Results 71 to 80 of about 34,838 (281)

Cell membrane‐coated nanoparticles for dermatological diseases

open access: yesVIEW, EarlyView.
Skin disorders are challenging to treat due to complex barrier functions and limited conventional therapies. Biomimetic cell membrane‐coated nanoparticles (CM‐NPs) offer a superior nanomedicine approach by evading immune detection and enabling precise targeting.
Shuaijun Zou, Baojie Zhang, Yuanjie Zhu
wiley   +1 more source

Photodynamic therapy in the treatment of onychomycosis – a review

open access: yesPrzegląd Dermatologiczny, 2017
Toenail onychomycosis is a common infection, affecting up to 14% of the population. Moreover, poor penetration of topical drugs into the nail bed leads to frequent recurrences of the disease. The cure rate of toenail onychomycosis is estimated at 63–76%.
Katarzyna Kalinowska   +1 more
doaj   +1 more source

Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics. [PDF]

open access: yes, 2019
The vitamin B12 family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria ...
Haft, David R   +6 more
core   +1 more source

The Adverse Effects of Topical Photodynamic Therapy:a consensus review and approach to management [PDF]

open access: yes, 2019
Background: Topical photodynamic therapy (PDT) is widely used to treat superficial nonmelanoma skin cancer and dysplasia, and is generally well tolerated.
Babilas P   +17 more
core   +2 more sources

Beef‐Liver 5‐Aminolevulinic Acid Dehydratase [PDF]

open access: yesEuropean Journal of Biochemistry, 1972
Beef liver 5‐aminolevulinate dehydratase was purified 700‐fold by salt fractionation, heat treatment, gel filtration and ion‐exchange chromatography. The final product was homogeneous by electrophoretic, ultracentrifugal and immunological criteria and had a molecular weight, by the low‐speed equilibrium method, of 260000.
E L, Wilson, P E, Burger, E B, Dowdle
openaire   +2 more sources

Efficacy and Safety of Anal High‐Grade Squamous Intraepithelial Lesion Treatment Modalities: A Systematic Review

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background There is compelling evidence that treating high‐grade squamous intraepithelial lesions (HSIL), the anal squamous cell cancer (ASCC) precursor, reduces the risk of developing ASCC. Using high‐resolution anoscopy (HRA), surgical excision, ablative and topical therapies are widely used to treat HSIL.
Matthew Joseph Marino   +5 more
wiley   +1 more source

5-Aminolevulinic acid-induced severe hypotension during transurethral resection of a bladder tumor: a case report

open access: yesJA Clinical Reports, 2019
Background Although 5-aminolevulinic acid (5-ALA) is used for the photodynamic diagnosis of bladder tumors, hypotension is the most commonly observed adverse effect.
Tomoaki Yatabe   +5 more
doaj   +1 more source

Characteristics of Fluorescent Intraoperative Dyes Helpful in Gross Total Resection of High-Grade Gliomas—A Systematic Review

open access: yesDiagnostics, 2020
Background: A very important aspect in the treatment of high-grade glioma is gross total resection to reduce the risk of tumor recurrence. One of the methods to facilitate this task is intraoperative fluorescence navigation.
Marek Mazurek   +5 more
doaj   +1 more source

Heme biosynthesis and its regulation: towards understanding and improvement of heme biosynthesis in filamentous fungi [PDF]

open access: yes, 1982
Heme biosynthesis in fungal host strains has acquired considerable interest in relation to the production of secreted heme-containing peroxidases.
Weert, S. de   +6 more
core   +2 more sources

Mechanisms of 5‐Aminolevulinic Acid Uptake at the Choroid Plexus [PDF]

open access: yesJournal of Neurochemistry, 2000
Abstract : 5‐Aminolevulinic acid (5‐ALA) is a precursor of porphyrins and heme that has been implicated in the neuropsychiatric symptoms associated with porphyrias. It is also being used clinically to delineate malignant gliomas. The blood‐CSF barrier may be an important interface for 5‐ALA transport between blood and brain as in vivo studies ...
A, Novotny   +5 more
openaire   +2 more sources

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