Results 81 to 90 of about 102,957 (307)

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor   +12 more
wiley   +1 more source

Blood Stream Infection by Escherchia hermannii in a Neonate [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Escherichia hermannii is a Gram negative bacillus, facultative anaerobe and member of the family Enterobacteriaceae. It was earlier classified as Enteric Group 11 by the Enteric Section of Centers for Disease Control (CDC) and was reported in the ...
SMITA SOOD, SATYEN K HEMRAJANI
doaj   +1 more source

Epilepsy surgery: From bench to the clinics

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

THE STRATEGY OF ANTIMICROBIAL THERAPY OF ACUTE UNCOMPLICATED PYELONEPHRITIS FROM THE POSITION OF ETIOLOGICAL DATA

open access: yesИсследования и практика в медицине, 2015
:Acute pyelonephritis is one of the common diseases both in outpatient and in the hospital practice. The leading causative agent of this disease is E. coli.
A. D. Kaprin, A. A. Kostin, S. V. Popov
doaj   +1 more source

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc   +2 more
wiley   +1 more source

Characterization of Extended-Spectrum Beta-lactamase from Escherichia coli and Klebsiella Species from North Eastern Nigeria [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Resistance to antimicrobials has become a serious global health concern complicating treatment strategies and increasing health-care costs.
Yahaya Mohammed   +3 more
doaj   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

open access: yesFood Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei   +4 more
wiley   +1 more source

Total cervical occlusion: A solution after cervico‐isthmic cerclage failure

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Spontaneous preterm birth is mainly caused by cervical incompetence. Cervical cerclage is the gold standard for preventing mid‐trimester losses and preterm deliveries. If cervical cerclage fails, cervico‐isthmic cerclage may be indicated.
Déborah Couet   +5 more
wiley   +1 more source

Maternal infection in the context of actively managed prelabor rupture of membranes at term: An observational study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess maternal infection following prelabor rupture of membranes (PROM) at term in a setting where active management is recommended, and to identify associated risk factors. Methods A retrospective cohort study was conducted including pregnant women admitted to a Portuguese tertiary care center where immediate induction of labor ...
Inês Martins   +3 more
wiley   +1 more source

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