Results 11 to 20 of about 4,735 (197)

Genetic variations associated with response to dutasteride in the treatment of male subjects with androgenetic alopecia.

open access: yesPLoS ONE, 2019
Dutasteride, a dual inhibitor of both type I and II 5α-reductases, is used to treat male pattern hair loss (MPHL). However, patient response to dutasteride varies in each individual, the cause of which is yet to be identified.
Arang Rhie   +10 more
doaj   +2 more sources

Effect of Dutasteride on the Risk of Prostate Cancer

open access: yesNew England Journal of Medicine, 2010
We conducted a study to determine whether dutasteride reduces the risk of incident prostate cancer, as detected on biopsy, among men who are at increased risk for the disease.In this 4-year, multicenter, randomized, double-blind, placebo-controlled, parallel-group study, we compared dutasteride, at a dose of 0.5 mg daily, with placebo.
Andriole, G.L.   +16 more
core   +11 more sources

Process Factors Affecting the Preparation and Characterization of Dutasteride Nanosuspension [PDF]

open access: yesIraqi Journal of Pharmaceutical Sciences
Dutasteride, a synthetic compound belonging to the 4-azasteroid class, functions as a selective and competitive inhibitor of both type 1 and type 2 5-alpha-reductase enzymes.
Shaimaa N. Abd-Alhammid   +1 more
doaj   +2 more sources

Effects of dutasteride and tamsulosin on penile morphology in a rodent model [PDF]

open access: yesInternational Brazilian Journal of Urology, 2023
Purpose To evaluate the penile morphology after the isolated and combined administration of dutasteride and tamsulosin in a rodent model. Materials and Methods Forty male rats were assigned into the following groups: Control group (C, receiving ...
Marcello H. A. Da Silva   +3 more
doaj   +2 more sources

The efficacy and safety of dutasteride compared with finasteride in treating men with androgenetic alopecia: a systematic review and meta-analysis

open access: yesClinical Interventions in Aging, 2019
Zhongbao Zhou,1,2,* Shiqiang Song,3,* Zhenli Gao,2 Jitao Wu,2 Jiajia Ma,2 Yuanshan Cui2 1School of clinical medicine, Binzhou Medical University, Yantai, Shandong, China; 2Department of Urology, The Affiliated Yantai Yuhuangding Hospital of Qingdao ...
Zhou Z, Song S, Gao Z, Wu J, Ma J, Cui Y
doaj   +1 more source

Integrated testing strategy for the study of the effects of the human pharmaceutical dutasteride on fish [PDF]

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In recent years, a growing number of human pharmaceuticals have been detected in the aquatic environment, generally at low concentrations (sub-ng/L to low ...
Margiotta-Casaluci, Luigi
core   +7 more sources

Combined therapy with dutasteride and tadalafil vs dutasteride or tadalafil monotherapy in benign prostatic hyperplasia: a randomised phase III trial. [PDF]

open access: yesBJU Int
OBJECTIVES: To evaluate the efficacy and safety of a fixed\u2010dose combination (FDC) of dutasteride and tadalafil vs monotherapy in patients with benign prostatic hyperplasia (BPH).
Lee SW   +20 more
europepmc   +2 more sources

Does treatment with dutasteride or finasteride has impact on renal morphology? Experimental study

open access: yesActa Cirúrgica Brasileira, 2021
Purpose: To investigate whether renal modifications occur following treatment with dutasteride or finasteride. Methods: Twenty-four male rats were divided into three groups: control (that received distilled water), dutasteride (0.5 mg/kg/day), and ...
Marcello Henrique Araújo da Silva   +4 more
doaj   +1 more source

Cerebral Venous Sinus Thrombosis Associated with Dutasteride Use [PDF]

open access: yes, 2020
Cerebral venous thrombosis (CVT) is an uncommon cause of stroke that mainly affects young adults with known risk factors of prothrombotic conditions, pregnancy, infection, malignancy, and drugs.
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core   +1 more source

Short course of dutasteride in treatment of a refractory category IIIB chronic prostatitis (A placebo-controlled study)

open access: yesProstate International, 2022
Objective: To evaluate the short-term efficacy of Dutasteride in the management of chronic prostatitis (CP)/chronic pelvic pain syndrome. Materials and methods: A randomized placebo-controlled double-blind study was conducted that including 50 patients ...
Ahmed Higazy   +6 more
doaj   +1 more source

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