Results 111 to 120 of about 34,838 (281)

Superior Induction of Apoptosis by Blue Light Compared to Red Light Photodynamic Therapy in Cutaneous Squamous Cell Carcinoma Keratinocytes

Journal of Biophotonics, Volume 19, Issue 5, May 2026.
This study demonstrates that 5‐ALA BL PDT induces greater levels of apoptosis in SCC cells in a wavelength‐, 5‐ALA dose‐, and temperature‐dependent manner, compared to 5‐ALA RL PDT, with higher concentrations of ALA and elevated temperatures stimulating the greatest apoptotic activity.
Julia Stolyar, Margaret Kabakova, Paras Patel, Julie Saadia‐Hazkour, Evan Austin, Jared Jagdeo   +5 more
wiley   +1 more source

The Contribution to the Assignment of Defined Daily Dose (DDD) to Antineoplastic Drugs of the Italian Working Group on DDD

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Purpose To report the experience of the Italian Working Group on DDD (Ita‐DDD‐wg) in assigning DDDs to a list of antineoplastic agents. Methods Active substances from the ATC L01 group with no assigned DDD and reimbursed at least once during 2021 by the Italian Healthcare Service were identified.
Angela Boccia, Giulia Hyeraci, Anna Girardi, Rosa Gini, Gianluca Trifirò, Ylenia Ingrasciotta, Andrea Spini, Valentina Ientile, Elisabetta Poluzzi, Giampiero Mazzaglia, Ippazio Cosimo Antonazzo, Casula Manuela, Elena Tragni, Olivia Leoni, Arianna Mazzone, Michele Ercolanoni, Martina Zanforlini, Ursula Kirchmayer, Belleudi Valeria, Marco Finocchietti, Francesco Barone‐Adesi, Giuseppe Roberto   +21 more
wiley   +1 more source

Characterization of the Orphan Cytochrome P450 CYP107J1 From Bacillus subtilis Through Peroxygenase Activity Engineering

Microbial Biotechnology, Volume 19, Issue 5, May 2026.
The orphan cytochrome P450 CYP107J1 with unknown redox partners was rationally modified into H2O2‐driven form. The QE (E251Q/T252E) mutant produced valuable chemicals by simply mixing the enzyme with substrate and H2O2. ABSTRACT Cytochrome P450 monooxygenases (P450s) not only play many physiological roles in oxidative metabolism but are also promising ...
Hideki Kato, Takafumi Hashimoto, Tuhin Das, Daniel Z. Doherty, Stephen G. Bell, Toshiki Furuya   +5 more
wiley   +1 more source

Effects of single mutations on the stability of horseradish peroxidase to hydrogen peroxide [PDF]

, 2007
Horseradish peroxidase (HRP) is a commonly used enzyme in many biotechnological fields. Improvement of HRP stability would further increase its potential application range.
Arnold, Barry J. Ryan, Bateman, Borole, Ciarán Ó'Fágáin, Hernández-Ruiz, Hiner, Hiner, Hiner, Lehmann, Lei, Maniatis, Miyazaki, O'Brien, Ryan, Schmidt, Valderrama, Wang, Wanger   +18 more
core   +2 more sources

Photodynamic therapy as a new therapeutic approach of oral lichen planus [PDF]

, 2019
Oral lichen planus (OLP) is a chronic, immunologically mediated disease, defined by periods of exacerbation and quiescence. The disease is associated with a low mortality risk, but in some instances, morbidity can be important, especially in extensive ...
Georgescu, Simona Roxana, Mitran, Cristina Iulia, Mitran, Madalina Irina, Popa, Gabriela Loredana, Sarbu, Maria Isabela, Tampa, Mircea, Tocut, Sandra Milena   +6 more
core   +1 more source

Current evidence and applications of photodynamic therapy in dermatology [PDF]

, 2014
In photodynamic therapy (PDT) a photosensitizer – a molecule that is activated by light – is administered and exposed to a light source. This leads both to destruction of cells targeted by the particular type of photosensitizer, and immunomodulation ...
Lin, Jennifer Y, Wan, Marilyn T
core   +2 more sources

Augmented 5-aminolevulinic acid derived photodynamic therapy

Brain and Spine, 2022
K. Ott, E. Bunk, S. Schipmann, A. Gorji, W. Stummer, M. Schwake   +5 more
doaj   +1 more source

5-Aminolevulinic acid-based fluorescence diagnostics of cervical preinvasive changes

Medicina, 2014
The purpose of this article is to review the diagnostic possibilities of 5-aminolevulinic acid (5-ALA)-based fluorescence diagnosis of preinvasive cervical changes.
Rasa Vansevičiūtė, Jonas Venius, Simona Letautienė   +2 more
doaj   +1 more source

The Recurrence and Cosmetic Results After Topical Photodynamic Therapy [PDF]

, 2009
Background and Design: Photodynamic therapy (FDT) is a photochemotherapy modality which is used frequently and effectively in the treatment of actinic keratosis, Bowen disease and basal cell carcinomas.
Alican Kazandı, Can Ceylan, Fezal Özdemir   +2 more
core  

Photodynamic therapy of cutaneous squamous cell carcinoma

Biomedical Photonics
Photodynamic therapy has traditionally been used and approved in many countries for the treatment of intraepithelial forms of cutaneous squamous cell carcinoma and precancer – actinic keratosis and Bowen’s disease.
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj   +1 more source