Combined therapy with dutasteride and tadalafil vs dutasteride or tadalafil monotherapy in benign prostatic hyperplasia: a randomised phase III trial. [PDF]
BJU IntObjectives To evaluate the efficacy and safety of a fixed‐dose combination (FDC) of dutasteride and tadalafil vs monotherapy in patients with benign prostatic hyperplasia (BPH). Patients and Methods This phase III trial enrolled 667 patients. After screening and washout, eligible patients were stratified by the baseline International Prostate Symptom ...
Lee SW +20 more
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A Robust and Universal LC-MS/MS Method for Determination of N-Nitrosodimethylamine in Pharmaceuticals Using a C30 Column. [PDF]
J Sep SciABSTRACT Since the 2018 valsartan recall, the genotoxic impurity N‐nitrosodimethylamine (NDMA) has been frequently detected in various pharmaceuticals. Matrix variability often complicates routine testing, requiring customized analyses. We developed a universal LC–MS/MS method enabling consistent NDMA detection across diverse pharmaceuticals ...
An B +9 more
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Effect of Dutasteride on the Risk of Prostate Cancer
New England Journal of Medicine, 2010 We conducted a study to determine whether dutasteride reduces the risk of incident prostate cancer, as detected on biopsy, among men who are at increased risk for the disease.In this 4-year, multicenter, randomized, double-blind, placebo-controlled, parallel-group study, we compared dutasteride, at a dose of 0.5 mg daily, with placebo.
Andriole, G.L. +16 more
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Cerebral Venous Sinus Thrombosis Associated with Dutasteride Use [PDF]
, 2020 Cerebral venous thrombosis (CVT) is an uncommon cause of stroke that mainly affects young adults with known risk factors of prothrombotic conditions, pregnancy, infection, malignancy, and drugs.
이경열
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, 2023 Latar belakang: Obat Dutasteride tergolong dalam obat golongan keras, yang merupakan obat yang tidak boleh diberikan pada wanita dan wanita hamil memberikan cacat pada bayi laki-laki, merupakan salah satu obat yang dilarang dikonsumsi saat donor darah ...
Heni Febriani +2 more
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MRI findings in men on active surveillance for prostate cancer: does dutasteride make MRI visible lesions less conspicuous? Results from a placebo-controlled, randomised clinical trial [PDF]
, 2017 Objectives To investigate changes in the Apparent Diffusion Coefficient (ADC) using diffusion-weighted imaging (DWI) in men on active surveillance for prostate cancer taking dutasteride 0.5 mg or placebo.
Giganti, F. +12 more
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Impact of dutasteride on spermatogenesis and oxidative status in rats [PDF]
, 2020 Objectives: Although the association between 5 alpha reductase inhibitors used for the treatment of both androgenetic alopecia and benign prostatichy perplasia and their side effects is well established, the impact of dutasteride on testicular structure ...
Gül, Abdullah +6 more
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Preventive and therapeutic efficacy of finasteride and dutasteride in TRAMP mice [PDF]
, 2013 Background: The prostate cancer prevention trial (PCPT) and Reduction by dutasteride of Prostate Cancer Events (REDUCE) trial found that 5α-reductase (5αR) inhibitors finasteride and dutasteride respectively, decreased prostate cancer prevalence but also
Unis Dave +14 more
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Dutasteride and Prostate Cancer [PDF]
New England Journal of Medicine, 2010 Contains fulltext : 88812.pdf (Publisher’s version ) (Open Access)
Kiemeney, L.A.L.M., Bosland, M.C.
openaire +7 more sources
Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis? [PDF]
, 2022 Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is characterized by the loss of upper and lower motor neurons (MNs) in the cerebral cortex, brainstem and spinal cord, with consequent weakness, atrophy and the progressive paralysis
Lajara-Romance, Jose María +20 more
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