Results 81 to 90 of about 39,991 (302)

Changes in resting-state functional connectivity after stroke in a mouse brain lacking extracellular matrix components

Neurobiology of Disease, 2018
In the brain, focal ischemia results in a local region of cell death and disruption of both local and remote functional neuronal networks. Tissue reorganization following stroke can be limited by factors such as extracellular matrix (ECM) molecules that ...
Miriana Jlenia Quattromani, Jakob Hakon, Uwe Rauch, Adam Q. Bauer, Tadeusz Wieloch   +4 more
doaj   +1 more source

Peptide Thioester and Triazole Derivatives Through On‐Resin Dual‐Modification of Peptide Thiosulfonates

Angewandte Chemie International Edition, EarlyView.
An on‐resin dual‐modification strategy for peptides is presented, comprising S‐alkynylation of peptide thiosulfonates and regioselective iridium‐catalyzed azide–thioalkyne cycloaddition. This method reliably provides access to peptides with intricate non‐canonical modifications, being compatible with complex peptides, alkynes and azides.
Marius Werner, Agnes Bergmann, Chenxi Liu, Mira Behnam, Christian Klein, Franziska Thomas   +5 more
wiley   +1 more source

Tenant Participation In Social Housing Stock Management

Real Estate Management and Valuation, 2015
The aim of this paper is to present the concept, classification and significance of the involvement of tenants in the processes of managing council flats.
Suszyńska Katarzyna
doaj   +1 more source

Structural Biology and Protein Engineering of Thrombolytics

Computational and Structural Biotechnology Journal, 2019
Myocardial infarction and ischemic stroke are the most frequent causes of death or disability worldwide. Due to their ability to dissolve blood clots, the thrombolytics are frequently used for their treatment. Improving the effectiveness of thrombolytics
Jan Mican, Martin Toul, David Bednar, Jiri Damborsky   +3 more
doaj   +1 more source

Leading the Loop: Anchor‐Led Orchestration in Nascent Circular Ecosystems—A Qualitative Case Study

Business Strategy and the Environment, EarlyView.
ABSTRACT The transition towards a circular economy necessitates coordinated, systemic change across value chains. Yet the role of anchor firms in initiating and orchestrating nascent circular ecosystems remains underexplored. Using an inductive, qualitative single‐case design, we analyse a German mid‐sized entrepreneurial firm, drawing on 21 interviews
Johann Felix Mader, Patrick Spieth
wiley   +1 more source

Design of Social Infrastructure and Services Taking into Account Internal Migration by Age Cohort

Business Systems Research
European cities and regions are facing depopulation and an ageing population, leading to a shift in the demand and supply of goods and giving rise to the silver economy.
Drobne Samo, Bogataj Marija
doaj   +1 more source

Kliegl Bros. "pose slide" design artwork (Slides A13, A14, A15, and A16)

, 1890
Page [4] of original Kliegl Bros. "pose slide" design artwork on paper in binder, 1890s-early 1900s, undated. Page includes: A13 "Dressing", A14 "Dutch Girl", A15 "Evening Prayers", and A16 "Flowers! Flowers!"
Kliegl Bros. Universal Electric Stage Lighting Co.
core  

The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity

, 2004
LFM-A13, or alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide, was shown to inhibit Bruton's tyrosine kinase (Btk). Here we show that LFM-A13 efficiently inhibits erythropoietin (Epo)-induced phosphorylation of the erythropoietin ...
van den Akker, E (Emile), Löwenberg, Bob; id_orcid, van den Akker, Emile, Beug, H, van Dijk, Thamar, Schmidt, Uwe, von Lindern, Marieke, Beug, Hartmut, Schmidt, U, Löwenberg, Bob, Lindern, Marieke, van Dijk, Thamar B., Felida, Lamberto   +12 more
core   +1 more source

Net‐Zero Transition and Its Impact on Firms' Energy Efficiency and Economic Growth Within the Framework of Sustainable Development Goals: A Systematic Literature Review and Bibliometric Analysis

Business Strategy and the Environment, EarlyView.
ABSTRACT The transition to net zero (NZ) faces challenges such as uneven institutional readiness, fragmented policy frameworks and rising energy demands from population growth, economic expansion and artificial intelligence (AI). These obstacles are intensified by technological, financial and regulatory uncertainties that impede coordinated efforts ...
Mohamed Shrief, Jahira Debbarma, Lukman Akanbi, Duyen Chu   +3 more
wiley   +1 more source

Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse

, 2011
The A13 dopaminergic nucleus belongs to the incerto-hypothalamic area. It is thought to exert autonomous roles by integrating sensory input to autonomic, neuroendocrine, and motor output.
Clotman, Frédéric, Espana-Bessy, Agnès, Frédéric Clotman, Agnès Espana   +3 more
core   +1 more source