Results 41 to 50 of about 275,124 (334)

miR-590-3p Inhibits Pyroptosis in Diabetic Retinopathy by Targeting NLRP1 and Inactivating the NOX4 Signaling Pathway.

open access: yesInvestigative Ophthalmology and Visual Science, 2019
Purpose To elucidate the mechanism whereby miR-590-3p regulates pyroptosis in diabetic retinopathy (DR). Methods Human retinal microvascular endothelial cells (HRMECs) incubated with high glucose (HG) were used to establish cell models, and the ...
Chufeng Gu   +8 more
semanticscholar   +1 more source

Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background Glioma is the most common and lethal type of malignant brain tumor. Accumulating evidence has highlighted that RNA binding protein APOBEC1 complementation factor (A1CF) is involved in various cellular processes by modulating RNA expression ...
Yichen Song   +10 more
doaj   +1 more source

Systematic Comparison of Vectorization Methods in Classification Context

open access: yesApplied Sciences, 2022
Natural language processing has been the subject of numerous studies in the last decade. These have focused on the various stages of text processing, from text preparation to vectorization to final text comprehension. The goal of vector space modeling is
Urszula Krzeszewska   +2 more
doaj   +1 more source

miR-590-3p and Its Downstream Target Genes in HCC Cell Lines

open access: yesAnalytical Cellular Pathology, 2019
miRNAs are small non-coding RNA sequences of 18-25 nucleotides. They can regulate different cellular pathways by acting on tumor suppressors, oncogenes, or both.
Mennatallah Elfar, Asma Amleh
doaj   +1 more source

Expression of LncRNA HCG11 and miR-590-3p in Squamous Carcinoma of Cervix and Their Relationship with Prognosis

open access: yesZhongliu Fangzhi Yanjiu, 2018
Objective To investigate the expression of long non-coding RNA (LncRNA) HCG11 and miR-590-3p in squamous carcinoma of cervix and paired adjacent tissues, and their correlation with patients' clinical data and prognosis.
CHEN Xiaojie, LIU Ping
doaj   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Case Studies with the Contiki-NG Simulator to Design Strategies for Sensors’ Communication Optimization in an IoT-Fog Ecosystem

open access: yesSensors, 2023
With the development of mobile communications and the Internet of Things (IoT), IoT devices have increased, allowing their application in numerous areas of Industry 4.0.
Antonio Marcos Almeida Ferreira   +3 more
doaj   +1 more source

Markarian 590: the AGN awakens

open access: yesMonthly Notices of the Royal Astronomical Society: Letters
ABSTRACT Changing-look active galactic nucleus Mkn 590 recently underwent a sudden ‘re-ignition’, marked by substantial increases in optical/ultravilolet (UV) and X-ray continuum flux since last couple of years. Swift-XRT observations revealed the re-emergence of a soft X-ray excess as the source transitioned from a low-flux state in ...
Biswaraj Palit   +5 more
openaire   +2 more sources

LncRNA NEAT1 promotes apoptosis and inflammation in LPS-induced sepsis models by targeting miR-590-3p

open access: yesExperimental and Therapeutic Medicine, 2020
Sepsis is a complication of infection caused by disease or trauma. Increasing evidence have shown that long noncoding RNAs (lncRNAs) are involved in the regulation of sepsis. However, the mechanism of lncRNA nuclear enriched abundant transcript 1 (NEAT1)
Lingling Liu   +5 more
semanticscholar   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

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