Results 21 to 30 of about 229,256 (180)
miR-532/miR-3064 overexpression inhibits, whereas miR-532/miR-3064 silencing promotes proliferation and invasion in OC cells. [PDF]
, 2017 (A, B) Cell morphology of OC cells transfected with either miR-532/miR-3064 mimics (A) or miR-532/miR-3064 inhibitors (B); (C, D) Representative images of invaded ES-2 (C) and SKOV-3 (D) cells transfected as indicated; (E, F) Cell counting kit-8 assay (E)
Ai-Hua Wang (3836656) +4 more
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Scientific Reports, 2022 Fragile X syndrome (FXS) is caused by a mutation in the FMR1 gene which can lead to a loss or shortage of the FMR1 protein. This protein interacts with specific miRNAs and can cause a range of neurological disorders.
Maryam Sotoudeh Anvari +9 more
doaj +1 more source
miR-149-5p mitigates tumor necrosis factor-α-induced chondrocyte apoptosis by inhibiting TRADD [PDF]
, 2020 Introduction Chondrocyte apoptosis as a prominent characteristic is usually accompanied by cartilage degeneration in osteoarthritis (OA). Herein, we aimed to determine the roles of miR-149-5p in tumor necrosis factor-α (TNF-α)-induced chondrocyte ...
Shi-cheng Xie +4 more
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Expression of nonmuscle myosin IIC is regulated by non-canonical binding activity of miRNAs
iScience, 2023 Summary: The expression of mechanoresponsive nonmuscle myosin II (NMII)C is found to be inducible during tumor progression, but its mechanism is yet to be explored.
Kumarjeet Banerjee +6 more
doaj +1 more source
Bioinformatics predicted oar-miR-3955-5p binding sites on XLOC005698, and oar-miR-544-5p binding sites on XLOC000629. [PDF]
, 2016 (a) Alignment between XLOC005698 and oar-miR-3955-5p as well as between XLOC000629 and oar-miR-544-5p. (b) The oar-miR-3955-5p miRNA binding sites on XLOC005698. (c)The oar-miR-544-5p miRNA binding sites on XLOC000629.
Tingting Guo (101831) +8 more
core +1 more source
miR-34a-5p affects the EZH2 protein pathway. [PDF]
, 2023 (A) Binding sites of EZH2 and miR-34a-5p were predicted through bioinformatics analysis. (BⅠ-Ⅱ) Double luciferase reporter experiment confirmed this prediction.
Chengcheng Liao (12402943) +16 more
core +1 more source
Blood miRNAs Are Linked to Frequent Asthma Exacerbations in Childhood Asthma and Adult COPD
Non-Coding RNA, 2022 MicroRNAs have been independently associated with asthma and COPD; however, it is unclear if microRNA associations will overlap when evaluating retrospective acute exacerbations.
Anshul Tiwari +9 more
doaj +1 more source
Frontiers in Endocrinology, 2018 The reduced expression of solute carrier family 2, facilitated glucose transporter member 4 (GLUT4) and hexokinase-2 (HK2) in skeletal muscle participates in insulin resistance of diabetes mellitus (DM).
João V. Esteves +5 more
doaj +1 more source
miR-218-5p directly targets HMGB2 and CMPK1 3'UTR. [PDF]
, 2019 (A). Luciferase activity in HEK293T cells cotransfected with miR-218-5p mimic (miR-218-5p; 10 nM) or its control (NC of mimic; 10 nM) and the reporter constructs for 48 h. (B). Luciferase activity in HEK293T cells cotransfected with increasing amounts of
Qin Yan (281622) +6 more
core +1 more source
TGIF2 expression in miR-210-5p-overexpressing cells. [PDF]
, 2021 (A) Predicted miR-210-5p binding sites in the TGIF2-3`UTR. (B) HOS cells were transfected with the luciferase reporter vector of TGIF2-3`UTR (upper image) and various amounts of miR-210-5p mimic, and dual-luciferase activity was measured 30 h later. (C-D)
Lixia Huang (429197) +9 more
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