Results 141 to 150 of about 125,938 (267)

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Limited Associations Between 5-HT Receptor Gene Polymorphisms and Treatment Response in Antidepressant Treatment-Free Patients With Depression. [PDF]

Front Pharmacol, 2019
Ochi T, Vyalova NM, Losenkov IS, Paderina DZ, Pozhidaev IV, Loonen AJM, Simutkin GG, Bokhan NA, Ivanova SA, Wilffert B.   +9 more
europepmc   +1 more source

Correction: Structure-Activity Relationships of Constrained Phenylethylamine Ligands for the Serotonin 5-HT₂Receptors

, 2014
Vignir Ísberg, James Paine, Sebastian Leth‐Petersen, Jesper L. Kristensen, David E. Gloriam   +4 more
openalex   +2 more sources

N-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT₂Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues [PDF]

, 2014
David E. Nichols, Maria F. Sassano, Adam L. Halberstadt, Landon M. Klein, Simon D. Brandt, Simon Elliott, Wolfgang Fiedler   +6 more
openalex   +1 more source

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

Transcriptomic mapping of the 5-HT receptor landscape. [PDF]

Patterns (N Y)
De Filippo R, Schmitz D.
europepmc   +1 more source

Structural insight into the serotonin (5-HT) receptor family by molecular docking, molecular dynamics simulation and systems pharmacology analysis. [PDF]

Acta Pharmacol Sin, 2019
Wang YQ, Lin WW, Wu N, Wang SY, Chen MZ, Lin ZH, Xie XQ, Feng ZW.   +7 more
europepmc   +1 more source

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

Advanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen, Shuyang Yao, Sihui Cheng, Jiayi Tian, Ang Li, Yusen Yan, Xiang Zhang, Yuanjing Liu, Yumeng Wang, Qichen Cao, Chenglin Miao   +10 more
wiley   +1 more source

Distinct 5-HT receptor subtypes regulate claustrum excitability by serotonin and the psychedelic, DOI. [PDF]

Prog Neurobiol
Anderson TL, Keady JV, Songrady J, Tavakoli NS, Asadipooya A, Neeley RE, Turner JR, Ortinski PI.   +7 more
europepmc   +1 more source