Results 11 to 20 of about 15,420 (189)

The use of 5-aminolevulinic acid and its derivatives in photodynamic therapy and diagnosis [PDF]

Biuletyn Wojskowej Akademii Technicznej, 2018
5-aminolevulinic acid (5-ALA) is used as a drug in the photodynamic therapy (PDT) and photodynamic diagnosis (PDD) of cancer. Combined with irradiation at the appropriate wavelength, it is used as a photosensitizer precursor to identify/kill tumour cells.
Anna Romiszewska, Aneta Bombalska
doaj   +1 more source

5‐Aminolevulinic Acid Dehydratase [PDF]

European Journal of Biochemistry, 1981
The thiophilic reagent 5,5′‐dithiobis(2‐nitrobenzoic acid) (Nbs2) reacts with four sulphydryl groups in native 5‐aminolevulinic acid dehydratase from bovine liver (groups I, II, III and IV). All four of these groups exhibit various degrees of half‐site reactivity.
J S, Seehra, M G, Gore, A G, Chaudhry, P M, Jordan   +3 more
openaire   +2 more sources

5-Aminolevulinic Acid and Red Led in Endodontics: A Narrative Review and Case Report

Gels, 2022
The present study aims to discuss the main factors involving the use of 5-aminolevulinic acid together with red LED light and its application in endodontic treatment through a narrative review and a case report. Persistence of microorganisms remaining on
Simonetta D’Ercole, Teocrito Carlesi, Tatiane Cristina Dotta, Tania Vanessa Pierfelice, Emira D’Amico, Domenico Tripodi, Giovanna Iezzi, Adriano Piattelli, Morena Petrini   +8 more
doaj   +1 more source

Photodynamic therapy in the treatment of extramammary paget’s disease

Biomedical Photonics, 2022
Extramammary Paget’s disease (EMPD) is a rare tumor that predominantly affects the skin containing apocrine glands. Due to insufficient data on the effectiveness of different methods, there is no single therapeutic approach to the treatment of patients ...
E. V. Filonenko, V. Ivanova-Radkevich
doaj   +1 more source

Effects on Gram-Negative and Gram-Positive Bacteria Mediated by 5-Aminolevulinic Acid and 5-Aminolevulinic Acid Derivatives [PDF]

Antimicrobial Agents and Chemotherapy, 2008
ABSTRACT Due mainly to the extensive use of antibiotics, the spread of multiresistant bacterial strains is one of the most worrying threats to public health. One strategy that can be used to overcome potential shortcomings might be the inactivation of these microorganisms by 5-aminolevulinic acid (5-ALA) or 5-ALA derivative ...
Fotinos, Nicolas, Convert, Maruska, Piffaretti, Jean-Claude, Gurny, Robert, Lange, Norbert   +4 more
openaire   +4 more sources

Identification of risk factors for post-induction hypotension in patients receiving 5-aminolevulinic acid: a single-center retrospective study

JA Clinical Reports, 2020
Background 5-Aminolevulinic acid (5-ALA) is useful as a photodynamic agent, but its use commonly leads to hypotension. Although avoiding a mean arterial pressure (MAP) < 60 mmHg is important, the incidence of MAP < 60 mmHg when using 5-ALA is unclear ...
Tomoaki Yatabe, Takashi Karashima, Motohiko Kume, Yu Kawanishi, Hideo Fukuhara, Tetsuya Ueba, Keiji Inoue, Yoshiyasu Okuhara, Masataka Yokoyama   +8 more
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A New Synthesis of 5-Aminolevulinic Acid.

Agricultural and Biological Chemistry, 1991
(1991). A New Synthesis of 5-Aminolevulinic Acid. Agricultural and Biological Chemistry: Vol. 55, No. 6, pp. 1687-1688.
KAWAKAMI, Hiroshi, EBATA, Takashi, MATSUSHITA, Hajime   +2 more
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5-Aminolevulinic acid synthesis in Escherichia coli [PDF]

Journal of Bacteriology, 1989
A hemA mutant of Escherichia coli containing a multicopy plasmid which complemented the mutation excreted 5-aminolevulinic acid (ALA) into the medium. [1-14C]glutamate was substantially incorporated into ALA by this strain, whereas [2-14C]glycine was not. Periodate degradation of labeled ALA showed that C-5 of ALA was derived from C-1 of glutamate. The
J M, Li, O, Brathwaite, S D, Cosloy, C S, Russell   +3 more
openaire   +2 more sources

Systems metabolic engineering of Escherichia coli for hyper-production of 5‑aminolevulinic acid

Biotechnology for Biofuels and Bioproducts, 2023
Background 5-Aminolevulinic acid (5-ALA) is a promising biostimulant, feed nutrient, and photodynamic drug with wide applications in modern agriculture and therapy.
Wei Pu, Jiuzhou Chen, Yingyu Zhou, Huamin Qiu, Tuo Shi, Wenjuan Zhou, Xuan Guo, Ningyun Cai, Zijian Tan, Jiao Liu, Jinhui Feng, Yu Wang, Ping Zheng, Jibin Sun   +13 more
doaj   +1 more source

Stability of 5-aminolevulinic acid in aqueous solution

European Journal of Pharmaceutical Sciences, 1999
The chemical stability of 5-aminolevulinic acid (ALA) was studied in aqueous solution as a function of concentration, pH, temperature and in the presence of ethylenediaminetetraacetic acid (EDTA). The degradation of ALA was followed by reversed-phase liquid chromatography using a pH where ALA is protonated (pKa1=3.90; pKa2=8.
B, Elfsson, I, Wallin, S, Eksborg, K, Rudaeus, A M, Ros, H, Ehrsson   +5 more
openaire   +2 more sources