Results 1 to 10 of about 108 (87)

Overexpression of miR-532-5p restrains oxidative stress response of chondrocytes in nontraumatic osteonecrosis of the femoral head by inhibiting ABL1

Open Medicine (Poland)
This study is to probe into the meaning of serum miR-532-5p in nontraumatic osteonecrosis of the femoral head (ONFH), and a molecular mechanism of miR-532-5p in the development of nontraumatic ONFH.
Peng Shang
exaly   +2 more sources

Selection of reference genes for quantitative analysis of microRNA expression in three different types of cancer.

PLoS ONE, 2022
MicroRNAs (miRNAs) are promising biomarkers in cancer research. Quantitative PCR (qPCR), also known as real-time PCR, is the most frequently used technique for measuring miRNA expression levels.
Yuliya A Veryaskina, Sergei E Titov, Mikhail K Ivanov, Pavel S Ruzankin, Anton S Tarasenko, Sergei P Shevchenko, Igor B Kovynev, Evgenij V Stupak, Tatiana I Pospelova, Igor F Zhimulev   +9 more
doaj   +2 more sources

The prognostic miR-532-5p-correlated ceRNA-mediated lipid droplet accumulation drives nodal metastasis of cervical cancer

Journal of Advanced Research, 2022
Introduction: The prognosis for cervical cancer (CC) patients with lymph node metastasis (LNM) is extremely poor. Lipid droplets (LDs) have a pivotal role in promoting tumor metastasis.
Chunliang Shang, Yuan Li, Tianhui He, Yuandong Liao, Qiqiao Du, Pan Wang, Jie Qiao, Hongyan Guo   +7 more
doaj   +1 more source

MicroRNA-532-5p is implicated in the regulation of osteoporosis by forkhead box O1 and osteoblast differentiation

BMC Musculoskeletal Disorders, 2020
Background MicroRNAs (miRNAs) are critical regulators in osteogenesis and cartilage formation. This study was designed to investigate whether miR-532-5p plays a role in the regulation of osteoporosis.
Xinyu Guo, Shijun Wei, Feng Xu, Xianhua Cai, Huasong Wang, Ran Ding   +5 more
doaj   +1 more source

lncRNA ACTA2-AS1 predicts malignancy and poor prognosis of triple-negative breast cancer and regulates tumor progression via modulating miR-532-5p

BMC Molecular and Cell Biology, 2022
Background Dysregulation of ACTA2-AS1 and miR-532-5p and their functions in various cancers have been widely reported. Their potential of serving as biomarkers in triple-negative breast cancer (TNBC) remains unknown.
Yi Peng, Xiaoxi Huang, Hongmei Wang
doaj   +1 more source

Serum Expression Levels of Certain miRNAs in Predicting Diagnosis, Prognosis, and Response to Chemotherapy in Malignant Pleural Mesothelioma

Balkan Medical Journal, 2022
Background: miRNAs are involved in tumor pathogenesis and can therefore be determined in the primary tumor, plasma and serum, and body fluids. As in various cancers, their role in the diagnosis, prognosis, and treatment of patients with malignant pleural
Muzaffer Metintaş, Güntülü Ak, Cansu Özbayer, Filiz Boğar, Selma Metintaş   +4 more
doaj   +1 more source

The diagnostic value of circulating miR-532-5p in patients with asymptomatic carotid artery stenosis and its predictive significance for the occurrence of cerebral ischaemic events

Archives of Medical Science, 2020
Introduction Circulating microRNAs (miRNAs) are widely identified as promi­sing and novel biomarkers for the diagnosis of human diseases. This study investigated the clinical value of miR-532-5p for asymptomatic carotid artery stenosis (CAS) patients and
Deyong Du, Jing Liu, Chengcheng Liu, Zefu Li, Yang Gao, Wensheng Zhang, Haitao Zhang   +6 more
doaj   +1 more source

MicroRNA‐532‐5p is a prognostic marker and inhibits the aggressive phenotypes of osteosarcoma through targeting CXCL2

Kaohsiung Journal of Medical Sciences, 2020
The dysregulation of miR‐532‐5p is involved in the development of several cancers. Nevertheless, the roles of miR‐532‐5p in osteosarcoma (OS) have yet to be illuminated.
Yong Ma, Hai‐Xia Zhao, Yin‐Ju Shi, Ming‐Guo Cheng   +3 more
doaj   +1 more source

Visceral Adipose Tissue of Prediabetic and Diabetic Females Shares a Set of Similarly Upregulated microRNAs Functionally Annotated to Inflammation, Oxidative Stress and Insulin Signaling

Antioxidants, 2021
Hypertrophic and hypoxic visceral adipose tissue (VAT) secretes proinflammatory cytokines promoting insulin resistance (IR), prediabetes and type 2 diabetes (T2DM) microRNAs (miRNAs) are markers of metabolic disorders regulating genes critical for e.g ...
Justyna Strycharz, Adam Wróblewski, Andrzej Zieleniak, Ewa Świderska, Tomasz Matyjas, Monika Rucińska, Lech Pomorski, Piotr Czarny, Janusz Szemraj, Józef Drzewoski, Agnieszka Śliwińska   +10 more
doaj   +1 more source

Cigarette Smoking Alters the Expression of Circulating microRNAs and Its Potential Diagnostic Value in Female Lung Cancer Patients

Biology, 2021
Cigarette smoking is a known risk factor for the development of lung cancer. We investigated whether circulating microRNA expression levels and their potential diagnostic value are affected by cigarette smoking in adenocarcinoma (AD) patients and healthy
Eric Gustavo Ramírez-Salazar, Luis Vicente Gayosso-Gómez, Renata Baez-Saldaña, Ramcés Falfán-Valencia, Rogelio Pérez-Padilla, Anjarath L. Higuera-Iglesias, María E. Vázquez-Manríquez, Blanca Ortiz-Quintero   +7 more
doaj   +1 more source