Results 21 to 30 of about 371,740 (247)

2-(3,4-Dimethoxyphenyl)-4-(thiophen-2-yl)-2,3-dihydro-1,5-benzothiazepine

open access: yesActa Crystallographica Section E, 2014
In the title compound, C21H19NO2S2, the seven-membered thiazepine ring adopts a slightly distorted twist boat conformation. The dihedral angle between the benzene rings is 67.4 (2)°. The mean plane of the thiophene ring is twisted by 59.3 (2) and 87.7 (2)
B. C. Manjunath   +5 more
doaj   +1 more source

Microwave assisted hydrothermal synthesis of Ag2O/α-Bi2O3 heterostructures with highly enhanced photocatalysis and their environmental interest

open access: yesChemical Physics Impact, 2023
A methodological analysis is made in the rational synthesis of the Ag2O/α-Bi2O3, p-n junction heterostructure with significant application, possessing substantial electron-hole recombination acting as solar catalysts through powerful and modest microwave
Srikantaswamy Shivanna   +4 more
doaj   +1 more source

Does Vertebroplasty Affect Radiation Dose Distribution?: Comparison of Spatial Dose Distributions in a Cement-Injected Vertebra as Calculated by Treatment Planning System and Actual Spatial Dose Distribution

open access: yesRadiology Research and Practice, 2012
Purpose. To assess differences in dose distribution of a vertebral body injected with bone cement as calculated by radiation treatment planning system (RTPS) and actual dose distribution. Methods.
Atsushi Komemushi   +10 more
doaj   +1 more source

(E)-1-(Benzo[d][1,3]dioxol-5-yl)-3-(2,3-dichlorophenyl)prop-2-en-1-one

open access: yesIUCrData, 2017
In the title compound, C16H10Cl2O3, the olefinic double bond adopts an E conformation [C—C=C—C torsion angle = −172.9 (3)°]. The dihedral angle between the benzodioxole and dichlorobenzene rings is 5.57 (9)°.
D. M. Lokeshwari   +5 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

2-(2-Isopropylphenoxy)acetic acid

open access: yesIUCrData, 2016
In the title compound, C11H14O3, the pendant –OCH2COOH chain is in an extended conformation and almost lies in the plane of the benzene ring, as indicated by the dihedral angle of 2.61 (5)°.
Yasser Hussein Issa Mohammed   +5 more
doaj   +1 more source

Graphene nano-platelets polyvinyl alcohol nanocomposite electrode for real time ECG signal acquisition

open access: yesBiosensors and Bioelectronics: X, 2022
This paper highlights the development of graphene nanoplatelets polyvinyl alcohol(GNP@PVA) nanocomposite electrode to acquire real time Electrocardiogram(ECG) signal. In order to create GNP@PVA nanocomposite, solution casting was used.
Anitha S. Prasad   +3 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

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