Results 171 to 180 of about 88,642,428 (226)
Some of the next articles are maybe not open access.
Transplantation, 1973
SUMMARY A comparative study of the immunosuppressive activities of 6-mercaptopurine and its derivative azathioprine has been performed. It has been shown that in mice and rats, 6-mercaptopurine is markedly superior to azathioprine in reducing the number of spleen hemolytic plaque-forming cells when injected by parenteral routes, whereas azathioprine ...
F, Spreafico +5 more
openaire +2 more sources
SUMMARY A comparative study of the immunosuppressive activities of 6-mercaptopurine and its derivative azathioprine has been performed. It has been shown that in mice and rats, 6-mercaptopurine is markedly superior to azathioprine in reducing the number of spleen hemolytic plaque-forming cells when injected by parenteral routes, whereas azathioprine ...
F, Spreafico +5 more
openaire +2 more sources
Pediatrics International, 2001
Abstract Background : The poor absorption of orally administered 6‐mercaptopurine (6MP) causes a wide variation in its cytotoxic efficacy. An i.v. dosage form would eliminate this problem. Our objective was to compare the pharmacokinetics of 6MP administered orally with those of an i.v.
H, Mawatari +4 more
openaire +2 more sources
Abstract Background : The poor absorption of orally administered 6‐mercaptopurine (6MP) causes a wide variation in its cytotoxic efficacy. An i.v. dosage form would eliminate this problem. Our objective was to compare the pharmacokinetics of 6MP administered orally with those of an i.v.
H, Mawatari +4 more
openaire +2 more sources
2007
6-Mercaptopurine (6-MP) and its parent drug azathioprine (AZA) are well known for their immunosuppressive and lymphocytotoxic properties. These antimetabolite drugs have been shown to suppress disease activity in up to 70% of children with moderate to severe IBD; among these patients, 50% will achieve a clinical response after 4 months of continuous ...
openaire +1 more source
6-Mercaptopurine (6-MP) and its parent drug azathioprine (AZA) are well known for their immunosuppressive and lymphocytotoxic properties. These antimetabolite drugs have been shown to suppress disease activity in up to 70% of children with moderate to severe IBD; among these patients, 50% will achieve a clinical response after 4 months of continuous ...
openaire +1 more source
6‐MERCAPTOPURINE THERAPY IN LEUKEMIA
Annals of the New York Academy of Sciences, 1954J M, HILL, J, LAJOUS
openaire +2 more sources
MICROBIOLOGICAL EFFECTS OF 6‐MERCAPTOPURINE
Annals of the New York Academy of Sciences, 1954G B, ELION, S, SINGER, G H, HITCHINGS
openaire +2 more sources
THE FATE OF 6‐MERCAPTOPURINE IN MAN
Annals of the New York Academy of Sciences, 1954L, HAMILTON, G B, ELION
openaire +2 more sources