Results 71 to 80 of about 34,838 (281)
Cell membrane‐coated nanoparticles for dermatological diseases
Skin disorders are challenging to treat due to complex barrier functions and limited conventional therapies. Biomimetic cell membrane‐coated nanoparticles (CM‐NPs) offer a superior nanomedicine approach by evading immune detection and enabling precise targeting.
Shuaijun Zou, Baojie Zhang, Yuanjie Zhu
wiley +1 more source
Photodynamic therapy in the treatment of onychomycosis – a review
Toenail onychomycosis is a common infection, affecting up to 14% of the population. Moreover, poor penetration of topical drugs into the nail bed leads to frequent recurrences of the disease. The cure rate of toenail onychomycosis is estimated at 63–76%.
Katarzyna Kalinowska +1 more
doaj +1 more source
Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics. [PDF]
The vitamin B12 family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria ...
Haft, David R +6 more
core +1 more source
The Adverse Effects of Topical Photodynamic Therapy:a consensus review and approach to management [PDF]
Background: Topical photodynamic therapy (PDT) is widely used to treat superficial nonmelanoma skin cancer and dysplasia, and is generally well tolerated.
Babilas P +17 more
core +2 more sources
Beef‐Liver 5‐Aminolevulinic Acid Dehydratase [PDF]
Beef liver 5‐aminolevulinate dehydratase was purified 700‐fold by salt fractionation, heat treatment, gel filtration and ion‐exchange chromatography. The final product was homogeneous by electrophoretic, ultracentrifugal and immunological criteria and had a molecular weight, by the low‐speed equilibrium method, of 260000.
E L, Wilson, P E, Burger, E B, Dowdle
openaire +2 more sources
ABSTRACT Background There is compelling evidence that treating high‐grade squamous intraepithelial lesions (HSIL), the anal squamous cell cancer (ASCC) precursor, reduces the risk of developing ASCC. Using high‐resolution anoscopy (HRA), surgical excision, ablative and topical therapies are widely used to treat HSIL.
Matthew Joseph Marino +5 more
wiley +1 more source
Background Although 5-aminolevulinic acid (5-ALA) is used for the photodynamic diagnosis of bladder tumors, hypotension is the most commonly observed adverse effect.
Tomoaki Yatabe +5 more
doaj +1 more source
Background: A very important aspect in the treatment of high-grade glioma is gross total resection to reduce the risk of tumor recurrence. One of the methods to facilitate this task is intraoperative fluorescence navigation.
Marek Mazurek +5 more
doaj +1 more source
Heme biosynthesis and its regulation: towards understanding and improvement of heme biosynthesis in filamentous fungi [PDF]
Heme biosynthesis in fungal host strains has acquired considerable interest in relation to the production of secreted heme-containing peroxidases.
Weert, S. de +6 more
core +2 more sources
Mechanisms of 5‐Aminolevulinic Acid Uptake at the Choroid Plexus [PDF]
Abstract : 5‐Aminolevulinic acid (5‐ALA) is a precursor of porphyrins and heme that has been implicated in the neuropsychiatric symptoms associated with porphyrias. It is also being used clinically to delineate malignant gliomas. The blood‐CSF barrier may be an important interface for 5‐ALA transport between blood and brain as in vivo studies ...
A, Novotny +5 more
openaire +2 more sources

