Photodynamic therapy using systemic administration of 5-aminolevulinic acid and a 410-nm wavelength light-emitting diode for methicillin-resistant Staphylococcus aureus-infected ulcers in mice. [PDF]
PLoS ONE, 2014 Bacterial resistance to antibiotics has become a worldwide problem. One potential alternative for bacterial control is photodynamic therapy. 5-aminolevulinic acid is a natural precursor of the photosensitizer protoporphyrin IX. Relatively little is known
Kuniyuki Morimoto +6 more
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Photodynamic therapy of psoriasis
Biomedical Photonics, 2023 Photodynamic therapy (PDT) in the treatment of psoriasis remains the subject of much debate. There is no consensus in the scientific community about effective and safe PDT regimens for psoriasis.
E. V. Filonenko, V. Ivanova-Radkevich
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Synthetic biology-instructed transdermal microneedle patch for traceable photodynamic therapy
Nature Communications, 2022 5-Aminolevulinic acid-based photodynamic therapy heavily depends on the biological transformation efficiency of 5-aminolevulinic acid to protoporphyrin IX, while the lack of an effective delivery system and imaging navigation are major hurdles in ...
Gang He +7 more
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The use of 5-aminolevulinic acid and its derivatives in photodynamic therapy and diagnosis [PDF]
Biuletyn Wojskowej Akademii Technicznej, 2018 5-aminolevulinic acid (5-ALA) is used as a drug in the photodynamic therapy (PDT) and photodynamic diagnosis (PDD) of cancer. Combined with irradiation at the appropriate wavelength, it is used as a photosensitizer precursor to identify/kill tumour cells.
Anna Romiszewska, Aneta Bombalska
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5‐Aminolevulinic Acid Dehydratase [PDF]
European Journal of Biochemistry, 1981 The thiophilic reagent 5,5′‐dithiobis(2‐nitrobenzoic acid) (Nbs2) reacts with four sulphydryl groups in native 5‐aminolevulinic acid dehydratase from bovine liver (groups I, II, III and IV). All four of these groups exhibit various degrees of half‐site reactivity.
J S, Seehra +3 more
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5-Aminolevulinic Acid and Red Led in Endodontics: A Narrative Review and Case Report
Gels, 2022 The present study aims to discuss the main factors involving the use of 5-aminolevulinic acid together with red LED light and its application in endodontic treatment through a narrative review and a case report. Persistence of microorganisms remaining on
Simonetta D’Ercole +8 more
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Photodynamic therapy in the treatment of extramammary paget’s disease
Biomedical Photonics, 2022 Extramammary Paget’s disease (EMPD) is a rare tumor that predominantly affects the skin containing apocrine glands. Due to insufficient data on the effectiveness of different methods, there is no single therapeutic approach to the treatment of patients ...
E. V. Filonenko, V. Ivanova-Radkevich
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Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy [PDF]
, 1999 Purpose: We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence.
Baumgartner, Reinhold +6 more
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Electronic and optical properties of 5-AVA-functionalized BN nanoclusters: A DFT study [PDF]
, 2016 We carried out detailed density functional theory (DFT) and time-dependent density functional theory (TD-DFT) calculations upon 5-aminolevulinic acid-functionalized B12N12 and B16N16 nanoclusters with the B3LYP, B3PW91, and PBE methods using the 6-311+G∗∗
Balakheyli, H. +4 more
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The current diagnosis of superficial bladder cancer must be reconsidered [PDF]
, 2002 The high recurrence and progression rates in superficial bladder cancer are partially related to the deficiencies of the standard conventional diagnostic modalities.
Hofstetter, Alfons, Zaak, Dirk
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