Results 71 to 80 of about 56,719,399 (260)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

El Diálogo 5+5 y la iniciativa 5+5 defensa

open access: yesRevista UNISCI, 2015
El Diálogo 5+5 es el foro activo de diálogo y cooperación más antiguo que existe entre los países europeos del Mediterráneo Occidental y los países del Magreb.
Javier Ignacio García
doaj  

Genetic characteristics of the isolate of human adenovirus type 55 (Adenoviridae: Mastadenovirus) isolated in Moscow in 2022

open access: yesВопросы вирусологии
Introduction. Adenovirus infection occurs globally in the form of sporadic cases and isolated outbreaks. Human adenovirus type 55 (HAdV-55), endemic in China and South Korea, causes acute respiratory viral infections (ARVI) of varying severity, both ...
Daniil A. Shein   +11 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Magnetar crust electron capture for $$^{55}$$ 55 Co and $$^{56}$$ 56 Ni

open access: yesEuropean Physical Journal C: Particles and Fields, 2018
Based on the relativistic mean-field effective interaction principle and random phase approximation theory in superstrong magnetic fields (SMFs), we present an analysis of the influence of SMFs on the electron Fermi energy, nuclear blinding energy ...
Jing-Jing Liu, Dong-Mei Liu
doaj   +1 more source

Boletim Diocesano, Edição 55/56.

open access: yes, 1973
Boletim publicado mensalmente pela Cúria Diocesana de Nova Iguaçu, entre 1969 e 1992, contendo documentos variados, entre os quais cartas circulares do Bispo, aras de reuniões das organizações pastorais, além de informações gerais, como o calendário de ...
Hypólito, Dom Adriano Mandarino
core  

PowerTAC 2015-04 Qualifying 51-55

open access: yes, 2015
<p>Log and boot files of games 51 - 55</p ...
PowerTAC, PowerTAC (5191558)
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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