Results 31 to 40 of about 229,256 (180)

MicroRNA Expression Profiling in Clear Cell Renal Cell Carcinoma: Identification and Functional Validation of Key miRNAs. [PDF]

open access: yesPLoS ONE, 2015
This study aims to profile dysregulated microRNA (miRNA) expression in clear cell renal cell carcinoma (ccRCC) and to identify key regulatory miRNAs in ccRCC.miRNA expression profiles in nine pairs of ccRCC tumor samples at three different stages and the
Haowei He   +11 more
doaj   +1 more source

Single-cell RNA sequencing for the identification of early-stage lung cancer biomarkers from circulating blood

open access: yesnpj Genomic Medicine, 2021
Lung cancer accounts for more than half of the new cancers diagnosed world-wide with poor survival rates. Despite the development of chemical, radiological, and immunotherapies, many patients do not benefit from these therapies, as recurrence is common ...
Jinhong Kim   +2 more
doaj   +1 more source

Computational and Investigation of miRNA-Gene Regulations in Retinoblastoma Pathogenesis: miRNA Mimics Strategy

open access: yesBioinformatics and Biology Insights, 2015
Purpose Retinoblastoma (RB), a primary pediatric intraocular tumor, arises from primitive retinal layers. Several novel molecular strategies are being developed for the clinical management of RB.
Nalini Venkatesan   +3 more
doaj   +1 more source

MiR-21-5p, miR-18a-5p, miR-27a-3p and miR-423-5p expression in AMI_T0 and CAD groups (n = 3). [PDF]

open access: yes, 2019
(A) MiR-21-5p expression in CAD and AMI_T0 groups. Mann-Whitney U = 196, n.s. (B) MiR-18a-5p expression in CAD and AMI_T0 groups. Mann-Whitney U = 190, n.s. (C) MiR-27a-3p expression in CAD and AMI_T0 groups. Mann-Whitney U = 106, n.s.
Ruggiero Mango (266696)   +11 more
core   +1 more source

BCL11A expression was negatively regulated by hsa-miR-190b-5p. [PDF]

open access: yes, 2023
(A, B) qRT-PCR and Western blot analysis of the mRNA and protein expression levels of BCL11A in 293T cells after transfected hsa-miR-190b-5p mimics and negative control mimics. β-actin gene was used as the internal control. (C) hsa-miR-190b-5p expression
Hailong Huang (1449589)   +9 more
core   +1 more source

Data_Sheet_1_CAGE-miR-140-5p-Wnt1 Axis Regulates Autophagic Flux, Tumorigenic Potential of Mouse Colon Cancer Cells and Cellular Interactions Mediated by Exosomes.pdf [PDF]

open access: yes, 2019
Although the cancer/testis antigen CAGE has been implicated in tumorigenesis, the molecular mechanisms of CAGE-promoted tumorigenesis remain largely unknown.
Seungheon Lee (7862393)   +5 more
core   +1 more source

MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features

open access: yesWorld Journal of Surgical Oncology, 2012
Background MicroRNA (miRNA) expression is known to be deregulated in ovarian carcinomas. However, limited data is available about the miRNA expression pattern for the benign or borderline ovarian tumors as well as differential miRNA expression pattern ...
Lee Heejeong   +8 more
doaj   +1 more source

Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study. [PDF]

open access: yesPLoS ONE, 2015
OBJECTIVE:Plasma miRNAs represent potential minimally invasive biomarkers to monitor and predict outcomes from chemotherapy. The primary goal of the current study-consisting of patients with recurrent, platinum-resistant ovarian cancer-was to identify ...
Eric A Benson   +4 more
doaj   +1 more source

RETRACTED ARTICLE: LINC01410-miR-532-NCF2-NF-kB feedback loop promotes gastric cancer angiogenesis and metastasis [PDF]

open access: yes, 2018
Dysregulation of non-coding RNAs, including miRNAs and lncRNAs has been reported to play vital roles in gastric cancer (GC) carcinogenesis, but the mechanism involved is largely unknown.
Chen-Yuan Wang   +14 more
core   +1 more source

miR-30b-5p inhibits osteoblast differentiation through targeting BCL6 [PDF]

open access: yes, 2022
Human bone marrow mesenchymal stem cells (hBMSCs) are attractive candidates for new therapies to improve bone regeneration and repair. This study was to identify the function of the miR-30b-5p/BCL6 axis in osteogenic differentiation of hBMSCs.
Bin Ye (686390)   +4 more
core   +1 more source

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