Results 71 to 80 of about 17,001,478 (281)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Language switching in a digital library; does it make a difference if the default language is set to Maori? [PDF]
In this paper we investigate the effect of default interface language on usage patterns of the Niupepa digital library (a collection of historic Māori language newspapers), by switching the default interface language between Māori and English in ...
Cunningham, Sally Jo +2 more
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Volume 55, Number 2 - February 1976 [PDF]
Volume 55, Number 2 - February 1976. 19 pages including covers and advertisements. Contributions Perel, Jane Lunin the car wash Maciag, Drew Pillow Mountain Stachura, Betsy Sunset Trilogy Charbineau, Jay The Fat Girl Shea, Nancy Untitled ...
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
5,5’-Selenobis(1-benzyl-2-oxo-1,2-dihydropyridine-4-carbaldehyde)
Selenium compounds have garnered significant attention in the field of medicinal chemistry due to their unique biochemical properties and potential therapeutic applications for different pathologies.
Emeline Grosjean +5 more
doaj +1 more source
Volume 55, Number 1 - November 1975 [PDF]
Volume 55, Number 1 - November 1975. 27 pages including covers and advertisements. Contributions Slonina, Patricia L. Taking Out the Boat Prevey, Debra impressions: fall Tremblay, Bill Janis Joplin & The Invention of Barbed Wire Schaffer, Dora ...
core +1 more source
Dust in the 55 Cancri planetary system
The presence of debris disks around $\sim$ 1-Gyr-old main sequence stars suggests that an appreciable amount of dust may persist even in mature planetary systems.
Dominik C. +10 more
core +2 more sources
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source

