Results 31 to 40 of about 1,334,870 (300)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

miR-590-3p and Its Downstream Target Genes in HCC Cell Lines

open access: yesAnalytical Cellular Pathology, 2019
miRNAs are small non-coding RNA sequences of 18-25 nucleotides. They can regulate different cellular pathways by acting on tumor suppressors, oncogenes, or both.
Mennatallah Elfar, Asma Amleh
doaj   +1 more source

Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background Glioma is the most common and lethal type of malignant brain tumor. Accumulating evidence has highlighted that RNA binding protein APOBEC1 complementation factor (A1CF) is involved in various cellular processes by modulating RNA expression ...
Yichen Song   +10 more
doaj   +1 more source

Fair Trade City Subsidization and WTO Agreement Violation [PDF]

open access: yes, 2006
Numerous local governments in the UK have achieved the designation Fairtrade City for their provision of special assistance to Fairtrade certified goods “ which originate from producers in the developing world who enjoy a higher wage and healthy living ...
Collins, D. A.
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Case Studies with the Contiki-NG Simulator to Design Strategies for Sensors’ Communication Optimization in an IoT-Fog Ecosystem

open access: yesSensors, 2023
With the development of mobile communications and the Internet of Things (IoT), IoT devices have increased, allowing their application in numerous areas of Industry 4.0.
Antonio Marcos Almeida Ferreira   +3 more
doaj   +1 more source

The Education Maintenance Allowance (Wales) Scheme 2010 [PDF]

open access: yes, 2010
Consultation document seeking views on the draft Education Maintenance Allowance (Wales) Scheme ...

core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Expression of LncRNA HCG11 and miR-590-3p in Squamous Carcinoma of Cervix and Their Relationship with Prognosis

open access: yesZhongliu Fangzhi Yanjiu, 2018
Objective To investigate the expression of long non-coding RNA (LncRNA) HCG11 and miR-590-3p in squamous carcinoma of cervix and paired adjacent tissues, and their correlation with patients' clinical data and prognosis.
CHEN Xiaojie, LIU Ping
doaj   +1 more source

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