Results 61 to 70 of about 985,419 (304)

Cannabidiol Attenuates Sensorimotor Gating Disruption and Molecular Changes Induced by Chronic Antagonism of NMDA receptors in Mice [PDF]

, 2015
Background: Preclinical and clinical data suggest that cannabidiol (CBD), a major non-psychotomimetic compound from Cannabis sativa, induces antipsychotic-like effects.
Del Bel, Elaine A., Ferreira, Frederico R., Gomes, Felipe V., Guimarães, Francisco S., Issy, Ana Carolina, Viveros, María Paz   +5 more
core   +2 more sources

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Nanoarchitectonics of Porous Carbons Templated by Inorganic Metal Oxides and Alkali Metal Salts for Energy and Environmental Applications

Advanced Science, EarlyView.
This review explores inorganic metal oxides and metal salt nanoparticles templated porous carbons, highlighting their synthesis, structural features, and performance in energy and environmental applications. It critically compares template types, porosity control, and functional outcomes across recent literature.
Gurwinder Singh, Jibi Kunjumon, Harleen Kaur, Narinder Singh, Gregory Franklin, Arpita Pandey Tiwari, Lukas Van Zweiten, John Kennedy, Ajayan Vinu   +8 more
wiley   +1 more source

The Effect of Subchronic Dosing of Ciproxifan and Clobenpropit on Dopamine and Histamine Levels in Rats

Journal of Experimental Neuroscience, 2015
The present study was designed to investigate the effect of once daily for 7-day (subchronic treatment) dosing of histamine H 3 receptor antagonists, ciproxifan (CPX) (3 mg/kg, i.p.), and clobenpropit (CBP) (15 mg/kg, i.p), including clozapine (CLZ) (3.0
D. Mahmood, K.K. Pillai, R. Khanam, K. Jahan, D. Goswami, M. Akhtar   +5 more
doaj   +1 more source

Decreased MK-801 Binding in Discrete Hippocampal Regions of Prion-Infected Mice

Neurobiology of Disease, 2001
The neurochemical alterations associated with neurodegeneration in prion diseases are not well defined. It is therefore of interest to study the influence of prion infection on messenger molecules and their receptors.
M. Diez, S.J. DeArmond, D. Groth, S.B. Prusiner, T. Hökfelt   +4 more
doaj   +1 more source

The ITGB2‐COPS3‐SOX2 Axis and SOX2 Liquid‐Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness

Advanced Science, EarlyView.
Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo, Zhiqing Zhao, Wei Wang, Jianfang Niu, Bing Wang, Yunfei Lin, Wei Guo, Taiqiang Yan   +7 more
wiley   +1 more source

Atmospheric Water Sorption Kinetics in Powder and Monolithic Metal–Organic Frameworks

Advanced Materials Interfaces
Metal–organic frameworks (MOFs) have been widely applied for adsorption applications owing to their high surface area and porosity. In this paper, the atmospheric water adsorption kinetics in a prototypical MOF with two forms, that is, powder and ...
Jiawang Li, Guang Wang, Hongzhao Fan, Zhigang Li, Chi Yan Tso, Yanguang Zhou   +5 more
doaj   +1 more source

Synthesis of Defective MOF-801 via Air–Liquid Segmented Flow for Catalytic Transfer Hydrogenation of Furfural

Molecules
As one of the most important platform chemicals, furfural (FAL) can be converted into high-value-added products such as furfuryl alcohol (FOL) through multiple pathways.
Yuxuan Liu, Qiuju Fu, Weijing Niu, Yingxin Zhang, Wenpeng Xie, Huimin Jiang, Liting Yan, Guangda Li, Xuebo Zhao   +8 more
doaj   +1 more source

Relationship of Nitrogen Use Efficiency with the Activities of Enzymes Involved in Nitrogen Uptake and Assimilation of Finger Millet Genotypes Grown under Different Nitrogen Inputs

The Scientific World Journal, 2012
Nitrogen responsiveness of three-finger millet genotypes (differing in their seed coat colour) PRM-1 (brown), PRM-701 (golden), and PRM-801 (white) grown under different nitrogen doses was determined by analyzing the growth, yield parameters and ...
Nidhi Gupta, Atul K. Gupta, Vikram S. Gaur, Anil Kumar   +3 more
doaj   +1 more source

A smart radar absorber based on the phase-switched screen [PDF]

, 2005
Although conventional (i.e., passive) radar absorbers are widely used for modifying the radar cross-section (RCS) of current military platforms, such absorbers may not have adequate performance to satisfy future requirements.
Chambers, B., Tennant, A.
core   +1 more source