Results 51 to 60 of about 5,056 (201)

Computational and Investigation of miRNA-Gene Regulations in Retinoblastoma Pathogenesis: miRNA Mimics Strategy

Bioinformatics and Biology Insights, 2015
Purpose Retinoblastoma (RB), a primary pediatric intraocular tumor, arises from primitive retinal layers. Several novel molecular strategies are being developed for the clinical management of RB.
Nalini Venkatesan, Perinkulam Ravi Deepa, Vikas Khetan, Subramanian Krishnakumar   +3 more
doaj   +1 more source

Genome-wide mRNA and miRNA expression profiling reveal multiple regulatory networks in colorectal cancer [PDF]

, 2015
Despite recent advances in cancer management, colorectal cancer (CRC) remains the third most common cancer and a major health-care problem worldwide. MicroRNAs have recently emerged as key regulators of cancer development and progression by targeting ...
Abdulla, MH, Al-Obeed, O, Alajez, Nehad, Aldahmash, Abdallah, Hamam, R, Kassem, Moustapha, Mohammed, MA, Vishnubalaji, R   +7 more
core   +2 more sources

Mitochondrial epigenetics in aging and cardiovascular diseases [PDF]

, 2023
Mitochondria are cellular organelles which generate adenosine triphosphate (ATP) molecules for the maintenance of cellular energy through the oxidative phosphorylation. They also regulate a variety of cellular processes including apoptosis and metabolism.
Costantino, Sarah, Geiger, Martin, Gorica, Era, Mengozzi, Alessandro, Mohammed, Shafeeq Ahmed, Mongelli, Alessia, Paneni, Francesco, Ruschitzka, Frank   +7 more
core   +1 more source

MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features

World Journal of Surgical Oncology, 2012
Background MicroRNA (miRNA) expression is known to be deregulated in ovarian carcinomas. However, limited data is available about the miRNA expression pattern for the benign or borderline ovarian tumors as well as differential miRNA expression pattern ...
Lee Heejeong, Park Chul, Deftereos Georgios, Morihara Janice, Stern Joshua E, Hawes Stephen E, Swisher Elizabeth, Kiviat Nancy B, Feng Qinghua   +8 more
doaj   +1 more source

Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study. [PDF]

PLoS ONE, 2015
OBJECTIVE:Plasma miRNAs represent potential minimally invasive biomarkers to monitor and predict outcomes from chemotherapy. The primary goal of the current study-consisting of patients with recurrent, platinum-resistant ovarian cancer-was to identify ...
Eric A Benson, Todd C Skaar, Yunlong Liu, Kenneth P Nephew, Daniela Matei   +4 more
doaj   +1 more source

Systematic Assessment of Blood-Borne MicroRNAs Highlights Molecular Profiles of Endurance Sport and Carbohydrate Uptake [PDF]

, 2019
Multiple studies endorsed the positive effect of regular exercise on mental and physical health. However, the molecular mechanisms underlying training-induced fitness in combination with personal life-style remain largely unexplored.
Backes, Christina, Fehlmann, Tobias, Hecksteden, Anne, Keller, Andreas, Kern, Fabian, Ludwig, Nicole, Maldener, Esther, Meese, Eckart, Meyer, Tim, Suleymanov, Artur   +9 more
core   +1 more source

Identification of miRNAs in extracellular vesicles as potential diagnostic markers for pediatric epilepsy and drug-resistant epilepsy via bioinformatics analysis

Frontiers in Pediatrics, 2023
BackgroundPediatric epilepsy (PE) is a common neurological disease. However, many challenges regarding the clinical diagnosis and treatment of PE and drug-resistant epilepsy (DRE) remain unsettled.
Yucai Ruan, Xuhui Deng, Jun Liu, Xiaobing Xiao, Zhi Yang, Zhi Yang   +5 more
doaj   +1 more source

MiRNA-532-5p Regulates CUMS-Induced Depression-Like Behaviors and Modulates LPS-Induced Proinflammatory Cytokine Signaling by Targeting STAT3

Neuropsychiatric Disease and Treatment, 2020
Xue Yan,* Dehao Zeng,* He Zhu, Yijing Zhang, Yuying Shi, Yingxiu Wu, Hongmei Tang, Detang Li Pharmaceutical Department, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510405, People’s ...
Yan X, Zeng D, Zhu H, Zhang Y, Shi Y, Wu Y, Tang H, Li D   +7 more
doaj  

Roles of microRNA on cancer cell metabolism [PDF]

, 2012
Advanced studies of microRNAs (miRNAs) have revealed their manifold biological functions, including control of cell proliferation, cell cycle and cell death.
Bing Chen, Hongbin Li, Pengbo Yang, Shufang Liang, Xia Zhao, Xiao Zeng, Xinyu Liu   +6 more
core   +1 more source

CircANTXR1 Contributes to the Malignant Progression of Hepatocellular Carcinoma by Promoting Proliferation and Metastasis

Journal of Hepatocellular Carcinoma, 2021
Changshan Huang, Wei Yu, Qian Wang, Tao Huang, Yuechao Ding Department of Hepato-Biliary-Pancreatic Surgery, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, 450003, Henan, People’s Republic of ChinaCorrespondence: Changshan ...
Huang C, Yu W, Wang Q, Huang T, Ding Y
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