Results 11 to 20 of about 322,746 (281)
BMC Cancer, 2023 Background There is considerable evidence that microRNAs (miRNAs) regulate several key tumor-associated genes/pathways and may themselves have a dual regulatory function either as tumor suppressors or oncogenic miRNA, depending on the tumor type ...
Alaa Ibrahem Youssef +2 more
doaj +1 more source
miR-590-5p mediates mitochondrial respiration, proliferation, and apoptosis in thyroid carcinoma cells via fibroblast growth factor receptor substrate 2 [PDF]
Archives of Endocrinology and MetabolismObjective: Thyroid carcinoma (TC) is the most common cancer of the endocrine system. Dysregulation of microRNA-590-5p (miR-590-5p) has been associated with various malignancies. Targeting mitochondrial respiration is beneficial in treating TC. This study
Penghui Wang +5 more
doaj +1 more source
Frontiers in Genetics, 2021 Circular RNA (circRNA) is an important factor for regulating the progression of many cardiovascular diseases, including acute myocardial infarction (AMI). However, the role of circ_0124644 in AMI progression remains unclear.
Juan Tan +7 more
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The miR-590/Acvr2a/Terf1 Axis Regulates Telomere Elongation and Pluripotency of Mouse iPSCs
Stem Cell Reports, 2018 Summary: During reprogramming, telomere re-elongation is important for pluripotency acquisition and ensures the high quality of induced pluripotent stem cells (iPSCs), but the regulatory mechanism remains largely unknown.
Qidong Liu +10 more
doaj +1 more source
Central European Journal of Immunology, 2021 Oxidative low-density lipoprotein (ox-LDL) is thought to induce vascular endothelial cell injury, which contributes to the aetiopathogenesis of atherosclerosis (AS).
Jinpeng Zhong +7 more
doaj +1 more source
, 2023 Additional file 2: Figure S2. Sequence alignment between miR-590-3p and N-cadherin but not Vimentin. TargetScan shows that the mesenchymal marker N-cadherin harbours three different binding sites with miR-590-3p in its 3′UTR, while no binding was shown ...
Alaa Ibrahem Youssef (15406260) +2 more
core +1 more source
Kaohsiung Journal of Medical Sciences, 2020 The ubiquitin conjugating enzyme E2 N (UBE2N) has been reported to be involved in the tumorigenesis of several tumors, but its function in cervical carcinoma has not been investigated yet.
Ting‐Ting Song, Fei Xu, Wei Wang
doaj +1 more source
Autoimmunity, 2021 Objective Asthma is a prevalent chronic inflammatory airway disease that is characterised by airway remodelling and airway hyperresponsiveness. Abnormal proliferation and migration of airway smooth muscle cells (ASMCs) contribute to airway remodelling in
Wen-Lan Wang +5 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2021 Radiotherapeutic resistance is a major obstacle for the effective treatment of colorectal cancer (CRC). MicroRNAs (miRNAs) play a critical role in chemoresistance and radioresistance.
Xijuan Chen +7 more
doaj +1 more source
Assessing chronic rhinosinusitis with nasal polyps severity by “Japanese epidemiological survey of refractory eosinophilic chronic rhinosinusitis” algorithm [PDF]
Exploration of Asthma & Allergy, 2023 Aim: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex disease with different subtypes that affect patients’ quality of life. This study aim to evaluate the severity of CRSwNP and the risk of treatment resistance using the “Japanese ...
Sérgio Duarte Dortas Jr +7 more
doaj +1 more source