Results 171 to 180 of about 21,523 (223)
Some of the next articles are maybe not open access.
New metabolites of the drug 5-aminosalicylic acid. I:N-β-D-glucopyranosyl-5-aminosalicylic acid
Xenobiotica, 19891. A new unstable metabolite of 5-aminosalicylic acid (5-ASA) was found in plasma from healthy volunteers dosed with 5-ASA i.v. 2. The metabolite was prepared by incubation of 5-ASA with rat liver homogenate, and isolated using preparative h.p.l.c. 3. The metabolite was identified as N-beta-D-glucopyranosyl-5-aminosalicylic acid by n.m.r.
J, Tjørnelund, S H, Hansen, C, Cornett
openaire +2 more sources
Inhibition of Antibody Secretion by 5-Aminosalicylic Acid
Gastroenterology, 1989We have examined the effects of sulfasalazine and its metabolites sulfapyridine and 5-aminosalicylic acid on antibody secretion by normal peripheral blood and intestinal mononuclear cells. Sulfasalazine and 5-aminosalicylic acid both inhibited pokeweed mitogen-stimulated secretion of immunoglobulins (Igs) A, G, and M by peripheral blood mononuclear ...
R P, MacDermott +5 more
openaire +2 more sources
Acute pancreatitis during oral 5-aminosalicylic acid therapy
Digestive Diseases and Sciences, 1990Therapy with oral 5-aminosalicylic acid for inflammatory bowel disease has been reported as effective and safe. We report two cases of biochemically proven mild acute pancreatitis occurring 2 and 14 days, respectively, after oral 5-aminosalicylic acid therapy was instituted for inflammatory bowel disease. A hypersensitivity mechanism might be involved,
M T, Fiorentini +4 more
openaire +2 more sources
Electrical, enzymatic graphene biosensing of 5-aminosalicylic acid
The Analyst, 2013We present an electrical biosensing of 5-aminosalicylic acid (5-ASA) based on a peroxidase-immobilized graphene sensor on a microfluidic paper. The sensor shows a sensitive detection range from 0.5 to 20 μM and a total measuring time of 2 min with a simple fabrication procedure.
Pratima, Labroo, Yue, Cui
openaire +2 more sources
Pancreatitis After Rectal Administration of 5-Aminosalicylic Acid
Journal of Clinical Gastroenterology, 1990A patient treated with sulfasalazine for new-onset ulcerative colitis developed self-limited pancreatitis. Rechallenge with 5-aminosalicylic acid (5-ASA) in enema form (Rowasa) again induced pancreatitis. Recent case reports suggest that the salicylate component of sulfasalazine can lead to the development of pancreatitis with oral 5-ASA administration.
K L, Isaacs, D, Murphy
openaire +2 more sources
5-Aminosalicylic Acid and Chemoprevention: Does It Work?
Digestive Diseases, 20135-Aminosalicylic acid (5-ASA)-containing drugs are the mainstay of therapy in inflammatory bowel disease (IBD). Intestinal inflammation is the main risk factor for colorectal cancer (CRC) in IBD. Hence, all drugs that are able to induce and maintain mucosal healing (MH) may prevent CRC risk in IBD.
Lopez, Anthony, Peyrin-Biroulet, Laurent
openaire +2 more sources
Chronic Interstitial Nephritis due to 5-Aminosalicylic Acid
American Journal of Nephrology, 1999Nephrotoxicity has recently been reported with the use of 5-aminosalicylic acid (5-ASA) which has structural similarities to phenacetin and aspirin. The present paper describes 2 cases of interstitial nephritis and 1 case of end-stage failure associated with 5-ASA treatment.
M, Agharazii +4 more
openaire +2 more sources
The anti-oxidant properties of 5-aminosalicylic acid
Free Radical Biology and Medicine, 1996Oxidative damage to biological membranes is an important cause of tissue injury in inflammatory bowel disease. 5-Aminosalicylic Acid (5ASA) has therapeutic efficacy in Ulcerative colitis, which may be based on its antioxidant properties. We used Parinaric acid as a fluorescent marker of oxidation in an intestinal microvillous brush border membrane ...
D C, Pearson +2 more
openaire +2 more sources
Baboon syndrome from 5‐aminosalicylic acid
Contact Dermatitis, 2002Gallo R, PARODI, AURORA
openaire +3 more sources