Results 101 to 110 of about 9,243,066 (309)

Maximizing insights from longitudinal epigenetic age data: simulations, applications, and practical guidance

Clinical Epigenetics
Background Epigenetic age (EA) is an age estimate, developed using DNA methylation (DNAm) states of selected CpG sites across the genome. Although EA and chronological age are highly correlated, EA may not increase uniformly with time.
Anna Großbach, Matthew J. Suderman, Anke Hüls, Alexandre A. Lussier, Andrew D. A. C. Smith, Esther Walton, Erin C. Dunn, Andrew J. Simpkin   +7 more
doaj   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

Advanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi, Xinmei Li, Yufan Hao, Qiaoyu Wu, Yuji Yu, Siyu Li, Nuo Xu, Yi‐Hsuan Wu, Eunhye Lee, Chi Chang, Emily Hu, Ying Lu, Elizabeth Delzell, Ann W. Hsing, Shankuan Zhu   +14 more
wiley   +1 more source

Demirjian’s and Cameriere’s Methods for the Assessment of Dental Age Estimation in Children from a Southern Brazilian City

Diagnostics
The chronological age estimation of living individuals is a crucial part of forensic practice and clinical practice, such as in orthodontic treatment.
Julia Carelli, Gabriela Sabrina da Silva, Mariana Vegini Gomes, Thais Vilalba, Flares Baratto-Filho, João Armando Brancher, Svenja Beisel-Memmert, Christian Kirschneck, Celia Maria Condeixa de França Lopes, Alexandre Moro, Erika Calvano Küchler   +10 more
doaj   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

A Real-time Service Oriented Infrastructure [PDF]

, 2010
The advancements in distributed computing have driven the emergence of service-based infrastructures that allow for on-demand provision of ICT assets. Taking into consideration the complexity of distributed environments, significant challenges exist in ...
Michael Boniface, Voith, T, Soren Berger, Cucinotta, T, Tommaso Cucinott, Dimosthenis Kyriazis, Voith, Thomas, Eduardo Oliveros, Oberle, K, Andreas Menychtas, Karsten Oberle, Kyriazis, D, Kyriazis, Dimosthenis, Menychtas, Andreas, Oliveros, Eduardo, Thomas Voith, Oberle, Karsten, Menychtas, A, Tommaso Cucinotta, Berger, Sören, George Kousiouris, Oliveros, E, Kousiouris, George, Berger, S, Boniface, Mike, Kousiouris, G, Cucinotta, Tommaso   +26 more
core   +1 more source

Bone Mineral Density in Children and Adolescents with Congenital Adrenal Hyperplasia

International Journal of Endocrinology, 2014
Chronic glucocorticoid therapy is associated with reduced bone mineral density. In paediatric patients with congenital adrenal hyperplasia, increased levels of androgens could not only counteract this effect, but could also advance bone age, with ...
Paulo Alonso Garcia Alves Junior, Daniel Luis Gilban Schueftan, Laura Maria Carvalho de Mendonça, Maria Lucia Fleiuss Farias, Izabel Calland Ricarte Beserra   +4 more
doaj   +1 more source

14C calendar chronologies and cultural sequences in 5th millennium BC in Slovenia and neighbouring regions

Documenta Praehistorica, 2012
In the paper, Bayesian analysis of 14C dates implemented in the OxCal program is used to develop calendric time-scale chronologies of individual sites and archaeological cultures of the 5th millennium calBC in Slovenia and Croatia.
Marko Sraka
doaj   +1 more source

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

Advanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo, Jinglei Wang, Xin Wang, Han Feng, Yize Zhao, Fadong Li, Shaobin Wei, Le Zhou, Zixu Zhao, Songjie Chen, Xiangyi Kong, Jue Wang, Liu He, Shijun Xia, Xin Li, Junmeng Zhang, Xiaoxia Liu, Xueyuan Guo, Ning Zhou, Songnan Li, Chenxi Jiang, Ribo Tang, Caihua Sang, Deyong Long, Xin Du, Jianzeng Dong, Wenwu Zhu, Changsheng Ma   +27 more
wiley   +1 more source

ROTEZ – THE ROMANIAN DATABASE OF ANCIENT HOARDS. MOMENTS OF VIOLENCE IN ROMAN TIMES

Journal of Ancient History and Archaeology, 2014
The article presents a new online application that is gathering,mapping and developing a database focused on the topic how the hoards’ hiding can represent moments of violence in ancient times.
Cristian Găzdac, Angela Lumezeanu
doaj   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source