Results 31 to 40 of about 995,911 (334)

Phospholipases A1 [PDF]

, 2011
Research in the author's laboratory is supported in part by a Wellcome Trust Senior Research Fellowship (067441), and Wellcome Trust project grants (086658 and 093228) and a Wellcome Trust Prize Studentship (G.S.R).Phospholipase A1 (PLA1) is an enzyme ...
Smith, Terry K., Gregory S. Richmond, Terry K. Smith, Richmond, Gregory S.   +3 more
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Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

Nature Medicine, 2018
Activation of microglia by classical inflammatory mediators can convert astrocytes into a neurotoxic A1 phenotype in a variety of neurological diseases1,2.
S. Yun, Tae-In Kam, Nikhil Panicker, Sangmin Kim, Y. Oh, Jong-sung Park, Seung-Hwan Kwon, Y. Park, Senthilkumar S. Karuppagounder, Hyejin Park, Sangjune Kim, Na-Hyun Oh, Nayoung Kim, Saebom Lee, Saurav Brahmachari, Xiaobo Mao, J. H. Lee, Manoj Kumar, Daniel An, Sung-Ung Kang, Yunjong Lee, Kang-Choon Lee, D. Na, Donghoon Kim, S. Lee, V. Roschke, S. A. Liddelow, Z. Mari, B. Barres, V. Dawson, Seulki Lee, T. Dawson, H. Ko   +32 more
semanticscholar   +1 more source

Minimally Invasive Facetectomy and Fusion for Resection of Extensive Dumbbell Tumors in the Lumbar Spine

Medicina, 2022
Background and Objectives: Resection of dumbbell tumors can be challenging, and facet joint sparing approaches carry the risk of incomplete resection. In contrast, additional facetectomy may allow better surgical exposure at the cost of spinal stability.
Michael Schwake, Emanuele Maragno, Marco Gallus, Stephanie Schipmann, Dorothee Spille, Bilal Al Barim, Walter Stummer, Michael Müther   +7 more
doaj   +1 more source

The schematic diagram of Anx-A1-enhanced HSV-1 attachment to cells.

, 2022
Anx-A1 binds HSV-1 gE, and Anx-A1 on virions enhances HSV-1 attachment in a versatile manner. Virion Anx-A1 either interacts with Anx-A1 on the cell surface or with FPR2.
Shun-Hua Chen (170609), Sheng-Min Hsu (12232893), Li-Chiu Wang (4681630), Pin Ling (11526262), Guey-Chuen Perng (3154932), Hui-Wen Yao (3078225), Shang-Rung Wu (719491), Yen-Chi Chiu (13215020)   +7 more
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Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β‐catenin modulator Annexin A1

EMBO Reports, 2019
Fusobacterium nucleatum, a Gram‐negative oral anaerobe, is a significant contributor to colorectal cancer. Using an in vitro cancer progression model, we discover that F.
M. R. Rubinstein, J. Baik, S. Lagana, R. Han, W. Raab, D. Sahoo, P. Dalerba, T. Wang, Yi-Ping W. Han   +8 more
semanticscholar   +1 more source

Normal aging induces A1-like astrocyte reactivity

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance In aging, the brain becomes vulnerable to injury and cognitive function declines, but the mechanisms responsible are unknown. Astrocytes, the most abundant class of glial cells, are vital for the proper function of the central nervous system,
Laura E. Clarke, S. A. Liddelow, C. Chakraborty, Alexandra E. Münch, M. Heiman, B. Barres   +5 more
semanticscholar   +1 more source

A1 astrocytes contribute to murine depression-like behavior and cognitive dysfunction, which can be alleviated by IL-10 or fluorocitrate treatment

Journal of Neuroinflammation, 2020
Background Astrocytes are crucial regulators in the central nervous system. Abnormal activation of astrocytes contributes to some behavior deficits. However, mechanisms underlying the effects remain unclear.
He-Yang Zhang, Yan Wang, Youdi He, Ting Wang, Xiao-Hui Huang, Chang-Ming Zhao, Lei Zhang, Si-Wei Li, Chang-Yong Wang, Yannv Qu, Xiao-Xia Jiang   +10 more
semanticscholar   +1 more source

Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis [PDF]

, 2011
Background The balancing functions of pro/anti-inflammatory mediators of the complex innate responses have been investigated in a variety of experimental inflammatory settings. Annexin-A1 (AnxA1) is one mediator of endogenous anti-inflammation, affording
Amílcar S Damazo, Damazo Amílcar S, Damazo, Amilcar S. [UNESP], Perretti, M, Perretti, Mauro, Oliani, Sonia M. [UNESP], Sampaio André LF, Sampaio, Andre L. F., Cintia MAG Nakata, Damazo, AS, Mauro Perretti, Nakata, Cintia M. A. G., Oliani, Sonia M., Roderick J Flower, Sonia M Oliani, Sampaio, ALF, Damazo, Amilcar S., Oliani, SM, Flower, Roderick J., Oliani Sonia M, Flower, RJ, André LF Sampaio, Flower Roderick J, Perretti Mauro, Nakata Cintia MAG, Nakata, CMAG   +25 more
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The Measurement of Human Capital Methods

Folia Oeconomica Stetinensia, 2016
Nowadays, knowledge and technology is a key factor supporting socio-economic development. Human capital gained crucial importance for the development, and became a major factor of the success.
Miciuła Ireneusz
doaj   +1 more source

A1-T175N shows a temperature-sensitive growth phenotype.

, 2022
(A) A1, A1-T175N or A1-D158N strains were serially diluted and spotted onto YPAD plates. The plates were incubated at 16°C for 5 days, 30°C, and 37°C for 2 days. (B and C) S. cerevisiae strains were grown at 30°C and 37°C respectively.
Sudipto Saha (64064), Thomas Nystrom (45125), Pradeep Kumar (310858), Jyoti Guleria (14094018), Deepak Sharma (131639), Navinder Kumar (814559), Abhirupa Ghosh (2807008), Nikhil Malik (14094024), Deepika Gaur (814560), Satinderdeep Kaur (14094021), Prashant Singh (729773)   +10 more
core   +1 more source