Results 61 to 70 of about 276,243 (334)

Hsa-miR-590-5p Interaction with SMAD3 Transcript Supports Its Regulatory Effect on The TGFβ Signaling Pathway

open access: yesCell Journal, 2016
Objective: SMAD proteins are the core players of the transforming growth factor-beta (TGFβ) signaling pathway, a pathway which is involved in cell proliferation, differentiation and migration.
Meisam Jafarzadeh, Bahram M. Soltani
doaj  

Influence of Temperature on Scratch and Wear Properties of Technical Thermoplastics: Implications for Material Selection

open access: yesAdvanced Engineering Materials, EarlyView.
The share of technical thermoplastics is expected to grow further in the e‐mobility segment. In this study, a detailed temperature‐based tribological characterization of technical thermoplastics is performed. The tribological properties are discussed in terms of the dynamic mechanical properties of polymers at different ambient temperatures. A proof of
Harsha Raghuram   +2 more
wiley   +1 more source

Long non-coding RNA NORAD regulates angiogenesis of human umbilical vein endothelial cells via miR-590-3p under hypoxic conditions

open access: yesMolecular Medicine Reports, 2020
Dysregulation of angiogenesis can be caused by hypoxia, which may result in severe diseases of the heart, including coronary artery disease. Hypoxia-inducible factor 1 (HIF-1) modulates angiogenesis via the regulation of several angiogenic factors ...
Xiaoxue Zhao   +3 more
semanticscholar   +1 more source

Antimicrobial Titanium–Copper Alloys: The Role of Microstructure in Arc‐Melted Compositions

open access: yesAdvanced Engineering Materials, EarlyView.
Copper‐containing titanium alloys show promise in combating orthopedic implant infections. This study explores the influence of heat treatment on Ti‐11.5Cu and Ti‐33Cu alloys, revealing that larger Ti2Cu precipitates (≈5 μm) enhance antimicrobial efficacy through increased surface contact. Results suggest contact sterilization is the primary mechanism,
Daisy Rabbitt   +5 more
wiley   +1 more source

Exosomal miR-590-3p derived from cancer-associated fibroblasts confers radioresistance in colorectal cancer

open access: yesMolecular Therapy: Nucleic Acids, 2021
Radiotherapeutic resistance is a major obstacle for the effective treatment of colorectal cancer (CRC). MicroRNAs (miRNAs) play a critical role in chemoresistance and radioresistance.
Xijuan Chen   +7 more
doaj  

Investigation of 3D Wave Propagation in Foam‐Core Functionally Graded Material Magneto‐Piezoelectric Smart Nanoplates

open access: yesAdvanced Engineering Materials, EarlyView.
This study reveals how wave propagation in FG‐MEE nanoplates can be tuned via material gradients, porosity, and external fields. Using NSGT and Hamilton's principle, analytical solutions capture key dispersion behaviors. Findings highlight the potential of smart nanoplates for adaptive control in high‐performance applications like sonar and aerospace ...
Mustafa Buğday, Ismail Esen
wiley   +1 more source

Long tailed trions in monolayer MoS2: Temperature dependent asymmetry and resulting red-shift of trion photoluminescence spectra

open access: yesScientific Reports, 2017
Monolayer molybdenum disulfide (MoS2) has emerged as a model system for studying many-body physics because the low dimensionality reduces screening leading to tightly bound states stable at room temperature. Further, the many-body states possess a pseudo-
Jason W. Christopher   +2 more
doaj   +1 more source

Ag Cluster‐Modified K0.5Na0.5NbO3 Piezocatalyst for Enhanced Electrochemical Dinitrogen Reduction Reaction

open access: yesAdvanced Engineering Materials, EarlyView.
Ag cluster‐modified K0.5Na0.5NbO3 acts as an efficient piezocatalyst for electrochemical N2 reduction, enhanced by built‐in electric fields under mechanical actuation. Comparative studies between static and actuated electrodes reveal improved performance under dynamic conditions.
Benedict Witulski   +7 more
wiley   +1 more source

miR-590-3p Targets Cyclin G2 and FOXO3 to Promote Ovarian Cancer Cell Proliferation, Invasion, and Spheroid Formation

open access: yesInternational Journal of Molecular Sciences, 2019
Ovarian cancer is the leading cause of death from gynecological cancers. MicroRNAs (miRNAs) are small, non-coding RNAs that interact with the 3′ untranslated region (3′ UTR) of target genes to repress their expression.
M. Salem   +3 more
semanticscholar   +1 more source

Engineering the Hierarchical Porosity of Granular Hydrogel Scaffolds Using Porous Microgels to Improve Cell Recruitment and Tissue Integration

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski   +9 more
wiley   +1 more source

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