Results 1 to 10 of about 9,970,544 (261)

Tablet of Spondias mombin L. Developed from Nebulized Extract Prevents Gastric Ulcers in Mice via Cytoprotective and Antisecretory Effects

open access: yesMolecules, 2021
Spondias mombin L. (Anacardiaceae) has a worldwide distribution and is present in all regions of Brazil. Its leaves, flowers and bark are used as teas in folk medicine to treat diseases of the digestive system.
Maria Elaine Araruna   +10 more
doaj   +1 more source

Formulation of functional crackers enriched with fermented soybean (tempeh) paste: rheological and microstructural properties

open access: yesFuture Foods, 2021
This study focused on the physicochemical properties and sensorial attributes of tempeh paste (TP) incorporated with wheat flour (WF) and soy protein isolate (SPI).
Tan Zhi Hui Nicole   +3 more
doaj   +1 more source

Comparison of Hydroxypropylcellulose and Hot-Melt Extrudable Hypromellose in Twin-Screw Melt Granulation of Metformin Hydrochloride: Effect of Rheological Properties of Polymer on Melt Granulation and Granule Properties

open access: yesMacromol, 2021
High-molecular-weight hypromellose (HPMC) and hydroxypropyl cellulose (HPC) are widely known, extended-release polymers. Conventional high-molecular-weight HPMCs are preferred in extended-release applications but not widely used in twin-screw melt ...
Amol Batra   +9 more
doaj   +1 more source

SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon

open access: yesCells, 2021
Alternative splicing (AS) is an important posttranscriptional regulatory process. Damaged or unnecessary cells need to be removed though apoptosis to maintain physiological processes. Caspase-2 pre-mRNA produces pro-apoptotic long mRNA and anti-apoptotic
Jiyeon Ha   +11 more
doaj   +1 more source

U2AF65-Dependent SF3B1 Function in SMN Alternative Splicing

open access: yesCells, 2020
Splicing factor 3b subunit 1 (SF3B1) is an essential protein in spliceosomes and mutated frequently in many cancers. While roles of SF3B1 in single intron splicing and roles of its cancer-linked mutant in aberrant splicing have been identified to some ...
Namjeong Choi   +5 more
doaj   +1 more source

hnRNP A1 Regulates Alternative Splicing of Tau Exon 10 by Targeting 3′ Splice Sites

open access: yesCells, 2020
The ratio control of 4R-Tau/3R-Tau by alternative splicing of Tau exon 10 is important for maintaining brain functions. In this study, we show that hnRNP A1 knockdown induces inclusion of endogenous Tau exon 10, conversely, overexpression of hnRNP A1 ...
Yongchao Liu   +7 more
doaj   +1 more source

Development, validation, and application of an ultra-high performance liquid chromatography-tandem mass spectrometry method for the estimation of Ropanicant in human plasma and urine

open access: yesJournal of Chromatography Open, 2023
SUVN-911 (Ropanicant) is a novel alpha-4 beta-2 nicotinic acetylcholine receptor (α4β2 nAChR) antagonist being developed for the treatment of major depressive disorders (MDD).
Ramakrishna Nirogi   +7 more
doaj   +1 more source

Activation of Cryptic 3′ Splice-Sites by SRSF2 Contributes to Cassette Exon Skipping

open access: yesCells, 2019
Here we show that the serine/arginine rich splicing factor 2 (SRSF2) promotes cryptic 3′ splice-site (3′AG′) usage during cassette exon exclusion in survival of motor neuron (SMN2) minigenes.
Heegyum Moon   +7 more
doaj   +1 more source

Overexpression of Arabidopsis AnnAt8 Alleviates Abiotic Stress in Transgenic Arabidopsis and Tobacco

open access: yesPlants, 2016
Abiotic stress results in massive loss of crop productivity throughout the world. Because of our limited knowledge of the plant defense mechanisms, it is very difficult to exploit the plant genetic resources for manipulation of traits that could benefit ...
Deepanker Yadav   +4 more
doaj   +1 more source

TonB-Dependent Transporters in Sphingomonads: Unraveling Their Distribution and Function in Environmental Adaptation

open access: yesMicroorganisms, 2020
TonB-dependent transport system plays a critical role in the transport of nutrients across the energy-deprived outer membrane of Gram-negative bacteria.
Devyani Samantarrai   +3 more
doaj   +1 more source

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