Results 91 to 100 of about 1,582,384 (285)
VirusesTenofovir (TFV) is the active form of the prodrugs tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF), both clinically prescribed as HIV reverse transcriptase inhibitors.
Andreia Costa-Tuna +5 more
doaj +1 more source
The applicability of performance-based funding mechanisms in Malaysian Public Universities [PDF]
, 2019 A performance-based funding (PBF) mechanism is now widespread in educational institutions in both developed and developing countries. The Malaysian Government also has intention to implement PBF in public universities, yet no study has explored the ...
Kek, Siok Yee
core
Advanced Photonics Research, Volume 6, Issue 5, May 2025.Microfabrication using nano‐ to micron‐sized blocks has transformative potential for next‐gen electronics, optoelectronics, and materials. Traditional methods are limited by scalability and precision. STIC, a single‐laser system for precise colloid manipulation and immobilization using femtosecond lasers, is introduced that enables efficient 3D ...
Krishangi Krishna +4 more
wiley +1 more source
Advanced Robotics Research, EarlyView.An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy +13 more
wiley +1 more source
Development and evaluation of TUMS medium, a novel biphasic culture medium for isolation of Brucella spp. from patients [PDF]
Background and objectives: There are limitations in time and technique for isolation of Brucella from patients. We developed a new Brucella culture medium and evaluated its efficiency compared to BACTEC blood culture system and serology.
حجازی, محمد جواد +3 more
core
Advanced Science, EarlyView.A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li +7 more
wiley +1 more source
¿Cumple la privatización lo que promete? El acceso a los servicios telefónicos y el ingreso familiar en zonas rurales pobres empleando un experimento cuasinatural en Perú [PDF]
(Disponible en idioma inglés únicamente) Este trabajo aprovecha un experimento cuasinatural realizado en Perú, en el que el gobierno ordenó a la compañía de telecomunicaciones privatizada que instalara aleatoriamente y operara teléfonos públicos en ...
Alberto Chong +2 more
core
Advanced Science, EarlyView.Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao +4 more
wiley +1 more source
Advanced Science, EarlyView.Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider +20 more
wiley +1 more source
A potent Lassa virus antiviral targets an arenavirus virulence determinant.
PLoS Pathogens, 2018 Arenaviruses are a significant cause of hemorrhagic fever, an often-fatal disease for which there is no approved antiviral therapy. Lassa fever in particular generates high morbidity and mortality in West Africa, where the disease is endemic, and a ...
Ikenna G Madu +13 more
doaj +1 more source