Results 21 to 30 of about 246,229 (319)

Visualization of the radiofrequency lesion after pulmonary vein isolation using delayed enhancement magnetic resonance imaging fused with magnetic resonance angiography

open access: yesJournal of Arrhythmia, 2015
Background: The radiofrequency (RF) lesions for atrial fibrillation (AF) ablation can be visualized by delayed enhancement magnetic resonance imaging (DE-MRI).
Kunihiko Kiuchi, MD   +22 more
doaj   +1 more source

Impact of esophageal temperature monitoring guided atrial fibrillation ablation on preventing asymptomatic excessive transmural injury

open access: yesJournal of Arrhythmia, 2016
Background: Even with the use of a reduced energy setting (20–25 W), excessive transmural injury (ETI) following catheter ablation of atrial fibrillation (AF) is reported to develop in 10% of patients.
Kunihiko Kiuchi, MD, FHRS   +31 more
doaj   +1 more source

Visualizing radiofrequency lesions using delayed-enhancement magnetic resonance imaging in patients with atrial fibrillation: A modification of the method used by the University of Utah group

open access: yesJournal of Arrhythmia, 2015
Background: Atrial tissue fibrosis has previously been identified using delayed-enhancement MRI (DE-MRI) in patients with atrial fibrillation (AF). Although the clinical importance of DE-MRI is well recognized, the visualization of atrial fibrosis and ...
Kunihiko Kiuchi, MD   +22 more
doaj   +1 more source

Improved Manufacturability and In Vivo Comparative Pharmacokinetics of Dapagliflozin Cocrystals in Beagle Dogs and Human Volunteers

open access: yesPharmaceutics, 2021
Dapagliflozin (DAP), which improves glycemic control in patients with type 2 diabetes mellitus, has poor physical properties against heat and moisture, thus hindering its manufacturing potential.
Sangho Cho   +5 more
doaj   +1 more source

Atypically Shaped Cardiomyocytes (ACMs): The Identification, Characterization and New Insights into a Subpopulation of Cardiomyocytes

open access: yesBiomolecules, 2022
In the adult mammalian heart, no data have yet shown the existence of cardiomyocyte-differentiable stem cells that can be used to practically repair the injured myocardium.
Mariko Omatsu-Kanbe   +3 more
doaj   +1 more source

Phosphatidylinositol4-phosphate 5-kinase prevents the decrease in the HERG potassium current induced by Gq protein-coupled receptor stimulation

open access: yesJournal of Pharmacological Sciences, 2015
The human ether-a-go-go-related gene (HERG) potassium current (IHERG) has been shown to decrease in amplitude following stimulation with Gq protein-coupled receptors (GqRs), such as α1-adrenergic and M1-muscarinic receptors (α1R and M1R, respectively ...
Taeko Kubo   +5 more
doaj   +1 more source

A 520 million-year-old chelicerate larva [PDF]

open access: yesNature Communications, 2014
An important survival strategy for animal species is the so-called niche differentiation between larva and adult. Different developmental stages of the same animal occupy different ecological niches to avoid competing for food or other essential resources.
Carolin Haug   +5 more
openaire   +4 more sources

Glycaemia and body weight are regulated by sodium-glucose cotransporter 1 (SGLT1) expression via O-GlcNAcylation in the intestine

open access: yesMolecular Metabolism, 2022
Objective: The intestine is an important organ for nutrient metabolism via absorption and endocrine systems. Nutrients regulate O-GlcNAcylation, a post-translational modification of various proteins by O-GlcNAc transferase (OGT). We have previously shown
Kimihiro Nishimura   +12 more
doaj  

The Value of Interleukin-6 among Several Inflammatory Markers as a Predictor of Respiratory Failure in COVID-19 Patients

open access: yesDiagnostics, 2021
Patients with coronavirus disease 2019 (COVID-19) develop severe respiratory failure within a short period during the clinical course. It is essential to predict respiratory deterioration in the short term. We investigated the use of inflammatory markers
Mitsuhiro Fujino   +5 more
doaj   +1 more source

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