Results 31 to 40 of about 9,896,464 (337)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

500 Kilovolt Cathode Rays [PDF]

open access: yes, 1931
The high potential x-ray tube at the California Institute has been modified so as to permit either x-rays or cathode rays to be produced. Electron currents up to 35 microamperes have been obtained through an aluminum window.
Vollrath, R. E.
core  

Andreas Vesalius: Celebrating 500 years of dissecting nature [PDF]

open access: yes, 2015
December 31st, 2014 marked the 500-year anniversary of the birth of Andreas Vesalius. Vesalius, considered as the founder of modern anatomy, had profoundly changed not only human anatomy, but also the intellectual structure of medicine. The impact of his
Elmaghawry, Mohamed   +3 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Tanzania Joint Health Technical Review 2002:final report HIV/AIDS [PDF]

open access: yes, 2002
\ud Tanzania has a HIV epidemic at an estimated range of approximately 12% of the adult population (15-49 years) being infected. The epidemic is still increasing and there are few signs that the epidemic will level off in the near future.
Alban, Anita, Kimambo, Adeline
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Ixiptla

open access: yesPitágoras 500, 2019
Danièle Dehouve, no estudo El papel de la vestimenta en los rituales mexicas de ‘personificación’, propõe que a palavra náhuatl ixiptla seja traduzida como “cobrir-se com os ornamentos de um deus e ver, ouvir e falar com ele”.
Sandra Regina Facioli Pestana   +1 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

O treinamento do ator no laboratório de criação e investigação da cena contemporânea

open access: yesPitágoras 500, 2019
Investiga-se uma metodologia para o aprendizado da arte do ator, mais afim a um dispositivo de treinamento pela via da respiração, desvinculada de uma formalidade acadêmica tradicional.
Martha de Mello Ribeiro
doaj   +1 more source

Série Aquilombô e a publicação como resistência negra

open access: yesPitágoras 500, 2020
Este artigo tem, por objetivo, apresentar a Série Editorial Aquilombô, uma atividade do Fórum Permanente das Artes Negras – Aquilombô. Trata-se de um trabalho de caráter panorâmico, em que são abordados os seguintes pontos: o conceito de quilombo e sua ...
Marcos Fábio Cardoso de Faria
doaj   +1 more source

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