Results 91 to 100 of about 985,419 (304)

Independent Prognostic Significance of Perforation in Colorectal Cancer: Insights From a Propensity Score‐Matched Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
Perforated colorectal cancer (PCC) is considered to have a poor prognosis; however, it remains unclear whether this is attributable to perforation itself or to perforation‐related clinicopathological factors. In this study, we analyzed prognosis using propensity score matching with perforation‐related factors and demonstrated that perforation is an ...
Yoshiaki Fujii, Shuhei Ueno, Yoshinaga Aoyama, Hiroyuki Imafuji, Takahisa Hirokawa, Hirotaka Miyai, Masahiro Kimura, Kenji Kobayashi, Shuji Takiguchi   +8 more
wiley   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Poria cocos Ethanol Extract Restores MK-801-Induced Cytoskeleton Regulation in Neuro2A and IMR-32 Cells and Locomotor Hyperactivity in C57BL/6 Mice by Modulating the Rho Signaling Pathway

Current Issues in Molecular Biology
Poria cocos extract attenuates MK-801-induced hyperactivity via RhoA/ROCK1 pathway modulation in mice. Background/Objectives: Poria cocos (P. cocos), a traditional East Asian medicinal mushroom, serves as a medicine and nutritional supplement, has been ...
Ya-Ying Chang, Cheng-Wei Lu, Tzu-Yu Lin, I-Shiang Tzeng, Yi-Chyan Chen, Mao-Liang Chen   +5 more
doaj   +1 more source

Prognostic Significance of Portal Vein Tumor Thrombus in Pancreatic Ductal Adenocarcinoma Treated With Chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To examine the significance of portal vein tumor thrombus (PVTT) as a prognostic factor for patients with pancreatic ductal adenocarcinoma (PDAC) treated with chemoradiotherapy (CRT) followed by surgery. Methods The study retrospectively examined 313 patients with borderline resectable (BR) or locally advanced (LA) PDAC who underwent CRT ...
Aoi Hayasaki, Motonori Nagata, Miki Usui, Hiroshi Imai, Yusuke Iizawa, Akihiro Tanemura, Yasuhiro Murata, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno   +9 more
wiley   +1 more source

Olanzapine Reverses MK-801-Induced Cognitive Deficits and Region-Specific Alterations of NMDA Receptor Subunits

Frontiers in Behavioral Neuroscience, 2018
Cognitive dysfunction constitutes an essential component in schizophrenia for its early presence in the pathophysiology of the disease and close relatedness to life quality of patients.
Xiao Liu, Xiao Liu, Xiao Liu, Jitao Li, Chunmei Guo, Hongli Wang, Yaxin Sun, Han Wang, Yun-Ai Su, Keqing Li, Keqing Li, Tianmei Si   +11 more
doaj   +1 more source

Effect of Broad‐Spectrum Antibiotic Prophylaxis on Post‐Pancreatoduodenectomy Infectious Complications: Nationwide Inpatient Database Study in Japan

Annals of Gastroenterological Surgery, EarlyView.
Using a nationwide Japanese inpatient database, we evaluated whether broad‐spectrum antibiotic prophylaxis improves postoperative outcomes after pancreatoduodenectomy compared with narrow‐spectrum antibiotics. In propensity score–weighted analyses of 45 099 patients, broad‐spectrum prophylaxis was associated with significantly lower rates of intra ...
Hiroki Kitagawa, Shotaro Aso, Yuki Hirano, Kenichiro Uemura, Keita Kouzu, Satoru Matsuda, Hiroki Matsui, Kiyohide Fushimi, Junichi Sasaki, Yuko Kitagawa, Hideo Yasunaga   +10 more
wiley   +1 more source

Effects of haloperidol inhalation on MK-801- and memantine-induced locomotion in mice

Libyan Journal of Medicine, 2020
The administration of therapeutic agents is difficult in many patients, such as patients with post-operative delirium or dementia or patients with schizophrenia, who are upset in an emergency room.
Hiroshi Ueno, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yu Takahashi, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara   +8 more
doaj   +1 more source

Impact of Recanalization on Liver Hypertrophy after Portal Vein Embolization and the Role of Re‐Embolization

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study of 249 patients undergoing hepatectomy after right portal vein embolization (PVE) demonstrated that major recanalization–defined as recanalization more than one segment within the embolized liver–was associated with impaired regeneration of the future liver remnant (FLR).
Masao Uemura, Shimpei Otsuka, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Rui Sato, Takeshi Aramaki, Akifumi Notsu, Katsuhiko Uesaka, Teiichi Sugiura   +9 more
wiley   +1 more source

Vortioxetine Differentially Modulates MK-801-Induced Changes in Visual Signal Detection Task Performance and Locomotor Activity

Frontiers in Pharmacology, 2018
Attention impairment is a common feature of Major Depressive Disorder (MDD), and MDD-associated cognitive dysfunction may play an important role in determining functional status among this patient population.
Todd M. Hillhouse, Christina R. Merritt, Douglas A. Smith, Manuel Cajina, Connie Sanchez, Joseph H. Porter, Alan L. Pehrson   +6 more
doaj   +1 more source

MARKETING ACTIVITIES DURING THE INNOVATION PROCESS: INTERACTION OF RESEARCH AND DEVELOPMENT [PDF]

, 2012
According to the aberrant-salience hypothesis, attribution of motivational salience is severely disrupted in patients with schizophrenia. To provide a translational approach for investigating underlying mechanisms, neural correlates of salience ...
Habel, Ute, Mößnang, Carolin Ulrike, Schneider, Frank, Siegel, Steven J.   +3 more
core   +1 more source