Results 21 to 30 of about 84,780,597 (237)

Anatomic study of verumontanum during endoscopic surgeries in patients with benign prostatic hyperplasia [PDF]

International Brazilian Journal of Urology, 2021
Introduction and objective: To evaluate changes in verumontanum anatomy in patients with benign prostatic hyperplasia (BPH) who used 5-alpha reductase inhibitors (5-ARIs) and to propose an anatomical classification of the verumontanum.
Henrique Barbosa de Menezes, Francisco José Barcellos Sampaio, José Anacleto Dutra de Resende Júnior, Rodrigo Ribeiro Vieiralves, Fernando Salles da Silva Filho, Edilaine Alves, Luciano Alves Favorito   +6 more
doaj   +1 more source

The Use of 5-Alpha Reductase Inhibitors to Manage Benign Prostatic Hyperplasia and the Risk of All-Cause Mortality [PDF]

Urology, 2018
Ralph I Horwitz, Lauren P Wallner, Stephen K Van Den Eeden   +2 more
exaly   +2 more sources

5-Alpha Reductase Inhibitors and the Risk of Prostate Cancer Mortality in Men Treated for Benign Prostatic Hyperplasia [PDF]

Mayo Clinic Proceedings, 2016
Ralph I Horwitz, Lauren P Wallner, Ralph B. D'Agostino Jr   +2 more
exaly   +2 more sources

Human prostatic steroid 5 alpha-reductase isoforms--a comparative study of selective inhibitors

, 1995
The present study describes the independent expression of the type 1 and 2 isoforms of human 5 alpha-reductase in the baculovirus-directed insect cell expression system and the selectivity of their inhibition.
Martin, P M, Guirou, Olivier, Tate, R, Raynaud, J P, Guirou, O, Iehlé, Catherine, Raynaud, Jean-Pierre, Tate, Rothwell, Iehlé, C, Délos, Sylvie, Délos, S, Martin, Pierre-Marie, Pierre-Marie Martin, Olivier Guirou, Jean-Pierre Raynaud, Catherine Iehlé, Rothwell Tate, Sylvie Délos   +17 more
core   +3 more sources

5 alpha-Reductase Inhibitors and Risk of Prostate Cancer Death

, 2020
Purpose: 5 alpha-Reductase inhibitors reduced the risk of prostate cancer in 25% in 2 randomized trials but increased the risk of Gleason 8-10 at biopsy. One explanation is that 5 alpha-reductase inhibitors induce morphological changes in prostate cancer
Robinson, David,, Stattin, Pär,, Garmo, Hans,, Miranda, Tiago Bonde,, Bonde Miranda, Tiago,   +4 more
core   +1 more source

Evaluation of Recent Trends in Treatment Patterns Among Men With Benign Prostatic Hyperplasia

American Journal of Men's Health, 2013
Although there is an abundance of evidence regarding clinical efficacy and safety of benign prostatic hyperplasia (BPH) treatment, real-world evidence is lacking for pharmacotherapy utilization and trends.
Eric J. Kruep PharmD, MS, Bridgett B. Goodwin PhD, Sham Chaudhari PharmD, MS   +2 more
doaj   +1 more source

Bothersome Hematospermia Following Stereotactic Body Radiation Therapy for Prostate Cancer

Frontiers in Oncology, 2021
BackgroundHematospermia following prostate radiation therapy is a benign and often self-limiting side effect. However, it may be bothersome to some men and their partners with a negative impact on sexual quality of life (QOL).
Sarthak Shah, Tamir Sholklapper, Michael Creswell, Abigail Pepin, Jonathan Cantalino, Ryan Andrew Hankins, Simeng Suy, Sean P. Collins   +7 more
doaj   +1 more source

5-alpha-reductase inhibitors for lower urinary tract symptoms secondary to benign prostatic obstruction

, 2020
This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effects of 5-alpha-reductase inhibitors (5ARIs) for treating lower urinary tract symptoms (LUTS) secondary to benign prostatic obstruction (BPO ...
Tacklind, James, García?Perdomo, Herney A, Lopez, Hugo E   +2 more
core   +1 more source

Structure based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1 [PDF]

, 2014
The treatment of Human African Trypanosomiasis remains a major unmet health need in sub-Saharan Africa. Approaches involving new molecular targets are important and pteridine reductase 1 (PTR1), an enzyme that reduces dihydrobiopterin in Trypanosoma spp.
Kirsten Stewart, Michael P. Barrett, Pui Ee Wong, William N. Hunter, Barrack, Keri L., Hunter, William N., Huggan, Judith, Colin L. Gibson, Judith K. Huggan, Barrett, Michael P., Federica Giordani, Suckling, Colin J., Colin J. Suckling, Khalaf, Abedawn I., Huggan, Judith K., Wong, Pui Ee, Khalaf, Abedawn I, Barrack, Keri L, Stewart, Kirsten, Keri L. Barrack, Suckling, Colin J, Hunter, Wililam N., Gibson, Colin L., Giordani, Federica, Gibson, Colin L, Abedawn I. Khalaf, Hunter, William N   +26 more
core   +1 more source

Effect of 5-alpha Reductase Inhibitor on Storage Symptoms in Patients with Benign Prostatic Hyperplasia [PDF]

International Neurourology Journal, 2011
Purpose Many patients with benign prostatic hyperplasia (BPH) have storage symptoms. The aim of this study was to evaluate the effects of treatment with a 5-alpha reductase inhibitor (5ARI) on storage symptoms in patients with BPH. Methods This study was
Kang Jun Cho, Se Hee Kang, Hyo Sin Kim, Jun Sung Koh, Joon Chul Kim   +4 more
doaj   +1 more source