Results 41 to 50 of about 985,419 (304)
Hepatology Communications, 2022 Racial/ethnic minorities experience higher rates of wait‐list mortality and longer waiting times on the liver transplant wait list. We hypothesized that racial/ethnic minorities may encounter greater logistical barriers to maintaining “readiness” on the ...
Jin Ge +3 more
doaj +1 more source
Mechanism of allosteric activation of SIRT6 revealed by the action of rationally designed activators
Acta Pharmaceutica Sinica B, 2021 The recent discovery of activator compounds binding to an allosteric site on the NAD+-dependent protein lysine deacetylase, sirtuin 6 (SIRT6) has attracted interest and presents a pharmaceutical target for aging-related and cancer diseases.
Shaoyong Lu +6 more
doaj +1 more source
Mitochondrial genetics of alloplasmic male-sterile Brassica napus lines [PDF]
, 2005 Reliable and economical production of hybrid (F1) varieties requires efficient means to control pollination. The predominant system for pollination control of most field crops today is cytoplasmic male sterility (CMS).
Leino, Matti
core
Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat [PDF]
, 2007 The administration of noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists such as phencyclidine and ketamine has been shown to increase the extracellular concentration of glutamate and serotonin (5-HT) in the medial prefrontal cortex (mPFC ...
López-Gil, Xavier +5 more
core +1 more source
Shaping Ti3C2 MXene Nanospheres for Precision Near‐Infrared Photothermal Therapy
Advanced Functional Materials, EarlyView.In this study, we report producing spherical MXenes via fs laser fragmentation of Ti3C2 flakes in liquid medium. The nanoparticles demonstrated pronounced light absorption and high photothermal conversion efficiencies of 68% and 63% under heating with NIR‐I and NIR‐II lasers, respectively.
Julia S. Babkova +21 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2019 MK-801, also known as dizocilpine, is a non-competitive N-methyl-D-aspartic acid (NMDA) receptor antagonist that induces schizophrenia-like symptoms. Our previous study showed that brain-derived neurotrophic factor (BDNF) signaling was upregulated in ...
Wenjuan Yu +12 more
doaj +1 more source
FOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801 [PDF]
, 2013 BACKGROUND: Accumulating evidence has suggested the importance of glutamate signaling in cancer growth, yet the signaling pathway has not been fully elucidated.
Fuminori Yamaguchi +6 more
core +1 more source
Advanced Functional Materials, EarlyView.Synthesis and characterization of light‐responsive donor–acceptor Stenhouse adducts (DASA)‐coated chlorhexidine‐loaded silica nanoparticles. Such a controllable drug‐delivery system enables the release of the antimicrobial drug on demand and in consecutive cycles, thereby maintaining the concentration within the therapeutic window.
Michèle Clerc +9 more
wiley +1 more source
European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism
BJS (British Journal of Surgery), EarlyView., 2020 Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz +3 more
wiley +1 more source
Review of: Eleanor Singer & Phyllis M. Endreny, Reporting on Risk [PDF]
, 1994 Review of: Eleanor Singer & Phyllis M. Endreny, Reporting on Risk (Russell Sage Foundation 1993). Acknowledgments, index, notes, preface, references, tables. LC 92-40130; ISBN 0-87154-801-1. [256 pp. Cloth $24.95. 112 East 64th Street, New York NY 10021.
Singer, Mladen
core +1 more source