Results 31 to 40 of about 4,435 (163)
Scientific Reports, 2022 Fragile X syndrome (FXS) is caused by a mutation in the FMR1 gene which can lead to a loss or shortage of the FMR1 protein. This protein interacts with specific miRNAs and can cause a range of neurological disorders.
Maryam Sotoudeh Anvari +9 more
doaj +1 more source
Expression of nonmuscle myosin IIC is regulated by non-canonical binding activity of miRNAs
iScience, 2023 Summary: The expression of mechanoresponsive nonmuscle myosin II (NMII)C is found to be inducible during tumor progression, but its mechanism is yet to be explored.
Kumarjeet Banerjee +6 more
doaj +1 more source
Blood miRNAs Are Linked to Frequent Asthma Exacerbations in Childhood Asthma and Adult COPD
Non-Coding RNA, 2022 MicroRNAs have been independently associated with asthma and COPD; however, it is unclear if microRNA associations will overlap when evaluating retrospective acute exacerbations.
Anshul Tiwari +9 more
doaj +1 more source
European review for medical and pharmacological sciences, 2018 Dysregulated miR-532-5p has been observed in epithelial ovarian cancer (EOC). However, the potential biological function and clinical significance have not been fully explained. The study aimed to investigate the prognostic value and potential role of miR-532-5p in EOC.MiR-532-5p and Twist homolog 1 (TWIST1) mRNA expression were examined using ...
Wei, H. +4 more
openaire +2 more sources
Frontiers in Endocrinology, 2018 The reduced expression of solute carrier family 2, facilitated glucose transporter member 4 (GLUT4) and hexokinase-2 (HK2) in skeletal muscle participates in insulin resistance of diabetes mellitus (DM).
João V. Esteves +5 more
doaj +1 more source
MicroRNA Expression Profiling in Clear Cell Renal Cell Carcinoma: Identification and Functional Validation of Key miRNAs. [PDF]
PLoS ONE, 2015 This study aims to profile dysregulated microRNA (miRNA) expression in clear cell renal cell carcinoma (ccRCC) and to identify key regulatory miRNAs in ccRCC.miRNA expression profiles in nine pairs of ccRCC tumor samples at three different stages and the
Haowei He +11 more
doaj +1 more source
npj Genomic Medicine, 2021 Lung cancer accounts for more than half of the new cancers diagnosed world-wide with poor survival rates. Despite the development of chemical, radiological, and immunotherapies, many patients do not benefit from these therapies, as recurrence is common ...
Jinhong Kim +2 more
doaj +1 more source
Bioinformatics and Biology Insights, 2015 Purpose Retinoblastoma (RB), a primary pediatric intraocular tumor, arises from primitive retinal layers. Several novel molecular strategies are being developed for the clinical management of RB.
Nalini Venkatesan +3 more
doaj +1 more source
MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features
World Journal of Surgical Oncology, 2012 Background MicroRNA (miRNA) expression is known to be deregulated in ovarian carcinomas. However, limited data is available about the miRNA expression pattern for the benign or borderline ovarian tumors as well as differential miRNA expression pattern ...
Lee Heejeong +8 more
doaj +1 more source
Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study. [PDF]
PLoS ONE, 2015 OBJECTIVE:Plasma miRNAs represent potential minimally invasive biomarkers to monitor and predict outcomes from chemotherapy. The primary goal of the current study-consisting of patients with recurrent, platinum-resistant ovarian cancer-was to identify ...
Eric A Benson +4 more
doaj +1 more source