Results 51 to 60 of about 1,558,250 (328)

The conundrum of categorising requirements: managing requirements for learning on the move [PDF]

, 2004
This paper reports on the experience of eliciting and managing requirements on a large European-based multinational project, whose purpose is to create a system to support learning using mobile technology. The project used the socio-cognitive engineering
Haley, Debra, Nuseibeh, Bashar, Sharp, Helen, Taylor, Josie   +3 more
core  

CALIPSO Lidar Calibration at 532 nm: Version 4 Nighttime Algorithm.

Atmospheric Measurement Techniques, 2018
Data products from the Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) on board Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) were recently updated following the implementation of new (version 4) calibration ...
J. Kar, M. Vaughan, Kam-Pui Lee, J. Tackett, M. Avery, A. Garnier, B. Getzewich, W. Hunt, D. Josset, Zhaoyan Liu, P. Lucker, B. Magill, A. Omar, J. Pelon, R. Rogers, T. Toth, C. Trepte, J. Vernier, D. Winker, S. Young   +19 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Tools, Technologies and Frameworks for Digital Twins in the Oil and Gas Industry: An In-Depth Analysis

Sensors
The digital twin (DT), which involves creating a virtual replica of a physical asset or system, has emerged as a transformative set of tools across various industries.
Edwin Benito Mitacc Meza, Dalton Garcia Borges de Souza, Alessandro Copetti, Ana Paula Barbosa Sobral, Guido Vaz Silva, Iara Tammela, Rodolfo Cardoso   +6 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Pharmacological Characterization of FR194921, a New Potent, Selective, and Orally Active Antagonist for Central Adenosine A1 Receptors

Journal of Pharmacological Sciences, 2004
Adenosine A1 receptors in the brain are believed to play an important role in brain functioning. We have discovered a novel adenosine A1 receptor antagonist, FR194921 (2-(1-methyl-4-piperidinyl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-3(2H)-pyridazinone),
Takuya Maemoto, Miho Tada, Takuma Mihara, Noriko Ueyama, Hideaki Matsuoka, Katsuya Harada, Takayuki Yamaji, Kiyoharu Shirakawa, Satoru Kuroda, Atsushi Akahane, Akinori Iwashita, Nobuya Matsuoka, Seitaro Mutoh   +12 more
doaj   +1 more source

RETRACTED ARTICLE: LINC01410-miR-532-NCF2-NF-kB feedback loop promotes gastric cancer angiogenesis and metastasis

Oncogene, 2018
Dysregulation of non-coding RNAs, including miRNAs and lncRNAs has been reported to play vital roles in gastric cancer (GC) carcinogenesis, but the mechanism involved is largely unknown.
Jiaxing Zhang, Zhen-hua Chen, Dong‐Liang Chen, X. Tian, Chenyuan Wang, Zhiyou Zhou, Ying Gao, Yi Xu, Cui P. Chen, Zhou-san Zheng, H. Weng, S. Ye, M. Kuang, D. Xie, S. Peng   +14 more
semanticscholar   +1 more source

Long noncoding RNA VPS9D1-AS1 augments the malignant phenotype of non-small cell lung cancer by sponging microRNA-532-3p and thereby enhancing HMGA2 expression

Aging, 2020
We investigated the influence of the long noncoding RNA VPS9D1 antisense RNA 1 (VPS9D1-AS1) on the malignant phenotype of non-small cell lung cancer (NSCLC) cells in vitro and in vivo.
Xiao Han, Tianren Huang, Jun-qing Han
semanticscholar   +1 more source

Duplex Stainless Steel Laser‐Surface Textured: Stability in Brine Solution

Advanced Engineering Materials, EarlyView.
Controlled laser‐surface treatment (LST) of duplex DSS2205 steel is performed to increase its stability in brine solution under cyclic electrochemical assays. The superior protection with respect to flat and smooth panels is attributed to the presence of FeCr2O4 as the main protective oxide layer in the LST surface, after corrosion tests. The stability
Mohammad Rezayat, Hamidreza Enshaei, Elaine Armelin, José I. Iribarren, Antonio Mateo, Miguel Morales   +5 more
wiley   +1 more source

Reinventing Central Office [PDF]

, 1995
This report presents a provocative description of a school system where resources, authority, and accountability reside primarily at the school ...
Diana Lauber, Heather Lewis, Michelle Fine, Norm Fruchter, Robert Berne, Robert Palaich, Tenley Stillwell   +6 more
core