Results 131 to 140 of about 15,420 (189)

Preoperative antihypertensives and hypotension during bladder tumor resection with oral 5-aminolevulinic acid administration. [PDF]

PLoS One
Kondo Y, Mihara T, Yoshikawa N, Echigo N, Nagamine Y, Goto T.   +5 more
europepmc   +1 more source

A novel acquired resistance mechanism to 5-aminolevulinic acid-mediated photodynamic therapy with ABCG2 inhibition. [PDF]

Photochem Photobiol
Chandratre S, Olsen J, Chen B.
europepmc   +1 more source

Comparison of 5-aminolevulinic acid and MMP-14 targeted peptide probes in preclinical models of GBM. [PDF]

Theranostics
Kasten BB, Dai T, Jiang K, Clements JC, Zhou K, Gallegos CA, Lee SN, Sorace AG, Houson HA, Stone LD, Markert JM, Rao J, Warram JM.   +12 more
europepmc   +1 more source

5-Aminolevulinic acid activates the MdWRKY71-MdMADS1 module to enhance anthocyanin biosynthesis in apple. [PDF]

Mol Hortic
Zhang L, Tao H, Zhang J, An Y, Wang L.
europepmc   +1 more source

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5-Aminolevulinic acid synthase: mechanism, mutations and medicine

Biochimica Et Biophysica Acta - Proteins and Proteomics, 2003
5-Aminolevulinic acid synthase (ALAS), the first enzyme of the heme biosynthesis pathway, catalyses the pyridoxal 5'-phosphate-dependent condensation between glycine and succinyl-CoA to yield 5-aminolevulinic acid (5-amino-4-oxopentanoate). A three-dimensional structural model of Rhodobacter spheroides ALAS has been constructed and used to identify ...
Ipsita Roy, Robert L Baxter, Peter M Shoolingin-Jordan   +2 more
exaly   +3 more sources

5-Aminolevulinic Acid Imaging of Malignant Glioma

Surgical Oncology Clinics of North America, 2022
High-grade glioma is the most common malignant primary brain tumor in adults. Glioma infiltration renders it difficult to treat and likely to recur. Increasing the extent of resection has been associated with improving progression-free survival and overall survival by several months. The introduction of 5-aminolevulinic acid (5-ALA) fluorescence-guided
Guan, Li, Adrian, Rodrigues, Lily, Kim, Cesar, Garcia, Shruti, Jain, Michael, Zhang, Melanie, Hayden-Gephart   +6 more
openaire   +2 more sources

The stability of 5-aminolevulinic acid in solution

Journal of Photochemistry and Photobiology B: Biology, 2002
5-Aminolevulinic acid (ALA) is being assessed for photodynamic therapy of cancer and other diseases worldwide. However, its stability properties in solution are not well understood yet. The breakdown of ALA in pH-buffered solutions was examined in this work.
Øystein Bech, Gadmar, Johan, Moan, Eldri, Scheie, Li-Wei, Ma, Qian, Peng   +4 more
openaire   +2 more sources

5-Aminolevulinic Acid, but not 5-Aminolevulinic Acid Esters, is Transported into Adenocarcinoma Cells by System BETA Transporters

Photochemistry and Photobiology, 2000
5-aminolevulinic acid (5-ALA) and its ester derivatives are used in photodynamic therapy as precursors for the formation of photosensitizers. This study relates to the mechanisms by which 5-ALA is transported into cells. The transport of 5-ALA has been studied in a human adenocarcinoma cell line (WiDr) by means of [14C]-labeled 5-ALA.
E, Rud, O, Gederaas, A, Høgset, K, Berg
openaire   +2 more sources

5-Aminolevulinic Acid-Hyaluronic Acid Complexes Enhance Skin Retention of 5-Aminolevulinic Acid and Therapeutic Efficacy in the Treatment of Hypertrophic Scar

AAPS PharmSciTech, 2022
Hypertrophic scar is a serious skin disorder, which reduces the patient's quality of life. 5-aminolevulinic acid (5-ALA)-mediated photodynamic therapy has been used to treat patients with hypertrophic scar. However, the poor skin retention of 5-ALA limited the therapeutic effect.
Liya, Yang, Huihui, Deng, Yiman, Chen, Yuling, Chen, Ling, Guo, Min, Feng   +5 more
openaire   +2 more sources