Results 21 to 30 of about 4,735 (197)

Studi Recovery Dutasteride dalam Pelarut Organik terhadap Dutasteride Terlarut dalam Plasma Darah Manusia: Study of Recovery of Dutasteride in Organic Solvents against Dutasteride Dissolved in Human Blood Plasma

, 2023
Latar belakang: Obat Dutasteride tergolong dalam obat golongan keras, yang merupakan obat yang tidak boleh diberikan pada wanita dan wanita hamil memberikan cacat pada bayi laki-laki, merupakan salah satu obat yang dilarang dikonsumsi saat donor darah ...
Heni Febriani, Khristiani, Eva Runi, Sasmita Jati, Marius Agung   +2 more
core   +1 more source

Formulation of a film-coated dutasteride tablet bioequivalent to a soft gelatin capsule (Avodart®): Effect of γ-cyclodextrin and solubilizers

Asian Journal of Pharmaceutical Sciences, 2019
The aim of this study was to optimize a tablet formulation of dutasteride that is bioequivalent to a commercially available soft gelatin capsule (Avodart®).
Mi-Hong Min, Jin-Hyong Park, Mi-Ran Choi, Jong-Hyun Hur, Byung-Nak Ahn, Dae-Duk Kim   +5 more
doaj   +1 more source

Impact of dutasteride on spermatogenesis and oxidative status in rats [PDF]

, 2020
Objectives: Although the association between 5 alpha reductase inhibitors used for the treatment of both androgenetic alopecia and benign prostatichy perplasia and their side effects is well established, the impact of dutasteride on testicular structure ...
Gül, Abdullah, Şerefoğlu, Ege Can, Özsoy, Şule, Çelik, Duygu S., Saraç, Tülin, Gül, Murat, Semerciöz, Atilla   +6 more
core   +3 more sources

The impact of finasteride and dutasteride treatments on proliferation, apoptosis, androgen receptor, 5α-reductase 1 and 5α-reductase 2 in TRAMP mouse prostates

Heliyon, 2017
Background: Previously, we studied the effect of finasteride- or dutasteride-containing diets in male C57BL/6 TRAMP x FVB mice. Pre (6 weeks of age) and post (12 weeks of age) groups received finasteride or dutasteride to determine the efficacy of these ...
Alexander B. Opoku-Acheampong, Jamie N. Henningson, Brian L. Lindshield   +2 more
doaj   +1 more source

MRI findings in men on active surveillance for prostate cancer: does dutasteride make MRI visible lesions less conspicuous? Results from a placebo-controlled, randomised clinical trial [PDF]

, 2017
Objectives To investigate changes in the Apparent Diffusion Coefficient (ADC) using diffusion-weighted imaging (DWI) in men on active surveillance for prostate cancer taking dutasteride 0.5 mg or placebo.
Giganti, F., Moore, C.M., Jameson, C., Emberton, M., Kirkham, A., Winkler, M., Whitcher, B., Castro, R., Allen, C., Bott, S.R.J., Robertson, N.L., Gambarota, G., McCartan, N.   +12 more
core   +1 more source

The role of preoperative dutasteride in reducing bleeding during transurethral resection of the prostate: A systematic review and meta-analysis of randomized controlled trials

Asian Journal of Urology, 2022
Objective: Bleeding is one of the most common complications of transurethral resection of the prostate (TURP). Several previous studies reported that administering dutasteride before surgery could reduce perioperative bleeding.
Yudhistira Pradnyan Kloping, Niwanda Yogiswara, Yusuf Azmi   +2 more
doaj   +1 more source

Free combination of dutasteride plus tamsulosin for the treatment of benign prostatic hyperplasia in South Korea: analysis of drug utilization and adverse events using the National Health Insurance Review and Assessment Service database

BMC Urology, 2021
Objective To assess the use and safety of free combination therapy (dutasteride and tamsulosin), dutasteride monotherapy, or tamsulosin monotherapy in patients with benign prostatic hyperplasia (BPH).
Zrinka Lulic, Hwancheol Son, Sang-Bae Yoo, Marianne Cunnington, Pratiksha Kapse, Diane Miller, Vanessa Cortes, Suna Park, Rachel H. Bhak, Mei Sheng Duh   +9 more
doaj   +1 more source

Controlled release of dutasteride from biodegradable microspheres: in vitro and in vivo studies. [PDF]

PLoS ONE, 2014
The aim of the present work was to study the in vitro/in vivo characteristics of dutasteride loaded biodegradable microspheres designed for sustained release of dutasteride over four weeks.
Xiangyang Xie, Yanfang Yang, Qiang Chi, ZhiPing Li, Hui Zhang, Ying Li, Yang Yang   +6 more
doaj   +1 more source

A population-based study of the risk of osteoporosis and fracture with dutasteride and finasteride

BMC Musculoskeletal Disorders, 2018
Background Dutasteride is a potent inhibitor of 5-alpha reductase enzymes that reduces concentrations of dihydrotestosterone to a greater extent than finasteride. Whether this has adverse implications for bone health is unknown.
Tony Antoniou, Erin M. Macdonald, Zhan Yao, Tara Gomes, Mina Tadrous, Joanne M.-W. Ho, Muhammad M. Mamdani, David N. Juurlink, for the Canadian Drug Safety and Effectiveness Research Network   +8 more
doaj   +1 more source

Patterns of finasteride and dutasteride use in the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial cohort: effects of socio-demographic factors and a black box warning [PDF]

Journal of Men's Health, 2022
Background: Five-alpha reductase inhibitors (5-ARIs), specifically finasteride and dutasteride, have been shown to significantly reduce prostate cancer incidence.
Jarrett A. Johnson, Paul F. Pinsky, Howard L. Parnes, Damali N. Martin   +3 more
doaj   +1 more source