Results 51 to 60 of about 1,476,815 (405)

Spectrophotometric Determination of Mycophenolate Mofetil as Its Charge-Transfer Complexes with Two π-Acceptors

open access: yesJournal of Analytical Methods in Chemistry, 2012
Two simple, selective, and rapid spectrophotometric methods are described for the determination of mycophenolate mofetil (MPM) in pure form and in tablets.
K. B. Vinay   +4 more
doaj   +1 more source

1-(2′-Ethoxy-4′-fluoro-[1,1′-biphenyl]-4-yl)-4-phenyl-1H-1,2,3-triazole

open access: yesIUCrData, 2016
In the title compound, C22H18FN3O, the triazole ring is planar. The plane of the triazole ring makes dihedral angles of 19.31 (10), 20.52 (10) and 39.82 (9)° with the planes of the benzene rings, indicating the overall nonplanarity of the molecule.
Maryam Gilandoust   +4 more
doaj   +1 more source

2-(3,4-Dimethoxyphenyl)-4-(thiophen-2-yl)-2,3-dihydro-1,5-benzothiazepine

open access: yesActa Crystallographica Section E, 2014
In the title compound, C21H19NO2S2, the seven-membered thiazepine ring adopts a slightly distorted twist boat conformation. The dihedral angle between the benzene rings is 67.4 (2)°. The mean plane of the thiophene ring is twisted by 59.3 (2) and 87.7 (2)
B. C. Manjunath   +5 more
doaj   +1 more source

Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1132-1154, April 2025.
PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang   +6 more
wiley   +1 more source

The Experimental Results of the Blocking Oscillator [PDF]

open access: yes, 1982
6KJ00003571718論文Articledepartmental bulletin ...
570, Sato, Takeji
core  

Estrogen-mediated DNMT1 and DNMT3A recruitment by EZH2 silences miR-570-3p that contributes to papillary thyroid malignancy through DPP4

open access: yesClinical Epigenetics
Background Papillary thyroid carcinoma (PTC) is a common endocrine malignancy. Studies have indicated that estrogen can regulate the expression of miRNAs in numerous malignancies. MiR-570-3p has been shown to have a regulatory function in various cancers.
Xiarong Hu   +5 more
doaj   +1 more source

Ethyl 5-oxo-4-phenyl-5,6-dihydro-4H-1,3,4-oxadiazine-2-carboxylate

open access: yesActa Crystallographica Section E, 2014
The asymmetric unit of title compound, C12H12N2O4, consists of two independent molecules. In each molecule, the oxadiazine ring has a flattened envelope conformation with the methylene C atom as the flap atom, and the ethoxycarbonyl unit is in a syn ...
K. Shubakara   +4 more
doaj   +1 more source

On the Gierer-Meinhardt System with Saturation [PDF]

open access: yes, 2004
We consider the following shadow Gierer-Meinhardt system with saturation: \left\{\begin{array}{l} A_t=\epsilon^2 \Delta A -A + \frac{A^2}{ \xi (1+k A^2)} \ \ \mbox{in} \ \Omega \times (0, \infty),\\ \tau \xi_t= -\xi +\frac{1}{|\Omega|} \int_\Om A^2 ...
Wei, J, Winter, M
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Yield Loss Assessment and Determination of Control Thresholds for Anthracnose on Red Pepper

open access: yesResearch in Plant Disease, 2015
This study was carried out to develop control thresholds for anthracnose on red pepper. To investigate relationship between anthracnose incidence and diseased fruits, experimental plots with six treatments were established.
Ju-Hee Kim   +5 more
doaj   +1 more source

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