Results 51 to 60 of about 229,256 (180)

Placental microRNA expression associates with birthweight through control of adipokines: results from two independent cohorts

open access: yesEpigenetics, 2021
MicroRNAs are non-coding RNAs that regulate gene expression post-transcriptionally. In the placenta, the master regulator of foetal growth and development, microRNAs shape the basic processes of trophoblast biology and specific microRNA have been ...
Elizabeth M. Kennedy   +10 more
doaj   +1 more source

Alterations in MicroRNA and Cytokine Expressions in Placental and Amniotic Tissues of COVID‐19 Affected Pregnant Women

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Since 2019, coronavirus disease 2019 (COVID‐19) has been associated with increased risks of preterm birth and placental complications. We prospectively investigated alterations in microRNAs (miRNAs) and cytokines in placental and amniotic tissues from pregnant women with and without COVID‐19 to evaluate the infection's impact on pregnancy ...
Wei‐Chun Chen   +3 more
wiley   +1 more source

MiR-497-5p, miR-195-5p and miR-455-3p function as tumor suppressors by targeting hTERT in melanoma A375 cells [PDF]

open access: yes, 2018
Li Chai,1 Xiao-Jing Kang,2 Zhen-Zhu Sun,3 Ming-Feng Zeng,2 Shi-Rong Yu,2 Yuan Ding,2 Jun-Qin Liang,2 Ting-Ting Li,2 Juan Zhao2 1Xinjiang Medical University, Urumqi, China; 2Department of Dermatology and Venereology, People’s Hospital of Xinjiang ...
Sun ZZ   +8 more
core  

Association of recurrent venous thromboembolism and circulating microRNAs

open access: yesClinical Epigenetics, 2019
Background Patients with unprovoked first venous thromboembolism (VTE) are at a high risk of recurrence. Although circulating microRNAs (miRNAs) have been found to be associated with VTE and are markers of hypercoagulability, this study is the first to ...
Xiao Wang   +7 more
doaj   +1 more source

Synthesis, Characterization, and Optical Properties of Undoped and Te‐Doped W(SxSe(1−x))2 and Core‐Shell WS2@W(SxSe(1−x))2 Nanotubes

open access: yesIsrael Journal of Chemistry, Volume 66, Issue 4, July 2026.
W(SxSe1−x)2, Te:WSSe, and WS2@WSSe nanotubes were synthesized through controlled precursor composition. The W(SxSe1−x)2 and Te:WSSe nanotubes exhibit small‐diameter (<30 nm), high‐yield, and well‐defined excitonic transitions. Composition tuning via S/Se ratios increases interlayer spacing with higher Se content. The incorporation of Te remains limited
Philip Nathaniel Immanuel   +11 more
wiley   +1 more source

The miR-590 C57T SNP reduces levels of miR-590-5p and miR-590-3p, without affecting the levels of pri-miR-590 and pre-miR-590. [PDF]

open access: yes, 2016
(A) Quantification of pri-miR-590 by qRT-PCR normalized by GAPDH. Mean ± SD (n = 3). HEK293T cells were transfected with the pri-miR-590-WT or pri-miR-590-SNP plasmids. The empty plasmid was used as negative control.
Suresh K. Kandasamy (2794198)   +15 more
core   +1 more source

Screening and molecular mechanism research on bile microRNAs associated with chemotherapy efficacy in perihilar cholangiocarcinoma

open access: yesiScience
Summary: The efficacy of hepatic arterial infusion chemotherapy (HAIC) with oxaliplatin (OXA) and 5-fluorouracil (5-Fu) for treating advanced perihilar cholangiocarcinoma (pCCA) has been demonstrated, yet the survival benefits of HAIC for pCCA patients ...
Shijie Fu   +9 more
doaj   +1 more source

Dysregulation of MicroRNAs and Target Genes Networks in Peripheral Blood of Patients With Sporadic Amyotrophic Lateral Sclerosis

open access: yesFrontiers in Molecular Neuroscience, 2018
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease. While genetics and other factors contribute to ALS pathogenesis, critical knowledge is still missing and validated biomarkers for monitoring the disease activity ...
Maria Liguori   +8 more
doaj   +1 more source

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

open access: yesJournal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu   +3 more
wiley   +1 more source

Osteoarthritis: Epidemiology, Diagnosis, and Treatment

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru   +7 more
wiley   +1 more source

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