Results 91 to 100 of about 65,238 (237)

D‐amino acid oxidase as a chemogenetic tool for spatiotemporally controlled hydrogen peroxide production: The oxygen connection

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose D‐amino acid oxidase (DAO) has been developed as a chemogenetic tool, to precisely manipulate redox levels in tissues and cells by generating H2O2 in the presence of D‐amino acids. The enzyme's significant oxygen consumption during H2O2 production may influence cellular oxygen levels.
Wiebke Maurer, Anke Zieseniss, Vamsi Priya Vikram, Yamin Chen, Laura Bauer, Annette Hillemann, Peter Rehling, Maithily S. Nanadikar, Diane de Zélicourt, Vartan Kurtcuoglu, Dörthe M. Katschinski   +10 more
wiley   +1 more source

The National Allergy Centre of Excellence–Addressing Australia's Allergy Burden

Clinical &Experimental Allergy, EarlyView.
Australia's high allergy burden prompted a national response, leading to the establishment of the National Allergy Centre of Excellence (NACE) in 2022. The NACE has advanced research infrastructure, collaboration, and consumer‐centred care through four pillars, achieving global recognition and accelerating translation into policy, practice, and ...
A. Young, J. J. Koplin, D. E. Campbell, J. M. Davies, H. Edmund, T. Jamieson, C. J. Hornung, T. O'Farrell, D. West, E. Kayes, L. A. Gray, R. L. Peters, L. Gamble, K. Gwynne, J. Lee, M. Lucas, C. H. Katelaris, M. D. O'Sullivan, D. J. Palmer, J. Trubiano, S. van Nunen, S. L. Vale, T. Wanandy, K. P. Perrett   +23 more
wiley   +1 more source

Evaluation of Dental Trauma Knowledge and ToothSOS Application Awareness Among Emergency Physicians

Dental Traumatology, EarlyView.
ABSTRACT Background/Aim Emergency physicians are among the first healthcare professionals to manage traumatic dental injuries, yet knowledge deficiencies may compromise early care. This study evaluated emergency physicians' knowledge of traumatic dental injury management, ToothSOS awareness, and factors independently associated with overall knowledge ...
Berkehan Aykanat, Hande Özyürek, Meryem Çoban Sezer, Bilal Ayaz, Ayşe Elif Bayar, Etkin Keskin, Taha Özyürek   +6 more
wiley   +1 more source

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

Journal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura, Ayana Tatsuno, Yamato Noto, Ryosuke Wakamatsu, Masayuki Sakunami, Ryu Kobayashi, Miki Yamashita   +6 more
wiley   +1 more source

Predictors of clinically significant bleeding in dogs with severe thrombocytopenia: 159 cases (2012‐2021)

Journal of Small Animal Practice, EarlyView.
Objectives To evaluate risk factors for clinically significant bleeding in dogs with severe thrombocytopenia and to assess whether predictors of bleeding differ between immune thrombocytopenia and other causes, and whether platelet mass is more predictive than platelet count.
G. Smith, E. D. Bennet, A. E. Ridyard
wiley   +1 more source

Urban ants as potential mechanical vectors of pathogenic and antibiotic‐resistant bacteria in a Brazilian hospital

Medical and Veterinary Entomology, EarlyView.
Nine ant taxa were identified in a Brazilian hospital, with Tapinoma melanocephalum and Dorymyrmex brunneus being the most abundant. Eighty‐five percent of collected ants yielded detectable bacterial growth, including clinically relevant genera such as Acinetobacter, Pseudomonas, Escherichia coli and Pluralibacter.
Luana Biggi Souza, Anny Karoliny de Lima Dionisio, Mayara Acioli Cedrim, Luiz Carlos Silva Dias Neto, Ellymaira Freitas Pontes, Yáskara Veruska Ribeiro Barros, Renato Júnior Cavalcante da Silva, Ênio Jose Bassi, Jacques Hubert Charles Delabie, Ana Lucia Biggi Souza, Leticia Anderson   +10 more
wiley   +1 more source

A Reassessment of Prophylactic Antibiotics in Low‐Infection‐Risk Electrophysiology Procedures

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Certain electrophysiology (EP) procedures are associated with minimal tissue disruption and do not involve permanent transvenous leads. As a result, these interventions carry a lower risk of device‐ or procedure‐related infection. These procedures include placement of implantable cardiac monitors, leadless pacemakers, and left atrial appendage
Rahel M. Sileshi, Katherine Mathes, Sathya Kosuri, Amulya Gupta, Neil Phillips, Rhea Pimentel, Martin Emert, Siva Soma, Rigoberto Ramirez, Raghuveer Dendi, Madhu Reddy, Seth H. Sheldon, Wissam El Atrouni, Larry M. Baddour, Amit Noheria   +14 more
wiley   +1 more source

The role of antibiotics in preventing surgical complications in periodontology and implant dentistry

Periodontology 2000, EarlyView.
Abstract Antibiotics are commonly prescribed in periodontal and implant surgeries, either before, during or after surgery, to prevent postoperative infection and reduce early implant failure. However, the potential benefits may be undermined by the risks of resistance and sensitization, thus requiring a strict indication for prescription.
Zhaozhao Chen, Lan‐Lin Chiou, Javier Calatrava, Hom‐Lay Wang   +3 more
wiley   +1 more source

Microbial oxidation of cephalosporins to cephalosporin sulfoxides.

Agricultural and Biological Chemistry, 1980
TORII, Hiroshi, ASANO, Tsuneo, MATSUMOTO, Norichika, KATO, Koichi, TSUSHIMA, Susumu, KAKINUMA, Atsushi   +5 more
openaire   +2 more sources

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source