Results 141 to 150 of about 1,527,120 (330)

KMT2C Loss Promotes NF2‐Wildtype Meningioma Progression and Ferroptosis Sensitivity via Epigenetic Repression of Hippo Signaling

Advanced Science, EarlyView.
In NF2–wild‐type meningiomas, loss of the epigenetic regulator KMT2C suppresses NF2 transcription and inactivates Hippo signaling, driving tumor progression and increasing ferroptosis sensitivity. Restoration of histone acetylation reverses these effects and inhibits tumor growth, identifying KMT2C as a key regulator linking epigenetic control, NF2 ...
Liuchao Zhang, Yangfan Ye, Wei Gu, Xinyue Wang, Nuo Chen, Qixin He, Lei Xu, Pengzhan Zhao, Guoqiang Fu, Guangyao Yuan, Wenqian Shi, Honglu Chao, Yiming Tu, Jing Ji   +13 more
wiley   +1 more source

Scalable Upcycling of Spent Lithium‐Ion Battery Anodic Graphite to Electronic‐Grade Graphene

Advanced Science, EarlyView.
Graphite anodes from spent lithium‐ion batteries are upcycled into electronic‐grade graphene nanoplatelets for highly conductive screen printing inks (> 104 S m−1). Screen‐printed micro‐supercapacitors confirm the utility of the upcycled graphene (1.78 mF/cm2 capacitance for > 10 000 cycles). Life cycle assessment and techno‐economic analysis highlight
Janan Hui, Jenna N. Trost, Wesley Y. Chen, Maryam Khalaj, Lindsay E. Chaney, Peyton Melin, Albert L. Lipson, Jennifer B. Dunn, Mark C. Hersam   +8 more
wiley   +1 more source

Erratum to “Twice- or once-daily dosing of direct oral anticoagulants and gastrointestinal bleeding in patient with atrial fibrillation” [Am. Heart J. Plus: Cardiol. Res. Pract. Volume 22, October 2022, 100203]

American Heart Journal Plus, 2023
Tadakiyo Ido, Shun Sasaki, Yohei Sotomi, Akio Hirata, Nobuhiko Makino, Takaharu Hayashi, Yasushi Sakata, Atsushi Hirayama, Yoshiharu Higuchi   +8 more
doaj   +1 more source

Annual Report of the 2022 National Clinical Database: Decade‐Long Trends and Current Status of Gastroenterological Surgery in Japan

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The National Clinical Database (NCD) of Japan is the largest nationwide registry, covering over 95% of surgeries in the country. This 2022 annual report summarizes the short‐term outcomes of gastroenterological surgeries and discusses trends and insights over the past decade.
Koshi Kumagai, Arata Takahashi, Hideki Ueno, Naoki Hiki, Yoshiki Kajiwara, Tomoki Ebata, Takao Otsuka, Taro Oshikiri, Yoshihiro Kakeji, Takanori Goi, Akio Saiura, Hiroshi Saeki, Chie Tanaka, Masanori Tokunaga, Tsutomu Fujii, Satoru Matsuda, Tsunekazu Mizushima, Hiroyuki Yamamoto, Yuko Kitagawa, Ken Shirabe   +19 more
wiley   +1 more source

Predictive, Data‐Driven Design of Red‐Light Photoredox Catalysts for C─Heteroatom Bond Formation

Angewandte Chemie, EarlyView.
From redox numbers to red light: Donor oxidation and core reduction potentials predict E0‐0 in cyanoarene dyes, guiding selection of an efficient red‐light catalyst, 4MeODPATPN (PC13). Under 620 nm light, PC13 facilitates Ni‐catalyzed C─heteroatom cross‐couplings (C─N, C─O, C─S) with high functional‐group tolerance and reduced hydrodehalogenation ...
Amir Gizatullin, Tingting Yuan, Sascha Grotjahn, Luigi Cavallo, Burkhard König, Chen Zhu, Magnus Rueping   +6 more
wiley   +2 more sources

LncRNA SNHG6 promotes breast cancer progression and epithelial-mesenchymal transition via miR-543/LAMC1 axis

Breast Cancer Research and Treatment, 2021
You-Quan Wang, Guo Huang, Juan Chen, H. Cao, Wensheng Xu   +4 more
semanticscholar   +1 more source

Prognostic Significance of Portal Vein Tumor Thrombus in Pancreatic Ductal Adenocarcinoma Treated With Chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To examine the significance of portal vein tumor thrombus (PVTT) as a prognostic factor for patients with pancreatic ductal adenocarcinoma (PDAC) treated with chemoradiotherapy (CRT) followed by surgery. Methods The study retrospectively examined 313 patients with borderline resectable (BR) or locally advanced (LA) PDAC who underwent CRT ...
Aoi Hayasaki, Motonori Nagata, Miki Usui, Hiroshi Imai, Yusuke Iizawa, Akihiro Tanemura, Yasuhiro Murata, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno   +9 more
wiley   +1 more source

Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis

Journal of Translational Medicine
Background Hepatocellular carcinoma (HCC) remains a leading life-threatening health challenge worldwide, with pressing needs for novel therapeutic strategies. Sphingosine kinase 1 (SphK1), a well-established pro-cancer enzyme, is aberrantly overexpressed
Xin Tracy Liu, Yu Huang, Da Liu, Yingxin Celia Jiang, Min Zhao, Long Hoa Chung, Xingxing Daisy Han, Yinan Zhao, Jinbiao Chen, Paul Coleman, Ka Ka Ting, Collin Tran, Yingying Su, Claude Vincent Dennis, Atul Bhatnagar, Ken Liu, Anthony Simon Don, Mathew Alexander Vadas, Mark Douglas Gorrell, Shubiao Zhang, Michael Murray, Mary Meltem Kavurma, Geoffrey William McCaughan, Jennifer Ruth Gamble, Yanfei Qi   +24 more
doaj   +1 more source

Novel Criteria to Provide a Locality/Normality Degree in Molecules and Their Relevance in Physical Chemistry

Molecules
In contrast to the traditional analysis of molecules using local mode behavior, where the degree of locality is given through a function in terms of Morse potential parameters, new criteria for locality/normality (LN) suitable for application to any ...
Eduardo Suárez, Oscar Guzmán-Juárez, Renato Lemus   +2 more
doaj   +1 more source

ObliviSync: Practical Oblivious File Backup and Synchronization [PDF]

, 2016
Oblivious RAM (ORAM) protocols are powerful techniques that hide a client's data as well as access patterns from untrusted service providers. We present an oblivious cloud storage system, ObliviSync, that specifically targets one of the most widely-used ...
Aviv, Adam J., Choi, Seung Geol, Mayberry, Travis, Roche, Daniel S.   +3 more
core   +1 more source