Results 211 to 220 of about 1,554,548 (330)

510. Analysis of Adenoviral Vector Stability in the Presence of Di(2-ethylhexyl) Phthalate (DEHP), a Common Plasticizer Found in Injection Catheters [PDF]

, 2003

openalex   +1 more source

Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis

Advanced Science, EarlyView.
This study demonstrates that hyperglycemia in diabetes activates ChREBP, which epigenetically represses SCAMP5 expression in pancreatic β‐cells. This SCAMP5 deficiency impairs insulin secretion by downregulating the calcium channel CaV1.2. Furthermore, reduced SCAMP5 triggers β‐cell apoptosis by stabilizing VDAC1 and enhancing its interaction with Bax,
Yingqi Zhang, Donglan Tang, Chenxi Yang, Chao Lin, Yingyue Yuan, Meiying He, Yiying Chen, Zhuo Mao, Ying Ying, Xiaosong Ma, Xiangchen Kong   +10 more
wiley   +1 more source

Udział Archiwum Narodowego w Krakowie w konkursie programistycznym Coding da Vinci Ost3 2022

Krakowski Rocznik Archiwalny, 2023
Anna Sokół, Aldona Warzecha
doaj   +1 more source

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

Advanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao, Pingying Qing, Hanxiao Chen, Zhengyan Hu, Qiaoran Yang, Chenyang Lu, Huimin Liu, Rujun Zeng, Yuanting Tang, Fan Yu, Jinbiao Han, Xin Liao, Xun Zeng, Lang Qin   +13 more
wiley   +1 more source

510 Numerical Simulation of Gravity Currents by the Finite Difference Lattice Boltzmann Method

, 2001
Minoru Watari, Ho Kuen KANG, Michihisa Tsutahara   +2 more
openalex   +2 more sources

Amino Acids 270 to 510 of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein Are Required for Interaction with Receptor [PDF]

, 2004
Gregory J. Babcock, Diana J. Esshaki, William D. Thomas, Donna M. Ambrosino   +3 more
openalex   +1 more source

Hepatic ENTPD5 Is Critical for Maintaining Metabolic Homeostasis and Promoting Brown Adipose Tissue Thermogenesis

Advanced Science, EarlyView.
ENTPD5‐mediated conversion of extracellular adenosine triphosphate to ADP of hepatocytes is critical for maintaining hepatic glucose/lipid metabolism and promoting brown adipose tissue thermogenesis via the inhibition of adrenomedullin expression and secretion.
Rufeng Ma, Song Hou, Rui Xiang, Wenjun Liu, Xin Li, Yujing Chi, Ming Xu, Haochen Yao, Jing Li, Jichun Yang   +9 more
wiley   +1 more source

510 Numerical Analysis of the Flow Field around a Staggered Tube Bundle

, 2001
Manami Nakamura, Hiroki Tanaka, Fumio SHIMIZU   +2 more
openalex   +2 more sources

510. In Vivo-Gene Expression of Aerosolized PEI Gene Vector Complexes Is Solvent-Dependent [PDF]

, 2004
Carsten Rudolph, Aurora Ortiz, Ulrike Schillinger, Christian Plank, Joseph Rosenecker   +4 more
openalex   +1 more source

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

Advanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu, Xiaobei Wang, Parker Mathews, Shaima Jabbar, Min Zhang, Haim Moskowitz, Wei Duan, David P. Nichols, George William Schaaf, John D. Olson, Andrew N. Macintyre, J. Daniel Bourland, Ivan Spasojevic, Jen‐Tsan Ashley Chi, Joel Ross, Nelson Chao, J. Mark Cline, Peter B. Heifetz, Yubin Kang   +18 more
wiley   +1 more source