Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Health-related quality of life and lifetime QALY loss among Indigenous Australians with chronic conditions: an age-stratified analysis. [PDF]
Haque R +7 more
europepmc +1 more source
12 Es war III (Konrad Stekl) [02:53] (KUG KD 55)
Text: Bruno Ertler Komposition: Konrad Stekl Interpret*innen: Birgit Stöckler (Sopran), Maria Lerchenberger (Tenor), Petar Karagenov (Klavier), Christoph Hammer (Geige), Tom Sol (Sprecher), Harald Haslmayr (Moderator) Album: Bruno Ertler "Ewigkeiten" und
core
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Dyadic adjustment for younger individuals following stroke: A cross-sectional study. [PDF]
Kwamanakweenda J +2 more
europepmc +1 more source
Værktøjer til udvikling af 55+ politik samt afholdelse af 55+ samtaler på arbejdspladsen bestående af dialogkort, ledervejledning og medarbejdervejledning. Forskning viser, at samtaler om seniorarbejdslivet skaber længere arbejdsliv.
Wulff, Anna Lyngdal +3 more
core
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Correction: Determining farm surface porcine reproductive and respiratory syndrome virus (PRRSV) contamination through viability RT-qPCR. [PDF]
Melini CM +3 more
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Relationship between histopathological findings and RAI in non-papillary follicular cell-derived thyroid carcinoma. [PDF]
Yamazaki H +7 more
europepmc +1 more source

