Results 61 to 70 of about 1,623,979 (311)

Feedback control of the COVID-19 outbreak based on active disturbance rejection control

open access: yesApplied Mathematics in Science and Engineering
The outbreak of COVID-19 causes a serious threat to human health and life around the world and puts enormous pressure on the healthcare system. The lockdown policy has effectively reduced the number of cases and suppressed the spread of the COVID-19 ...
Haonan Zhang, Wen Tan, Mei Yu, Yiming Li
doaj   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

open access: yesFEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos   +3 more
wiley   +1 more source

Electroanalysis of Naringin at Electroactivated Pencil Graphite Electrode for the Assessment of Polyphenolics with Intermediate Antioxidant Power

open access: yesAntioxidants, 2022
A simple and rapid differential pulse voltammetric (DPV) method using a single-use electroactivated pencil graphite electrode (PGE*) is proposed for the rapid screening of the total content of polyphenolics (TCP) with intermediate antioxidant power (AOP)
Iulia Gabriela David   +8 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Tumour characteristics and survival in familial breast cancer prospectively diagnosed by annual mammography [PDF]

open access: yes, 2015
Women from breast cancer families without a demonstrable BRCA1/2 mutation were subjected to annual mammography from age 30 years onwards. One-hundred and ninety-eight patients were diagnosed prospectively with invasive breast cancer and followed for a ...
Evans, D. Gareth   +8 more
core   +1 more source

Immunoekspresja białka LAMP2 w ośrodkowym układzie nerwowym u osób chorych na sporadyczną postać choroby Creutzfeldta-Jakoba (sCJD)

open access: yesAktualności Neurologiczne, 2010
Wstęp: Sporadyczna postać choroby Creutzfeldta-Jakoba (sCJD) to śmiertelna choroba neurologiczna z grupy pasażowalnych encefalopatii gąbczastych (TSE). Ze względu na obecność polimorfizmu w kodonie 129.
Piotr Gębski, Beata Sikorska
doaj  

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

CUSTOMER ACCESS INFORMATION TECHNOLOGY (CAIT) DEPLOYMENT EVALUATION [PDF]

open access: yes, 1992
Customer access information technology offers great potential benefits to both the organization and its customers. However, managers lack methods for evaluating these technologies and determining whether conditions exist for success.
Kauffman, Robert J., Lally, Laura
core  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

The Thermodynamics of Quantum Systems and Generalizations of Zamolodchikov's C-theorem

open access: yes, 1993
In this paper we examine the behavior in temperature of the free energy on quantum systems in an arbitrary number of dimensions. We define from the free energy a function $C$ of the coupling constants and the temperature, which in the regimes where ...
A.H. Castro Neto   +21 more
core   +1 more source

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