminolevulinic Acid Fluorescence in Detection of Peritoneal Metastases [PDF]

Asian Pacific Journal of Cancer Prevention, 2016
The value of 5-aminolevulinic acid (ALA) in fluorescence detection of peritoneal metastases and the underlying mechanisms were evaluated in patients with peritoneal surface malignancies.Oral 5-ALA was administered at a concentration of 20 mg ⁄kg body weight with 50 ml of water 2 hours prior to surgery (n=115).
Yutaka Yonemura, Emel Canbay, Haruaki Ishibashi, Eisei Nishino, Yoshio Endo, Shouzou Sako, Shun-ichiro Ogura   +6 more
openaire   +2 more sources