정신분열병에서의 대뇌신경전달물질에 관한 많은 연구가 있어 왔으며 도파민과 세로토닌이 대표적인 경우이다. 세로토닌 재흡수 억제제가 치료저항성 정신분열병 환자에게 임상적 효과가 있다고 알려져있다. 특히 sertraline과 같은 세로토닌 계통의 약물사용은 대뇌신경전달물질의 생화학적인 체계에 변화를 주어 치료적 효과를 나타낼 수 있다.
박병희
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Effects of vitamin D3 supplementation on clinical symptoms, quality of life, serum serotonin (5-hydroxytryptamine), 5-hydroxy-indole acetic acid, and ratio of 5-HIAA/5-HT in patients with diarrhea-predominant irritable bowel syndrome: A randomized clinical trial. [PDF]
Khalighi Sikaroudi M +8 more
europepmc +1 more source
Reduced gut microbiota-derived indole-3-carboxaldehyde and 5-hydroxyindole-3-acetic acid are associated with intestinal barrier dysfunction and inflammation in diarrheic suckling lambs. [PDF]
Li J +6 more
europepmc +1 more source
Pregnancy in a patient with metastatic functioning midgut neuroendocrine tumor receiving lanreotide after peptide receptor radionuclide therapy. [PDF]
Silva BTD +9 more
europepmc +1 more source
Modulation of Leptin and Serotonin by Honey and Its Glycoproteins Against High-Fat Diet-Induced Metabolic and Anxiety Phenotypes. [PDF]
Gohar A +5 more
europepmc +1 more source
Diminished Maternal Tryptophan Leads to Sexually Dimorphic Differences in the Placenta-Brain Axis. [PDF]
Herrington RTB +10 more
europepmc +1 more source
Optimization and Validation of Plasma-Based Assay for Detection and Quantification of Monoamine Neurotransmitter Metabolites Using LC-MS/MS. [PDF]
Tauro L +5 more
europepmc +1 more source
High social jetlag in healthy youth: differences in tryptophan levels and regional gray matter volume. [PDF]
Yamashita M +6 more
europepmc +1 more source
Spatial Metabolomics Reveals Microregion-Specific Neurochemical Perturbations in the Brains of PCPA-Induced Insomniac Rats: Integration of MALDI-MSI and Targeted LC-MS/MS. [PDF]
Yan Y +7 more
europepmc +1 more source

