Results 21 to 30 of about 290,887 (206)

Khosrow II (590–628 CE)

open access: yesEncyclopedia, 2022
Khosrow II (r. 590–628 CE) was the last great Sasanian king who took the throne with the help of the Romans and broke with dynastic religious preferences as he became married to a Christian empress.
Mahdi Motamedmanesh, Samira Royan
doaj   +1 more source

Long non‐coding RNA ESCCAL‐1/miR‐590/LRP6 signaling pathway participates in the progression of esophageal squamous cell carcinoma

open access: yesCancer Medicine, 2023
Background Long non‐coding RNAs (lncRNAs) have critical functions within esophageal squamous cell carcinoma (ESCC). However, the function and mechanism underlying ESCC‐associated lncRNA‐1 (ESCCAL‐1) in ESCC tumorigenesis have not been well clarified ...
Hongya Guan   +8 more
doaj   +1 more source

Additional file 1 of Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

open access: yes, 2023
Additional file 1: Figure S1. miR-590-3p directly targets EMT-TF SLUG, ZEB1, and ZEB2 in HCC, as determined by bioinformatics analysis (A) CSmiRTar database analysis showing SLUG, ZEB1 and ZEB2 as miR-590-3p potential target genes.
Alaa Ibrahem Youssef (15406260)   +2 more
core   +1 more source

MiR-590 Suppresses Proliferation and Induces Apoptosis in Pancreatic Cancer by Targeting High Mobility Group A2

open access: yesTechnology in Cancer Research & Treatment, 2020
Background: Pancreatic ductal adenocarcinoma is a common malignancy with high morbidity. MicroRNAs have been demonstrated to be critical posttranscriptional regulators in tumorigenesis.
Ya-Dong Wang MD   +3 more
doaj   +1 more source

Circ_0124644 Serves as a ceRNA for miR-590-3p to Promote Hypoxia-Induced Cardiomyocytes Injury via Regulating SOX4

open access: yesFrontiers in Genetics, 2021
Circular RNA (circRNA) is an important factor for regulating the progression of many cardiovascular diseases, including acute myocardial infarction (AMI). However, the role of circ_0124644 in AMI progression remains unclear.
Juan Tan   +7 more
doaj   +1 more source

Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

open access: yesBMC Cancer, 2023
Background There is considerable evidence that microRNAs (miRNAs) regulate several key tumor-associated genes/pathways and may themselves have a dual regulatory function either as tumor suppressors or oncogenic miRNA, depending on the tumor type ...
Alaa Ibrahem Youssef   +2 more
doaj   +1 more source

The miR-590/Acvr2a/Terf1 Axis Regulates Telomere Elongation and Pluripotency of Mouse iPSCs

open access: yesStem Cell Reports, 2018
Summary: During reprogramming, telomere re-elongation is important for pluripotency acquisition and ensures the high quality of induced pluripotent stem cells (iPSCs), but the regulatory mechanism remains largely unknown.
Qidong Liu   +10 more
doaj   +1 more source

Additional file 2 of Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

open access: yes, 2023
Additional file 2: Figure S2. Sequence alignment between miR-590-3p and N-cadherin but not Vimentin. TargetScan shows that the mesenchymal marker N-cadherin harbours three different binding sites with miR-590-3p in its 3′UTR, while no binding was shown ...
Alaa Ibrahem Youssef (15406260)   +2 more
core   +1 more source

LncRNA ZEB1-AS1 knockdown alleviates oxidative low-density lipoprotein-induced endothelial cell injury via the miR-590-5p/ HDAC9 axis

open access: yesCentral European Journal of Immunology, 2021
Oxidative low-density lipoprotein (ox-LDL) is thought to induce vascular endothelial cell injury, which contributes to the aetiopathogenesis of atherosclerosis (AS).
Jinpeng Zhong   +7 more
doaj   +1 more source

Inhibiting ubiquitin conjugating enzyme E2 N by microRNA‐590‐3p reduced cell growth of cervical carcinoma

open access: yesKaohsiung Journal of Medical Sciences, 2020
The ubiquitin conjugating enzyme E2 N (UBE2N) has been reported to be involved in the tumorigenesis of several tumors, but its function in cervical carcinoma has not been investigated yet.
Ting‐Ting Song, Fei Xu, Wei Wang
doaj   +1 more source

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