Results 101 to 110 of about 13,836,709 (221)

Assessment of the efficacy and safety of auricular keloids excision followed by 5-aminolevulinic acid photodynamic therapy

Photodiagnosis and Photodynamic Therapy
Background: Auricular keloids are a significant clinical challenge, which adversely affect the life of the patient at the level of aesthetic and psychological well-being. Despite various treatment modalities, a universally effective therapy has yet to be
Ziyue Lu, Ding Zhu, Yunchuan Yang, Huiling Kou, Xinying Li, Junbo Zhang   +5 more
doaj   +1 more source

Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins

, 2008
Hepatic 5-aminolevulinic acid synthase, the first and normally rate-controlling enzyme of heme biosynthesis, is regulated by heme. One of the known mechanisms whereby increased cellular heme regulates 5-aminolevulinic acid synthase is by decreasing the ...
Pepe, Joyce A., Lambrecht, Richard W., Cable, Edward Earl, Bonkovsky, Herbert L., Gildemeister, Otto S., Donohue, Susan E.   +5 more
core   +1 more source

Synthesis of 5-aminolevulinic acid derivatives for photodynamic therapy

, 2012
The aim of the thesis was to synthesize a new derivative of 5-aminolevulinic acid, a prodrug used in current photodynamic therapy of cancer. To improve the bioavailability of 5-aminolevulinic acid the new derivative is conceived as an ester instead of an
Miceli, Claudia
core  

Influence of 5-Aminolevulinic Acid and Red Light on Collagen Metabolism of Human Dermal Fibroblasts

, 2003
Patients with localized scleroderma receiving topical photodynamic therapy with 5-aminolevulinic acid show a reduction in skin tightness, suggesting that this therapy reduces skin sclerosis.
Landthaler, Michael, Karrer, Sigrid, Weiderer, Petra, Szeimies, Rolf-Markus, Bosserhoff, Anja Kathrin   +4 more
core   +1 more source

Biallelic pathogenic hydroxymethylbilane synthase gene variants of a neurodegenerative disorder with progressive cystic leukoencephalopathy: a case report

Journal of Medical Case Reports
Background Heterozygous mutations of the hydroxymethylbilane synthase gene can lead to acute intermittent porphyria, with episodic abdominal pain and neuropsychiatric symptoms.
Gabriel Schacht, Miriam Elbracht, Anna-Elisabeth Minder, Thomas Stauch, Arzu Stoppe, Eva Lausberg, Martin Häusler   +6 more
doaj   +1 more source

Protoporphyrin IX-Dependent Antiviral Effects of 5-Aminolevulinic Acid against Feline Coronavirus Type II

Viruses
5-Aminolevulinic acid (5-ALA), a non-proteinogenic amino acid, is an intermediate in the biosynthesis of heme and exerts antiviral effects against feline coronavirus (FCoV); however, the underlying mechanisms remain unclear.
Tomoyoshi Doki, Junna Shimada, Misa Tokunaga, Kaito To, Koichi Orino, Tomomi Takano   +5 more
doaj   +1 more source

Some reactions of 5-aminolevulinic acid with cyclic beta-diketones

, 1998
5-Aminolevulinic acid reacts, under acidic conditions, with cyclohexane-1,3-diones to give 3-(2'-carboxyethyl)tetrahydroindol-4-ones which were characterised, in part, by 2D NMR spectroscopy.
Brown, E H, Butler, A R
core   +2 more sources

aminolevulinic acid marked glioblastoma detection

, 2014
Photobleaching behavior of protoporphyrin IX during 5-aminolevulinic acid marked glioblastoma ...
Neda Haj-hosseini, Johan Richtera, Karin Wårdell, Stefan Andersson-engels   +3 more
core  

Enhanced accumulation of protoporphyrin IX via SLC6A6 and SLC36A1 sensitizes cisplatin-resistant cells to 5-aminolevulinic acid-based photodynamic therapy

Photodiagnosis and Photodynamic Therapy
Photodynamic therapy (PDT) using 5-aminolevulinic acid (5-ALA) is a promising treatment for cancer cells. Although cisplatin (CDDP) is a potent anticancer drug, acquired resistance often limits its clinical efficacy.
Sayo Horibe, Toru Tanaka, Shoji Kawauchi, Naoto Sasaki, Yoshiyuki Rikitake   +4 more
doaj   +1 more source

THE EFFECT OF PENTAKEEP®-V APPLICATION ON FLOWER TRAITS AND NECTAR PRODUCTION IN Hosta TRATT. ‘KROSSA REGAL’

Acta Scientiarum Polonorum: Hortorum Cultus, 2016
In modern horticulture the use of biostimulators for obtaining the maximum yields and qualities of the crops is favoured. Pentakeep®-V, the fertilizer containing 5-aminolevulinic acid (ALA) is currently recommended.
Bożena Denisow, Monika Strzałkowska-Abramek, Elzbieta Pogroszewska, Halina Laskowska   +3 more
doaj