Results 1 to 10 of about 4,435 (163)

The prognostic miR-532-5p-correlated ceRNA-mediated lipid droplet accumulation drives nodal metastasis of cervical cancer [PDF]

Journal of Advanced Research, 2022
Introduction: The prognosis for cervical cancer (CC) patients with lymph node metastasis (LNM) is extremely poor. Lipid droplets (LDs) have a pivotal role in promoting tumor metastasis.
Chunliang Shang, Yuan Li, Tianhui He, Yuandong Liao, Qiqiao Du, Pan Wang, Jie Qiao, Hongyan Guo   +7 more
doaj   +4 more sources

lncRNA ACTA2-AS1 predicts malignancy and poor prognosis of triple-negative breast cancer and regulates tumor progression via modulating miR-532-5p [PDF]

BMC Molecular and Cell Biology, 2022
Background Dysregulation of ACTA2-AS1 and miR-532-5p and their functions in various cancers have been widely reported. Their potential of serving as biomarkers in triple-negative breast cancer (TNBC) remains unknown.
Yi Peng, Xiaoxi Huang, Hongmei Wang
doaj   +4 more sources

The diagnostic value of circulating miR-532-5p in patients with asymptomatic carotid artery stenosis and its predictive significance for the occurrence of cerebral ischaemic events [PDF]

Archives of Medical Science, 2020
Introduction Circulating microRNAs (miRNAs) are widely identified as promi­sing and novel biomarkers for the diagnosis of human diseases. This study investigated the clinical value of miR-532-5p for asymptomatic carotid artery stenosis (CAS) patients and
Deyong Du, Jing Liu, Chengcheng Liu, Zefu Li, Yang Gao, Wensheng Zhang, Haitao Zhang   +6 more
doaj   +4 more sources

Overexpression of miR-532-5p restrains oxidative stress response of chondrocytes in nontraumatic osteonecrosis of the femoral head by inhibiting ABL1 [PDF]

Open Medicine
This study is to probe into the meaning of serum miR-532-5p in nontraumatic osteonecrosis of the femoral head (ONFH), and a molecular mechanism of miR-532-5p in the development of nontraumatic ONFH.
Shang Peng, Liu Ying, Ren Jie, Liu Qingqing, Song Haobo, Jia Junqing, Liu Qiang   +6 more
doaj   +4 more sources

Childhood resolution of early abnormal miRNA following neonatal encephalopathy [PDF]

Scientific Reports
Neonatal Encephalopathy (NE) is a clinical syndrome presenting as neurological dysfunction. Persistent dysregulated Inflammation is associated with NE and miRNA biomarkers may correlate with developmental outcomes.
Johana M. Isaza-Correa, Eman Isweisi, Ronan Murphy, Tim Hurley, Matthew McGovern, Moira O’Reilly, Sean Tamgumus, Graham King, Mary O’Dea, Lynne A Kelly, Mandy Daly, Jan Miletin, Claudine Vavasseur, John Kelleher, Eva M. Jimenez-Mateos, Eleanor J. Molloy   +15 more
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Comprehensive analysis of circular RNA expression dynamics and competitive endogenous RNA network mechanisms during postnatal liver development in juvenile goats [PDF]

Animal Bioscience
Objective This study analyzes the dynamic expression profile and functional mechanisms of circular RNA (circRNA) in the liver of young goats during development from birth to the early weaning stage.
Qing Li, Shanfeng Du, Jianmin Wang, Jiaqing Hu, Tianle Chao   +4 more
doaj   +2 more sources

Selection of reference genes for quantitative analysis of microRNA expression in three different types of cancer.

PLoS ONE, 2022
MicroRNAs (miRNAs) are promising biomarkers in cancer research. Quantitative PCR (qPCR), also known as real-time PCR, is the most frequently used technique for measuring miRNA expression levels.
Yuliya A Veryaskina, Sergei E Titov, Mikhail K Ivanov, Pavel S Ruzankin, Anton S Tarasenko, Sergei P Shevchenko, Igor B Kovynev, Evgenij V Stupak, Tatiana I Pospelova, Igor F Zhimulev   +9 more
doaj   +2 more sources

MicroRNA-532-5p is implicated in the regulation of osteoporosis by forkhead box O1 and osteoblast differentiation

BMC Musculoskeletal Disorders, 2020
Background MicroRNAs (miRNAs) are critical regulators in osteogenesis and cartilage formation. This study was designed to investigate whether miR-532-5p plays a role in the regulation of osteoporosis.
Xinyu Guo, Shijun Wei, Feng Xu, Xianhua Cai, Huasong Wang, Ran Ding   +5 more
doaj   +1 more source

Serum Expression Levels of Certain miRNAs in Predicting Diagnosis, Prognosis, and Response to Chemotherapy in Malignant Pleural Mesothelioma

Balkan Medical Journal, 2022
Background: miRNAs are involved in tumor pathogenesis and can therefore be determined in the primary tumor, plasma and serum, and body fluids. As in various cancers, their role in the diagnosis, prognosis, and treatment of patients with malignant pleural
Muzaffer Metintaş, Güntülü Ak, Cansu Özbayer, Filiz Boğar, Selma Metintaş   +4 more
doaj   +1 more source

Effects of miR-532-5p on human brain microvascular endothelial cells damage induced by ox-LDL via down-regulating CLIC4 expression

Pakistan Journal of Pharmaceutical Sciences, 2020
The effect of miR-532-5p on human brain microvascular endothelial cells damage induced by ox-LDL is studied. HBMEC-3 were cultured and treated with ox-LDL for 24 h to establish a model of cell oxidative damage.
Qiping Yao, Bei Zhu
doaj   +1 more source