Results 41 to 50 of about 276,243 (334)
Journal of Experimental & Clinical Cancer Research, 2019 Background Glioma is the most common and lethal type of malignant brain tumor. Accumulating evidence has highlighted that RNA binding protein APOBEC1 complementation factor (A1CF) is involved in various cellular processes by modulating RNA expression ...
Yichen Song +10 more
doaj +1 more source
Investigative Ophthalmology and Visual Science, 2019 Purpose To elucidate the mechanism whereby miR-590-3p regulates pyroptosis in diabetic retinopathy (DR). Methods Human retinal microvascular endothelial cells (HRMECs) incubated with high glucose (HG) were used to establish cell models, and the ...
Chufeng Gu +8 more
semanticscholar +1 more source
miR-590-3p and Its Downstream Target Genes in HCC Cell Lines
Analytical Cellular Pathology, 2019 miRNAs are small non-coding RNA sequences of 18-25 nucleotides. They can regulate different cellular pathways by acting on tumor suppressors, oncogenes, or both.
Mennatallah Elfar, Asma Amleh
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Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the expression of long non-coding RNA (LncRNA) HCG11 and miR-590-3p in squamous carcinoma of cervix and paired adjacent tissues, and their correlation with patients' clinical data and prognosis.
CHEN Xiaojie, LIU Ping
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Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Markarian 590: the AGN awakens
Monthly Notices of the Royal Astronomical Society: LettersABSTRACT Changing-look active galactic nucleus Mkn 590 recently underwent a sudden ‘re-ignition’, marked by substantial increases in optical/ultravilolet (UV) and X-ray continuum flux since last couple of years. Swift-XRT observations revealed the re-emergence of a soft X-ray excess as the source transitioned from a low-flux state in ...
Biswaraj Palit +5 more
openaire +2 more sources
A miR-590/Acvr2a/Rad51b Axis Regulates DNA Damage Repair during mESC Proliferation
Stem Cell Reports, 2014 Embryonic stem cells (ESCs) enable rapid proliferation that also causes DNA damage. To maintain genomic stabilization during rapid proliferation, ESCs must have an efficient system to repress genotoxic stress.
Qidong Liu +5 more
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Systematic Comparison of Vectorization Methods in Classification Context
Applied Sciences, 2022 Natural language processing has been the subject of numerous studies in the last decade. These have focused on the various stages of text processing, from text preparation to vectorization to final text comprehension. The goal of vector space modeling is
Urszula Krzeszewska +2 more
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Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source