Overexpression of miR-532-5p restrains oxidative stress response of chondrocytes in nontraumatic osteonecrosis of the femoral head by inhibiting ABL1 [PDF]
Open Medicine (Poland)This study is to probe into the meaning of serum miR-532-5p in nontraumatic osteonecrosis of the femoral head (ONFH), and a molecular mechanism of miR-532-5p in the development of nontraumatic ONFH.
Shang Peng +6 more
exaly +5 more sources
The prognostic miR-532-5p-correlated ceRNA-mediated lipid droplet accumulation drives nodal metastasis of cervical cancer [PDF]
Journal of Advanced Research, 2022 Introduction: The prognosis for cervical cancer (CC) patients with lymph node metastasis (LNM) is extremely poor. Lipid droplets (LDs) have a pivotal role in promoting tumor metastasis.
Chunliang Shang +7 more
doaj +4 more sources
lncRNA ACTA2-AS1 predicts malignancy and poor prognosis of triple-negative breast cancer and regulates tumor progression via modulating miR-532-5p [PDF]
BMC Molecular and Cell Biology, 2022 Background Dysregulation of ACTA2-AS1 and miR-532-5p and their functions in various cancers have been widely reported. Their potential of serving as biomarkers in triple-negative breast cancer (TNBC) remains unknown.
Yi Peng, Xiaoxi Huang, Hongmei Wang
doaj +4 more sources
The diagnostic value of circulating miR-532-5p in patients with asymptomatic carotid artery stenosis and its predictive significance for the occurrence of cerebral ischaemic events [PDF]
Archives of Medical Science, 2020 Introduction Circulating microRNAs (miRNAs) are widely identified as promising and novel biomarkers for the diagnosis of human diseases. This study investigated the clinical value of miR-532-5p for asymptomatic carotid artery stenosis (CAS) patients and
Deyong Du +6 more
doaj +4 more sources
Childhood resolution of early abnormal miRNA following neonatal encephalopathy [PDF]
Scientific ReportsNeonatal Encephalopathy (NE) is a clinical syndrome presenting as neurological dysfunction. Persistent dysregulated Inflammation is associated with NE and miRNA biomarkers may correlate with developmental outcomes.
Johana M. Isaza-Correa +15 more
doaj +2 more sources
Comprehensive analysis of circular RNA expression dynamics and competitive endogenous RNA network mechanisms during postnatal liver development in juvenile goats [PDF]
Animal BioscienceObjective This study analyzes the dynamic expression profile and functional mechanisms of circular RNA (circRNA) in the liver of young goats during development from birth to the early weaning stage.
Qing Li +4 more
doaj +2 more sources
PLoS ONE, 2022 MicroRNAs (miRNAs) are promising biomarkers in cancer research. Quantitative PCR (qPCR), also known as real-time PCR, is the most frequently used technique for measuring miRNA expression levels.
Yuliya A Veryaskina +9 more
doaj +2 more sources
Multiple microRNAs regulate tacrolimus metabolism through CYP3A5 [PDF]
, 2021 The CYP3A5 gene polymorphism accounts for the majority of inter-individual variability in tacmlimus pharmacokinetics. We found that the basal expression of CYP3A5 in donor grafts also played a significant role in tacrolimus metabolism under the same ...
Gu, Xiang-Qian +10 more
core +1 more source
miRNA Signatures in Sera of Patients with Active Pulmonary Tuberculosis. [PDF]
, 2013 Several studies showed that assessing levels of specific circulating microRNAs (miRNAs) is a non-invasive, rapid, and accurate method for diagnosing diseases or detecting alterations in physiological conditions.
Aloi, Francesco +14 more
core +9 more sources
BMC Musculoskeletal Disorders, 2020 Background MicroRNAs (miRNAs) are critical regulators in osteogenesis and cartilage formation. This study was designed to investigate whether miR-532-5p plays a role in the regulation of osteoporosis.
Xinyu Guo +5 more
doaj +1 more source