Results 1 to 10 of about 322,746 (281)

Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis.

open access: yesPLoS ONE, 2016
MicroRNAs (miRNAs) are recognized as important regulators of cardiac development, hypertrophy and fibrosis. Recent studies have demonstrated that genetic variations which cause alterations in miRNA:target interactions can lead to disease. We hypothesized
Xiaoping Lin   +15 more
doaj   +2 more sources

MiR-590-3p suppresses hepatocellular carcinoma growth by targeting TEAD1

open access: yesTumor Biology, 2017
MicroRNA signature is altered in different disease states including cancer, and some microRNAs act as oncogenes or tumor suppressors. MiR-590-3p has been shown to be involved in human cancer progression.
Xin Ge, Liansheng Gong
doaj   +2 more sources

Exosomal miR-590-5p in Serum as a Biomarker for the Diagnosis and Prognosis of Gastric Cancer

open access: yesFrontiers in Molecular Biosciences, 2021
The purpose of this study is to explore the expression of miRNA-590-5p, an exosome of gastric cancer (GC), and to evaluate the suitability of miR-590-5p, an exosome with its own clinical characteristics. Serum samples from 168 gastric cancer patients and
Guo-Dian Zheng   +9 more
doaj   +1 more source

MicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice. [PDF]

open access: yesPLoS ONE, 2015
Recent studies have suggested that miR-590 may play critical roles in cardiovascular disease. This study was designed to determine the effects of miR-590 on lipoprotein lipase (LPL) expression and development of atherosclerosis in apolipoprotein E ...
Ping-Ping He   +19 more
doaj   +1 more source

miR-590–5p: A double-edged sword in the oncogenesis process

open access: yesCancer Treatment and Research Communications, 2022
Accumulating evidence suggests the critical role of miR-590–5p in various aspects of cellular homeostasis, including cancer. Furthermore, we and others have recently demonstrated that miRNA-590–5p acts as an oncogene in some cancers while it acts as a ...
Tushar Singh Barwal   +12 more
doaj   +1 more source

miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1

open access: yesAnalytical Cellular Pathology, 2022
Alzheimer’s disease (AD) is one common degenerative disorder. However, the effects of miR-590-5p on AD and the mechanism on modulation of AD development were unclear.
Lin Shang   +6 more
doaj   +1 more source

Long non‐coding RNA ESCCAL‐1/miR‐590/LRP6 signaling pathway participates in the progression of esophageal squamous cell carcinoma

open access: yesCancer Medicine, 2023
Background Long non‐coding RNAs (lncRNAs) have critical functions within esophageal squamous cell carcinoma (ESCC). However, the function and mechanism underlying ESCC‐associated lncRNA‐1 (ESCCAL‐1) in ESCC tumorigenesis have not been well clarified ...
Hongya Guan   +8 more
doaj   +1 more source

Khosrow II (590–628 CE)

open access: yesEncyclopedia, 2022
Khosrow II (r. 590–628 CE) was the last great Sasanian king who took the throne with the help of the Romans and broke with dynastic religious preferences as he became married to a Christian empress.
Mahdi Motamedmanesh, Samira Royan
doaj   +1 more source

MiR-590 Suppresses Proliferation and Induces Apoptosis in Pancreatic Cancer by Targeting High Mobility Group A2

open access: yesTechnology in Cancer Research & Treatment, 2020
Background: Pancreatic ductal adenocarcinoma is a common malignancy with high morbidity. MicroRNAs have been demonstrated to be critical posttranscriptional regulators in tumorigenesis.
Ya-Dong Wang MD   +3 more
doaj   +1 more source

Additional file 1 of Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

open access: yes, 2023
Additional file 1: Figure S1. miR-590-3p directly targets EMT-TF SLUG, ZEB1, and ZEB2 in HCC, as determined by bioinformatics analysis (A) CSmiRTar database analysis showing SLUG, ZEB1 and ZEB2 as miR-590-3p potential target genes.
Alaa Ibrahem Youssef (15406260)   +2 more
core   +1 more source

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