Results 21 to 30 of about 30,764 (208)

Potential mechanisms mediating PM2.5-induced alterations of H3N2 influenza virus infection and cytokine production in human bronchial epithelial cells

Ecotoxicology and Environmental Safety, 2023
Exposure to particulate matter (PM) has been associated with increased hospital admissions for influenza. Airway epithelial cells are a primary target for inhaled environmental insults including fine PM (PM2.5) and influenza viruses.
Yinbiao Wang, Rui Zhang, Fuyun Yang, Lin Yang, Qingmei Li, Junqing Guo, Xiao Liu, Jie Song, Guofu Zhang, Juan Li, Zhen An, Neil E. Alexis, Ilona Jaspers, Weidong Wu   +13 more
doaj   +1 more source

Natural co-infection of influenza A/H3N2 and A/H1N1pdm09 viruses resulting in a reassortant A/H3N2 virus

Journal of Clinical Virology, 2015
Despite annual co-circulation of different subtypes of seasonal influenza, co-infections between different viruses are rarely detected. These co-infections can result in the emergence of reassortant progeny.We document the detection of an influenza co-infection, between influenza A/H3N2 with A/H1N1pdm09 viruses, which occurred in a 3 year old male in ...
Rith, Sareth, Chin, Savuth, Sar, Borann, Y, Phalla, Horm, Srey Viseth, Ly, Sovann, Buchy, Philippe, Dussart, Philippe, Horwood, Paul F.   +8 more
openaire   +3 more sources

Explaining the geographical origins of seasonal influenza A (H3N2) [PDF]

Proceedings of the Royal Society B: Biological Sciences, 2016
Most antigenically novel and evolutionarily successful strains of seasonal influenza A (H3N2) originate in East, South and Southeast Asia. To understand this pattern, we simulated the ecological and evolutionary dynamics of influenza in a host metapopulation representing the temperate north, tropics and temperate south.
Frank Wen, Trevor Bedford, Sarah Cobey
openaire   +3 more sources

Surveillance in eastern India (2007-2009) revealed reassortment event involving ns and PB1-F2 gene segments among co-circulating influenza a subtypes

Virology Journal, 2012
Background Influenza A virus encodes for eleven proteins, of which HA, NA, NS1 and PB1-F2 have been implicated in viral pathogenicity and virulence.
Sarkar Mehuli, Chanda Shampa, Chakrabarti Sekhar, Mazumdar Jaydeep, Ganguly Anirban, Chadha Mandeep S, Mishra Akhilesh C, Chawla-Sarkar Mamta   +7 more
doaj   +1 more source

Outbreak of Influenza A (H3N2) Variant Virus Infection among Attendees of an Agricultural Fair, Pennsylvania, USA, 2011

Emerging Infectious Diseases, 2012
During August 2011, influenza A (H3N2) variant [A(H3N2)v] virus infection developed in a child who attended an agricultural fair in Pennsylvania, USA; the virus resulted from reassortment of a swine influenza virus with influenza A(H1N1)pdm09.
Karen K. Wong, Adena Greenbaum, Maria E. Moll, James Lando, Erin L. Moore, Rahul Ganatra, Matthew Biggerstaff, Eugene Lam, Erica E. Smith, Aaron D. Storms, Jeffrey R. Miller, Virginia Dato, Kumar Nalluswami, Atmaram Nambiar, Sharon A. Silvestri, James R. Lute, Stephen Ostroff, Kathy Hancock, Alicia Branch, Susan C. Trock, Alexander Klimov, Bo Shu, Lynnette Brammer, Scott Epperson, Lyn Finelli, Michael A. Jhung   +25 more
doaj   +1 more source

Amantadine-resistant influenza A (H3N2) viruses in Iran

Acta Virologica, 2009
Adamantanes have been used for the prophylaxis and treatment of Influenza A virus (IAV) infections worldwide. However, they have limited use because of increasing number of resistant viruses during recent years. In investigating the frequency of amantadine-resistant IAVs (H3N2) circulating in Iran in 2005-2008, we found that M2 sequences of recently ...
Yavarian, J., Azad, T., Jandaghi, N., Nategh, R.   +3 more
openaire   +2 more sources

Co-circulation and persistence of multiple A/H3N2 influenza variants in China

Emerging Microbes and Infections, 2019
The spread of influenza A/H3N2 variants possessing the hemagglutinin 121 K mutation and the unexpectedly high incidence of influenza in the 2017–2018 northern hemisphere influenza season have raised serious concerns about the next pandemic. We summarized
Weifeng Shi, Changwen Ke, Shisong Fang, Juan Li, Hao Song, Xiyan Li, Tao Hu, Jie Wu, Tao Chen, Lina Yi, Yingchao Song, Xin Wang, Weijia Xing, Weijuan Huang, Hong Xiao, Lijun Liang, Bo Peng, Weihua Wu, Hui Liu, William J. Liu, Edward C. Holmes, George F. Gao, Dayan Wang   +22 more
doaj   +1 more source

Whole-genome sequences of two influenza A (H3N2) virus strains isolated from Qinghai, China

Biosafety and Health, 2021
Influenza A (H3N2) virus has a faster evolution rate than other types of influenza viruses. In this study, whole genome sequencing was performed to better understand the molecular evolution of influenza H3N2 and the protective effect of influenza virus ...
Juan Yu, Shengcang Zhao, Huaxiang Rao
doaj   +1 more source

Triple Reassortant H3N2 Influenza A Viruses, Canada, 2005

Emerging Infectious Diseases, 2006
Since January 2005, H3N2 influenza viruses have been isolated from pigs and turkeys throughout Canada and from a swine farmer and pigs on the same farm in Ontario. These are human/classical swine/avian reassortants similar to viruses that emerged in US pigs in 1998 but with a distinct human-lineage neuraminidase gene.
Christopher W. Olsen, Alexander I. Karasin, Suzanne Carman, Yan Li, Nathalie Bastien, Davor Ojkic, David Alves, George Charbonneau, Beth M. Henning, Donald E. Low, Laura Burton, George Broukhanski   +11 more
openaire   +3 more sources

An epitope-optimized human H3N2 influenza vaccine induces broadly protective immunity in mice and ferrets

npj Vaccines, 2022
There is a crucial need for an improved H3N2 influenza virus vaccine due to low vaccine efficacy rates and increased morbidity and mortality associated with H3N2-dominated influenza seasons.
Brianna L. Bullard, Jennifer DeBeauchamp, Matthew J. Pekarek, Erika Petro-Turnquist, Peter Vogel, Richard J. Webby, Eric A. Weaver   +6 more
doaj   +1 more source