Results 181 to 190 of about 24,703 (234)

6-MERCAPTOPURINE AND ANTIVIRAL NUCLEOSIDE ANALOGUES

Lancet, The, 1987
Per Magne Ueland
exaly   +3 more sources

6-MERCAPTOPURINE IN POLYRADICULONEUROPATHY

Lancet, The, 1965
D.G. Colin-Jones, K.W.G. Heathfield
exaly   +2 more sources

Teratogen update: Azathioprine and 6‐mercaptopurine

Teratology, 2002
Azathioprine (AZA) and its active metabolite, 6-mercaptopurine (6-MP), are purine analogues that interfere with the synthesis of adenine and guanine ribonucleosides. These ribonucleosides are important precursors of DNA and RNA. Because AZA and 6-MP act predominantly on rapidly dividing cells such as the T lymphocytes, these drugs are not only ...
Janine E, Polifka, J M, Friedman
openaire   +2 more sources

6-Mercaptopurine Therapy

2007
6-Mercaptopurine (6-MP) and its parent drug azathioprine (AZA) are well known for their immunosuppressive and lymphocytotoxic properties. These antimetabolite drugs have been shown to suppress disease activity in up to 70% of children with moderate to severe IBD; among these patients, 50% will achieve a clinical response after 4 months of continuous ...
openaire   +1 more source

6‐MERCAPTOPURINE ADMINISTRATION TO NZB MICE

Australian Journal of Experimental Biology and Medical Science, 1968
SummaryAn intensive course of 6‐Mercaptopurine therapy in NZB mice immediately before the overt onset of their autoimmune haemolytic disorder did not delay or modify the subsequent development of antierythrocyte auto‐ antibody or of anaemia.Anaemic mice tolerated the drug poorly.
openaire   +2 more sources

6-Mercaptopurine

Reactions, 1981
openaire   +3 more sources

CLINICAL STUDIES ON 6‐MERCAPTOPURINE

Annals of the New York Academy of Sciences, 1954
J H, BURCHENAL, R R, ELLISON, M L, MURPHY, D A, KARNOFSKY, M P, SYKES, T C, TAN, A C, MERMANN, M, YUCEOGLU, W P, MYERS, I, KRAKOFF, N, ALBERSTADT   +10 more
openaire   +2 more sources

6-Mercaptopurine

1970
Robert B. Livingston, Stephen K. Carter
openaire   +1 more source

MICROBIOLOGICAL EFFECTS OF 6‐MERCAPTOPURINE

Annals of the New York Academy of Sciences, 1954
G B, ELION, S, SINGER, G H, HITCHINGS
openaire   +2 more sources

CLINICAL EVALUATION OF 6‐MERCAPTOPURINE

Annals of the New York Academy of Sciences, 1954
A, SAWITSKY, C R, REAM
openaire   +2 more sources