Results 31 to 40 of about 4,877,711 (265)
A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho +7 more
wiley +1 more source
Molbank, 2006 Synthesis of 5,5’-biindole was carried out by the Madelung indole reaction. Under strong basic conditions and high temperatures (350 ºC), N,N’-bis-formyl-o-tolidine underwent cyclization to produce high amounts of the dimeric indole. Full and unambiguous
Reyes Tamez-Guerra +6 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
5,5′-Thiobis(3-methoxy-4H-1,2,6-thiadiazin-4-one)
Molbank, 2019 The reaction of 3-chloro-5-methoxy-4H-1,2,6-thiadiazin-4-one (9) with Na2S·9H2O (0.5 equiv) in tetrahydrofuran (THF) at ca. 20 °C for 20 h gives 5,5′-thiobis(3-methoxy-4H-1,2,6-thiadiazin-4-one) (10) in a 44% yield as yellow needles.
Andreas S. Kalogirou +1 more
doaj +1 more source
LIPIcs, Volume 55, ICALP'16, Complete Volume [PDF]
, 2016 LIPIcs, Volume 55, ICALP'16, Complete ...
Mitzenmacher, Michael +3 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
1,1′-Dibromo-2,2′,5,5′-tetrakis(methylthio)ferrocene
Molbank, 2023 The reaction of 1,1′-dibromoferrocene with three equivalents of LiTMP and Me2S2 produces a product mixture, from which 1,1′-dibromo-2,2′-bis(methylthio)ferrocene (4) can be isolated in moderate yield. Further treatment of the isolated compound 4 with two
Tobias Blockhaus +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2018 The title compounds 5,5′-(propane-2,2-diyl)bis(2-hydroxybenzaldehyde), C17H16O4, (1), and 5,5′-(propane-2,2-diyl)bis(2-hydroxyisophthalaldehyde), C19H16O6, (2), crystallize with one molecule in the asymmetric unit.
Rosario C. Sausa +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source