Results 11 to 20 of about 6,946 (216)

The effects of dutasteride and tamsulosin, alone or in association, in the kidney morphology: experimental study in rats. [PDF]

Acta Cir Bras
Purpose: To evaluate the renal morphology after isolated and combined administration of dutasteride and tamsulosin in rats. Methods: Forty male rats were divided in groups: control group; D, receiving 0.5 mg/kg/day of dutasteride; T, receiving 0.4 mg/kg/
Silva MHAD, Ferreira SG, Gregório BM, Sampaio FJ, Souza DB.   +4 more
europepmc   +3 more sources

Formulation of a film-coated dutasteride tablet bioequivalent to a soft gelatin capsule (Avodart®): Effect of γ-cyclodextrin and solubilizers

Asian Journal of Pharmaceutical Sciences, 2019
The aim of this study was to optimize a tablet formulation of dutasteride that is bioequivalent to a commercially available soft gelatin capsule (Avodart®).
Dae-Duk Kim
exaly   +3 more sources

Effects of dutasteride with Bacillus Calmette-Guérin therapy on recurrence, progression, metastasis, and survival in non-muscle invasive bladder cancer: a retrospective single-center study. [PDF]

BMC Urol
Background To evaluate the impact of dutasteride, a 5-alpha reductase inhibitor, used alongside intravesical Bacillus Calmette-Guérin therapy on recurrence, progression, metastasis, and disease-free survival in non-muscle invasive bladder cancer patients.
Nebioğlu A, Başaranoğlu M, Bozlu M, Tek M, Akbay E.   +4 more
europepmc   +2 more sources

Combined therapy with dutasteride and tadalafil vs dutasteride or tadalafil monotherapy in benign prostatic hyperplasia: a randomised phase III trial. [PDF]

BJU Int
Objectives To evaluate the efficacy and safety of a fixed‐dose combination (FDC) of dutasteride and tadalafil vs monotherapy in patients with benign prostatic hyperplasia (BPH). Patients and Methods This phase III trial enrolled 667 patients. After screening and washout, eligible patients were stratified by the baseline International Prostate Symptom ...
Lee SW, Lee SH, Kim JH, Noh JH, Lee JH, Ha US, Oh CY, Kang TW, Lee G, Lee S, Han DH, Han JH, Song SH, Park HJ, Chung BH, Min GE, Jeong IG, Moon KH, Kim WT, Lee JY, Kim CS.   +20 more
europepmc   +2 more sources

Dehydroepiandrosterone Decline in Aging Males as a Predictor of Erectile Dysfunction and Mood Disorders in Patients With Benign Prostate Hyperplasia Undergoing Dutasteride Treatment. [PDF]

Am J Mens Health
Age-related decline in dehydroepiandrosterone (DHEA) and its sulfate metabolite, dehydroepiandrosterone-sulfate (DHEAS), affects steroid synthesis in men.
Glavinov MS, Tahir S, Arsov S.
europepmc   +2 more sources

The postfinasteride syndrome; an overview [PDF]

, 2016
As a 5-α reductase inhibitor, Finasteride has proven effective in ameliorating two conditions documented to be androgen dependent, namely male androgenic alopecia and benign prostatic hyperplasia. Therapeutic results are maintained as long as the drug is
Banu, Petrisor, Bălălău, Cristian, Constantin, Vlad D., Motofei, Ion G., Popa, Florian, Păunică, Georgeta P., Păunică, Ioana, Păunică, Stana, Rowland, David L., Vasilache, Adriana   +9 more
core   +10 more sources

Ameliorative potentials of Aju Mbaise extract (AME) on Dutasteride induced oxidative stress and hepatic injury in rats

Journal of Herbal Drugs, 2023
Background & Aim: Aju Mbaise is a polyherbal extract with nutraceutical properties that helps to replenish the volume of blood lost during childbirth and improves breast milk secretion and the general wellbeing of the mother.
Robert Ikechukwu Uroko, Elisha Uko Ogwo , Paul Nweje-Anyalowu , Ikenna Obiwuru, Chinomso Friday Aaron, Obinna Joseph Mba   +5 more
doaj   +1 more source

Peripheral Neuroprotective and Immunomodulatory Effects of 5α-Reductase Inhibitors in Parkinson’s Disease Models

Frontiers in Pharmacology, 2022
Gastrointestinal disorders in Parkinson’s disease (PD) have been associated with neuronal alteration in the plexus of the gut. We previously demonstrated the immunomodulatory effect of female hormones to treat enteric neurodegeneration in the 1-methyl-4 ...
Andrée-Anne Poirier, Andrée-Anne Poirier, Mélissa Côté, Hend Jarras, Hend Jarras, Nadhir Litim, Nadhir Litim, Jérôme Lamontagne-Proulx, Jérôme Lamontagne-Proulx, Sara Al-Sweidi, Sara Al-Sweidi, Marc Morissette, Asmaa Lachhab, Asmaa Lachhab, Martin Pelletier, Martin Pelletier, Thérèse Di Paolo, Thérèse Di Paolo, Denis Soulet, Denis Soulet, Denis Soulet   +20 more
doaj   +1 more source

Impact of short‐term Dutasteride treatment on prostate‐specific membrane antigen expression in a mouse xenograft model

Cancer Reports, 2021
Background Dutasteride has been shown to increase expression of the prostate‐specific membrane antigen (PSMA) in prostate cancer cells in previous in vitro studies. This 5‐alpha‐reductase inhibitor is commonly used for the treatment of symptomatic benign
Benedikt Kranzbühler, Rosa Sousa, Lukas Prause, Irene A. Burger, Niels J. Rupp, Tullio Sulser, Souzan Salemi, Daniel Eberli   +7 more
doaj   +1 more source

Transurethral Resection of Prostate and Blood loss: Efficacy of Dutasteride in reducing perioperative blood loss.

International Journal of Endorsing Health Science Research, 2021
Background: Benign Prostatic Hyperplasia (BPH) is the most common urological cause of urinary obstruction, affecting men above 50 years of age.
Shakeel Haseeb uddin Siddique, Salman El Khalid, Muhammad Shoaib Mithani, Abdul Wasay Mahmood, Shariq Anis Khan, Fakhir Yousuf   +5 more
doaj   +1 more source