Results 81 to 90 of about 17,983,967 (290)

Language switching in a digital library; does it make a difference if the default language is set to Maori? [PDF]

open access: yes, 2004
In this paper we investigate the effect of default interface language on usage patterns of the Niupepa digital library (a collection of historic Māori language newspapers), by switching the default interface language between Māori and English in ...
Cunningham, Sally Jo   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Penetrating knife in the maxillary sinus: Report of a rare case. [PDF]

open access: yes, 2012
Presence of foreign bodies in the paranasal sinuses are not common findings.Many cases have been reported so far with foreign bodies like dental amalgam, chopsticks, gutta percha pellets, tooth, glue and even bullets.
Ethirajan, Sivakumar   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

5,5’-Selenobis(1-benzyl-2-oxo-1,2-dihydropyridine-4-carbaldehyde)

open access: yesMolbank
Selenium compounds have garnered significant attention in the field of medicinal chemistry due to their unique biochemical properties and potential therapeutic applications for different pathologies.
Emeline Grosjean   +5 more
doaj   +1 more source

Onoma 55. (2020)

open access: yesNévtani Értesítő, 2022
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Dávid Wendl
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

BEST AGERS ACTIVATION TOOLBOX – RESULTS OF THE RESEARCH

open access: yesResearch on Enterprise in Modern Economy Theory and Practice, 2012
In recent years, the fact to make more use of the knowledge and expertise of people aged 55+ years – called “Best Agers” – has been increasingly recognized. The usage of these skills is becoming more and more important. Due to this finding, the number
Frank Buettner   +2 more
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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