Controlled release of dutasteride from biodegradable microspheres: in vitro and in vivo studies. [PDF]
PLoS ONE, 2014 The aim of the present work was to study the in vitro/in vivo characteristics of dutasteride loaded biodegradable microspheres designed for sustained release of dutasteride over four weeks.
Xiangyang Xie +6 more
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Antibody-Capped Mesoporous Nanoscopic Materials:Design of a Probe for the Selective Chromo-FluorogenicDetection of Finasteride [PDF]
, 2012 [EN] The synthesis of capped mesoporous silica nanoparticles (MSN) conjugated with an antibody (AB) as a gatekeeper has been carried out in order to obtain a delivery system able to release an entrapped cargo (dye) in the presence of a target molecule
Amoros del Toro, Pedro +7 more
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Effects of dutasteride and tamsulosin on penile morphology in a rodent model [PDF]
International Brazilian Journal of Urology, 2023 Purpose To evaluate the penile morphology after the isolated and combined administration of dutasteride and tamsulosin in a rodent model. Materials and Methods Forty male rats were assigned into the following groups: Control group (C, receiving ...
Marcello H. A. Da Silva +3 more
doaj +1 more source
A population-based study of the risk of osteoporosis and fracture with dutasteride and finasteride
BMC Musculoskeletal Disorders, 2018 Background Dutasteride is a potent inhibitor of 5-alpha reductase enzymes that reduces concentrations of dihydrotestosterone to a greater extent than finasteride. Whether this has adverse implications for bone health is unknown.
Tony Antoniou +8 more
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Patterns of finasteride and dutasteride use in the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial cohort: effects of socio-demographic factors and a black box warning [PDF]
Journal of Men's Health, 2022 Background: Five-alpha reductase inhibitors (5-ARIs), specifically finasteride and dutasteride, have been shown to significantly reduce prostate cancer incidence.
Jarrett A. Johnson +3 more
doaj +1 more source
Subcellular localization of the five members of the human steroid 5α-reductase family [PDF]
, 2017 In humans the steroid 5a-reductase (SRD5A) family comprises five integral membrane enzymes that carry out reduction of a double bond in lipidic substrates: D4-3-keto steroids, polyprenol and trans-enoyl CoA.
Asteriti, ITALIA ANNA +10 more
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PLoS ONE, 2019 Dutasteride, a dual inhibitor of both type I and II 5α-reductases, is used to treat male pattern hair loss (MPHL). However, patient response to dutasteride varies in each individual, the cause of which is yet to be identified.
Arang Rhie +10 more
doaj +1 more source
Cost effectiveness comparison of dutasteride and finasteride in patients with benign prostatic hyperplasia - the Markov model based on data from Montenegro [PDF]
Vojnosanitetski Pregled, 2016 Background/Aim. Benign prostatic hyperplasia (BPH) is one of the most common disease among males aging 50 years and more. The rise of the prevalence of BPH is related to aging, and since duration of life time period has the tendency of rising ...
Dabanović Vera +2 more
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The psychometric validation of a US English satisfaction measure for patients with benign prostatic hyperplasia and lower urinary tract symptoms [PDF]
, 2009 Background The purpose of the current study was to validate the US English Patient Perception of Study Medication (PPSM) questionnaire, which measures patient satisfaction with Benign Prostatic Hyperplasia (BPH) treatment and was administered to men with
Libby Black, Alyson Grove, Betsy Morrill
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Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iranian Journal of Allergy, Asthma and Immunology, 2022 Dutasteride was potentially proposed to control chronic pain by Toll-Like Receptor 4 (TLR4) inhibition through its effect on TLR4 expression, Myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa-light-chain-enhancer of activated B ...
Leila Taheran +7 more
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