Results 81 to 90 of about 1,623,979 (311)

Agrarumweltprogramm mit Ökobilanz im Allgäu zielorientiert gestalten [PDF]

, 2000
Mit einer Ökobilanz von 18 Grünlandbetrieben in den drei relevanten Förderprogrammen des Bayerischen Kulturlandschaftsprogramms „Intensiv” - quasi ohne Auflagen, „Extensiviert” - Verbot mineralischer Stickstoffdüngung - und „Ökologischer Landbau” wurden ...
Haas, Guido
core  

First records of the Indo-Pacific Finless Porpoise Neophocaena phocaenoides (G. Cuvier, 1829) (Cetartiodactyla: Phocoenidae) from Sri Lanka

Journal of Threatened Taxa, 2017
Thirty species of marine mammals have been recorded from Sri Lanka.  Amongst them the Indo-Pacific Finless Porpoise Neophocaena phocaenoides is the only representative of the family Phocoenidae.
Ranil P. Nanayakkara, Thomas A. Jefferson, Sandaruwan Abayaratne   +2 more
doaj   +1 more source

MicroRNAs of the miR-17~92 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression

eLife, 2020
Macrophages are critically involved in not only immune and inflammatory responses but also maintenance of metabolic fitness of organisms. Combined genetic deficiency of three clusters in the miR-17~92 family drastically shifted macrophage phenotypes ...
Xiang Zhang, Jianguo Liu, Li Wu, Xiaoyu Hu   +3 more
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Objectives and context of software measurement, analysis and control [PDF]

, 1992
Includes bibliographical references (p.

core  

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Investigating the impact of vaccine hesitancy on an emerging infectious disease: a mathematical and numerical analysis

Journal of Biological Dynamics
Throughout the last two centuries, vaccines have been helpful in mitigating numerous epidemic diseases. However, vaccine hesitancy has been identified as a substantial obstacle in healthcare management.
Indunil M. Hewage, Kevin E. M. Church, Elissa J. Schwartz   +2 more
doaj   +1 more source

A Utility-Based Rate Allocation of M2M Service in Heterogeneous Wireless Environments

International Journal of Distributed Sensor Networks, 2013
This paper presents a dynamic adaptive machine-to-machine (M2M) service rate allocation scheme for optimum traffic distribution in heterogeneous wireless environments (HWEs). According to the M2M service characteristics, it proposes the utility function,
Yao Huang, Hui Tian, Jie Zhang, Cheng Qin, Zhibo Wang   +4 more
doaj   +1 more source